2 projets européens trouvés
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TERMINÉ
Multiple manifestations of genetic and non-genetic factors in Multiple Sclerosis disentangled with a multi-omics approach to accelerate personalised medicine (MultipleMS)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,
The complex interactions between genetic and non-genetic factors produce heterogeneities in patients as reflected in the diversity of pathophysiology, clinical manifestations, response to therapies, disease development and progression. Yet, the full potential of personalized medicine entails biomarker-guided delivery of efficient therapies in stratified patient populations.MultipleMS will therefor ...
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TERMINÉ
NOX enzymes as mediators of inflammation-triggered neurodegeneration: modulating NOX enzymes as novel therapies (NEURINOX)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2016,
NEURINOX aims at elucidating the role of NADPH oxidases (NOX) in neuroinflammation and its progression to neurodegenerative diseases (ND), as well as evaluating the potential of novel ND therapeutics approaches targeting NOX activity. NOX generate reactive oxygen species (ROS) and have emerged as regulators of neuroinflammation. Their role is complex: ROS generated by NOX lead to tissue damage in ...
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