6 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Resetting the THYRoid axis for prevention of AGE-related diseases and co-morbidities (THYRAGE)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,
We hypothesize that inappropriate thyroid hormone action in target cells is a common mechanism underlying susceptibility to age-related degenerative diseases and co-morbidities. Although regulation of systemic thyroid status is well understood and underpins treatment of common thyroid disease, it is only in the last decade that the importance of local regulation of thyroid hormone action in tissue ...
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7
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TERMINÉ
Engineering responsive and biomimetic hydrogels for biomedical therapeutic and diagnostic applications (BIOGEL)
Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,
BIOGEL is set up to educate young scientists to develop innovative hydrogel chemistries and systems for biomedical applications. The first objective is to provide a platform for young researchers to undergo a well-rounded PhD education, particularly focussed on translational skills for a career focused in biomedical research and medical technology development. The second objective is to engineer f ...
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9
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TERMINÉ
WNT-mediated signal relay in stem cells and oncogenesis - from basic biology to applications (WntsApp)
Date du début: 1 août 2013, Date de fin: 31 juil. 2017,
The ITN WntsApp is organized to achieve 3 key aims: (i) Provide a committed training programme for young researchers to bridge the gap between basic scientific knowledge and drug development, (ii) Centring research on a key cancer-signalling pathway, WNT signalling, to stimulate synergies and (iii) Strengthening the link between international partners and private enterprises to stimulate innovatio ...
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10
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TERMINÉ
Biofunctionalized Metal and Magnetic Nanoparticles for Targeted Tumor Therapy (NANO3T)
Date du début: 1 août 2008, Date de fin: 31 juil. 2011,
The cause of diseases is often unknown, but their origin can frequently be found at the biomolecular and cellular level situated on nm-scale. Early diagnostics combined with early intervention on that nanoscale is one of the holy grail of modern medicine. Inorganic nanoparticles are very promising agents in that respect. One of the promising biomedical applications of these nanoparticles is their ...
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8
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TERMINÉ
Targeting LRP5 to Increase Bone Formation in Osteoporosis (TALOS)
Date du début: 1 mai 2008, Date de fin: 30 avr. 2011,
"The balance between bone resorption and bone formation determines the mass and structural integrity of the skeleton and is disturbed in osteoporosis. In contrast to the molecular mechanisms regulating bone resorption, knowledge of the mechanisms regulating bone formation is limited. A recent breakthrough has been the identification of a link between bone mass in humans with rare bone disorders an ...
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9
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TERMINÉ
On-chip simultaneous intracellular recording and stimulation of electrical and biochemical activities from hundreds of neurons (BRAIN STORM)
Date du début: 1 janv. 2008, Date de fin: 31 déc. 2010,
In the BRAINSTORM project, we aim to develop an integrated system enabling on-chip intracellular recordings from a relatively large cultured neuronal network combined with chemical sensing and intracellular delivery of biologically active molecules. To achieve tight coupling with the cell membrane and enable efficient recordings, micronail-type probes will be integrated with a CMOS readout circuit ...
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