4 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Small-molecule Inhibitor Leads Versus emerging and neglected RNA viruses (SILVER)
Date du début: 1 oct. 2010, Date de fin: 31 mars 2015,
RNA virus infections kill millions of humans annually, largely due to the lack of suitable vaccines and drugs to control them. This problem is addressed in this FP7 call and in response a consortium of Europe’s and Asia’s leading molecular virologists, structural biologists, medicinal chemists and bioinformaticians has been brought together to generate a state-of-the-art drug discovery and design ...
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25
Participants partenaires
TERMINÉ
European Training Network on (+)RNA Virus Replication and Antiviral Drug Development (EUVIRNA)
Date du début: 1 mars 2011, Date de fin: 28 févr. 2015,
Virus infections remain a major cause of disease, with dramatic costs in mortality, morbidity, and economic loss worldwide. There is an unmet need for potent antiviral drugs, in particular against viruses with a (+)RNA genome which include many important pathogens of humans and animals.Antiviral drug development requires a detailed understanding of virus replication and effective translation of th ...
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12
Participants partenaires
TERMINÉ
Development of novel antiviral drugs against Influenza (FLUCURE)
Date du début: 1 oct. 2010, Date de fin: 30 sept. 2014,
"Influenza viruses cause a highly contagious respiratory disease in both humans and animals. Typically, influenza spreads worldwide in seasonal epidemics resulting in an estimated 3 to 5 million cases of severe illness and 250,000 to 500,000 deaths annually. In addition to these seasonal epidemics there have been several pandemics since the early 1900’s, where highly virulent strains emerged, the ...
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11
Participants partenaires
TERMINÉ
Small Molecule Inhibitors of the Trimeric Influenza Virus Polymerase Complex (FLUINHIBIT)
Date du début: 1 avr. 2008, Date de fin: 31 mars 2010,
"The clock is counting down to the next influenza pandemic. Since 1997, the avian influenza virus strain H5N1 has infected over 250 people worldwide with a fatality rate of ~60%, although so far without sustained human-to-human transmission. In view of the very few efficacious drugs against influenza virus infections and the time it takes to develop a matching vaccine, there is an unmet worldwide ...
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