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Pemphigus is a potentially lethal bullous disease of the skin and mucosa and may be considered as a paradigmatic organ-specific autoimmune disease due to 1) its well-defined autoantigens, 2) the knowledge of critical events of its immune pathogenesis and 3) the reproducibility of major clinical and pathogenic features in suitable animal models. Overall, understanding the etiopathogenesis of pemphi ...

Several industries have an increasing interest in improving their access to pure single enantiomers of biologically active substances. The latter often form the basis for valued added products relevant for, among others, the pharmaceutical, cosmetic, and food industries. Up to now there exist two generally rivalling concepts for producing pure enantiomers. One approach is based on developing and a ...