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Extracellular brain proteolysis in neuronal plasticity and neuropsychiatric disorders (EXTRABRAIN)
Date du début: 1 sept. 2013, Date de fin: 31 août 2017,
Brain disorders comprise a major burden for the society. Recent analyses of the neuropsychiatric disease-related gene polymorphisms as well as genomics and proteomics have identified the components of the extracellular matrix (ECM) and the cell adhesion molecules (CAMs) in the brain as pivotal for those diseases. The ECM/CAMs span the synaptic cleft and regulate the synaptic dynamics. Furthermore, ...
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