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8 projets européens trouvés

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 TERMINÉ 
The worldwide spread of antibiotic-resistant microorganisms can be viewed as an ecological consequence of the systematic use of antimicrobial agents. Resistant bacteria prevail in healthcare environments where antibiotic selective pressure is intensive. Novel therapeutic approaches are urgently required to deliver the well-documented existing drugs in an optimized fashion to: i) protect them towar ...
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 11

 TERMINÉ 
The present project is aimed to the development of a multi-step process for the production of second-generation biofuels from lignocellulosic biomass in a cost-efficient way through the use of tailored nanostructured catalysts. The proposed process is based on the cascade combination of three catalytic transformations: catalytic pyrolysis, intermediate deoxygenation and hydrodeoxygenation. The seq ...
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 18

 TERMINÉ 
The main objective of this research proposal is to identify and elaborate those characteristics of ENM that determine their biological hazard potential. This potential includes the ability of ENM to induce damage at the cellular, tissue, or organism levels by interacting with cellular structures leading to impairment of key cellular functions. These adverse effects may be mediated by ENM-induced a ...
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 40

 TERMINÉ 

Vascular Endothelial interactionS and SpEciaLization (Vessel)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

The vascular network plays essential roles in animal biology. Local disruption or impaired function of the vascular network is known to cause various pathological conditions, such as ischemic heart disease and stroke. The angiogenic growth of blood vessels is critically required during development, growth and regeneration, but it can also promote the growth of cancer cells and contribute to diabet ...
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 9

 TERMINÉ 
The growing development, production and use of engineered nanomaterials and associated products will increase exposure of both humans and ecosystems to these new materials. However, current knowledge is still incomplete and established test methods are as yet inappropriate to reliably assess the extent of exposure and risk of materials at the nano-scale. There is an urgent need to develop methods ...
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 32

 TERMINÉ 

Open Collaborative Model for Tuberculosis Lead Optimisation (ORCHID)

Date du début: 1 janv. 2011, Date de fin: 30 juin 2015,

"Early stage Drug Discovery efforts over the last 5 years have resulted in the identification of a number of promising lead compounds in the fight against TB. These leads need to be further progressed and optimised into candidates for pre-clinical development through the Drug Development progression cascade.Three compound families are of particular interest: 1) InhA Inhibitors, 2) New potent whole ...
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 14

 TERMINÉ 
Objective of the NanoSustain project is to develop innovative solutions for the sustainable design, use, recycling and final treatment of nanotechnology-based products This will be achieved by a comprehensive data gathering and generation of relevant missing data, as well as their evaluation and validation, for specific nanoproducts or product groups in relation to their human health and environme ...
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 12

 TERMINÉ 
Dendrimers are new materials obtained with a highly controlled molecular structure in several space orientations. Liquid Crystals (LC) Dendrimers are a part of them that incorporate directional properties to these materials. If we append active molecules into these engineered molecules, we can obtain multifunctional anisotropic molecules that open the possibility of achieving a wide variety of phy ...
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 10