11 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Advanced Immunization Technologies (ADITEC)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2017,
Vaccines so far have been developed mostly by following an empiric approach. To prevent and possibly cure unresolved and emerging infectious diseases we need to fully exploit the potential of the human immune system. Progress in science and technology makes it possible to achieve what was previously deemed impossible. The scope of this project is to produce knowledge necessary to develop novel and ...
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53
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TERMINÉ
Nuclear Dynamic, Organization and Genome Stability (NDOGS)
Date du début: 1 févr. 2012, Date de fin: 31 janv. 2017,
The eukaryotic genome is packaged into large-scale chromatin structures occupying distinct domains in the cell nucleus. Nuclear compartmentalization has recently been proposed to play an important role in genome stability but the molecular steps regulated remain to be defined. Focusing on Double strand breaks (DSBs) in response to which cells activate checkpoint and DNA repair pathways, we propose ...
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1
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TERMINÉ
Biomarkers For Enhanced Vaccine Safety (BIOVACSAFE)
Date du début: 1 mars 2012, Date de fin: 31 déc. 2016,
BioVacSafe is a concise consortium of selected academic, public, and SME participants used to co-working in industry-led projects, organised into focused Activity Cores to generate knowledge and tools to benchmark licensed vaccine reactogenicity, and create practical and generalizable guidelines and techniques to enhance immunosafety of novel vaccines from pre-development to post-marketing surveil ...
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24
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TERMINÉ
Microbicide Optimization Through Innovative Formulation for Vaginal and Rectal Delivery (MOTIF)
Date du début: 1 oct. 2012, Date de fin: 31 mars 2016,
"The 40% protection against HIV-1 infection with vaginally-applied tenofovir gel demonstrated in the CAPRISA004 trial, has emphasized development of anti-retroviral (ARV)-based microbicides. Combining ARVs in a single product may provide increased protection. Development of a generally applicable formulation platform for combining ARVs (even if chemically incompatible) and understanding of the pro ...
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9
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TERMINÉ
Realizing the European Network in Biodosimetry (RENEB)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,
Creating a sustainable network in biological dosimetry that involves a large number of experienced laboratories throughout the EU will significantly improve the accident and emergency response capabilities in case of a large-scale radiological emergency. A well organised cooperated action involving EU laboratories will offer the only chance for a fast and trustworthy dose assessment urgently neede ...
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28
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TERMINÉ
Hydroxitirosol, a new generation of microbicides targeting HIV through antiviral and anti-inflammatory pathways (AIM-HIV)
Date du début: 1 déc. 2012, Date de fin: 31 mai 2015,
Since the first cases of AIDS were reported 30 years ago, HIV remains a difficult target for the research field. Although there is no cure for AIDS, HIV infection can be prevented, however in many countries across the world access to prevention and treatment services is limited. Global leaders have pledged to work towards universal access to HIV prevention and care, so that millions of deaths can ...
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4
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TERMINÉ
European Consortium for Stem Cell Therapy for Neurodegenerative Diseases (NEuroStemCell)
Date du début: 1 déc. 2008, Date de fin: 31 mai 2013,
The NEuroStemCell consortium will foster collaboration between leading European experimental and clinical researchers in order to maximise the prospects for successful clinical trials of stem cell therapy for Parkinson's (PD) and Huntington's (HD) Disease. The activities will be driven by a Clinical WorkPackage (WP), which will set the requirements, and monitor and guide advances in development of ...
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15
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TERMINÉ
Hybrid Fluorescence Molecular Tomography and X-ray Computed Tomography system and method (FMTXCT)
Date du début: 1 mars 2008, Date de fin: 31 août 2012,
"This proposal offers to combine X-ray CT (XCT) and Fluorescence Molecular Tomography (FMT) into a hybrid, quantitative system and method. The project builds on state-of the-art knowledge that only recently became available in different European states as represented by the partners herein. In return it delivers the first such hybrid system worldwide. The system will operate by 1) co-registering ...
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8
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TERMINÉ
Role of astrocytes in Huntington's Disease: characterization of a novel mouse model with targeted expression of mutant huntingtin in the striatum (ASTRO-HD)
Date du début: 2 août 2010, Date de fin: 1 août 2012,
"Huntington’s disease (HD) is an inherited neurodegenerative disease, which has no cure, resulting from the mutation of the gene coding for huntingtin protein (htt). Clinically, HD patients present with progressive involuntary spasmodic movements and cognitive impairments. Post-mortem studies of HD patients reveal severe atrophy of the striatum, reflecting a selective neuronal loss of medium spiny ...
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1
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TERMINÉ
Advanced gene therapy tools for treatment of CNS-specific disorders (NEUGENE)
Date du début: 1 oct. 2008, Date de fin: 31 mars 2012,
"Curative therapies still do not exist for most CNS diseases but gene therapy is a promising new approach. We propose that it will be possible to modify brain function and pathophysiology by targeted delivery of specific curative factors to selected populations of brain cells that are affected by disease. This opens the door for effective treatment regimes, which can be tailored to individual pati ...
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6
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TERMINÉ
The European Advanced Translational Research Infrastructure in Medicine (EATRIS)
Date du début: 1 janv. 2008, Date de fin: 31 déc. 2010,
Efficient translation of research discoveries into industrial application is an essential element to maintain Europe’s competitiveness in the biomedical and health industry. The main bottleneck is the lack and the fragmented nature of essential research infrastructure and know-how, leading to unacceptable delays and/or preventing the development of new innovative medicines. The aim of EATRIS is to ...
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