5 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
European Gram Negative Antibacterial Engine (ENABLE)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2020,
The intensive use and misuse of antibiotics has resulted in some level of antibiotic resistance in essentially all human bacterial pathogens. There is a growing concern that the loss of therapeutic options will present us with a post-antibiotic era where present and future medical advances are negated. Resistant bacteria dramatically reduce the possibilities of treating infections effectively, a ...
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42
Participants partenaires
TERMINÉ
Nanotherapeutics for antibiotic resistant emerging bacterial pathogens (NAREB)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,
Increase in antibiotic resistance is a global concern worldwide. The project NAREB's main objective is the optimization of several nanoformulations of antibacterial therapeutics in order to improve the therapy of multi-drug resistant (MDR) tuberculosis (TB) and MRSA infections in European MDR patients.NAREB will address the problem of drug bioavailability inside the infected macrophages, transport ...
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16
Participants partenaires
TERMINÉ
Functional organisation of penicillin binding proteins of Neisseria meningitidis (NMEN-PBP)
Date du début: 1 nov. 2009, Date de fin: 31 oct. 2012,
"Neisseria meningitidis (Nm) is a leading cause of bacterial meningitis and septicemia worldwide with a high case-fatality rate. Although penicillin remains the drug of choice in the treatment of IMD, an increasing number of meningococci with reduced susceptibility to penicillin have been emerging worldwide. Reduces susceptibility or resistance to penicillin in meningococci is connected to alterat ...
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1
Participant partenaire
TERMINÉ
CONtrol of COmmunity-acquired MRSA: Rationale and Development of counteractions (CONCORD)
Date du début: 1 janv. 2009, Date de fin: 30 juin 2012,
"Until recently, methicillin-resistant Staphylococcus aureus (MRSA) were confined to hospitals (HA-MRSA). However, community- and farm-associated MRSA (CA-and FA-MRSA) has developed as an important cause of infections. No strategies exist to combat these MRSA. CONCORD is aimed at explaining the ecological success in the community and the farm environment of CA- and FA-MRSA in contrast to HA-MRSA i ...
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9
Participants partenaires
TERMINÉ
Combating Antibiotics Resistant Pneumococci by Novel Strategies Based on in vivo and in vitro Host – Pathogen Interactions (CAREPNEUMO)
Date du début: 1 mars 2009, Date de fin: 29 févr. 2012,
...ogen interactions and identification of potential therapeutic targets and vaccine candidates, 3. providing a basis for the development of improved vaccine and intervention strategies. This joint international effort would contribute towards novel control strategies, especially of antibiotic resistant S. pneumoniae strains."
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