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20 projets européens trouvés

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 TERMINÉ 

TRansforming Institutions by Gendering contents and Gaining Equality in Research (TRIGGER)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2017,

TRIGGER aims at promoting systemic interventions designed to have deep, long lasting and widespread impacts at all the different levels in 5 research organisations. The project, coordinated and co-funded by the Italian Government, assisted by an institute specialised in gender and science, involves as co-funders five universities from different EU countries (Czech Republic, France, Italy, UK, Spai ...
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 11

 TERMINÉ 

European Medical Information Framework (EMIF)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,

In response to the need to tackle increasingly complex medical research questions, a growing amount of human health data is being collected, either in routine Electronic Healthcare Record (EHR) databases, through research-driven cohort studies, in biobanks or related efforts. However, data sources are typically fragmented and contain information gaps which prevent their full exploitation. EMIF aim ...
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 64

 TERMINÉ 

Drug Disease Model Resources (DDMORE)

Date du début: 1 mars 2011, Date de fin: 31 août 2016,

Model based-drug development (MBDD) is accepted as a vital approach in understanding patient risk/benefit and attrition. At the core of MBDD lies Modelling and Simulation (M&S), a technology providing the basis for informed, quantitative decision-making.M&S facilitates the continuous integration of available information related to a drug or disease into constantly-evolving mathematical models capa ...
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 28

 TERMINÉ 

Improving beta-cell function and identification of diagnostic biomarkers for treatment monitoring in diabetes (IMIDIA)

Date du début: 1 févr. 2010, Date de fin: 30 sept. 2015,

An absolute or relative loss of beta-cell mass and function underlie the development of type I and type 2 diabetes.Preventing beta-cell demise or restoring their number and function is a major therapeutic goal. However,development of novel diagnostic and prognostic tools, and of novel therapeutic modalities, is hampered by the limited knowledge of the molecular pathways that control beta-cell demi ...
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 23

 TERMINÉ 

Investigating the Roles and Mechanisms of Action of Estrogens via Estrogen Receptor ß in Granulosa Cell Tumours of the Ovary (ESTROVARYTUMOUR)

Date du début: 1 mars 2011, Date de fin: 21 juin 2015,

"Granulosa cell tumours (GCT) are a rare form of malignancy affecting women of all ages. Because GCT display a high propensity to recurrence and there is no efficient curative treatment beyond surgery, ~ 20% of adult patients die of the consequences of their tumour. However, despite the importance and insidiousness of GCT, very little is known of its molecular etiology. Although most GCT produce e ...
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 1

 TERMINÉ 

Advanced optoelectronic Devices with Enhanced QUAntum efficiency at THz frEquencies (ADEQUATE)

Date du début: 1 mai 2010, Date de fin: 30 avr. 2015,

The aim of this project is the realisation of efficient mid-infrared and THz optoelectronic emitters. This work is motivated by the fact that the spontaneous emission in this frequency range is characterized by an extremely long lifetime when compared to non-radiative processes, giving rise to devices with very low quantum efficiency. To this end we want to develop hybrid light-matter systems, alr ...
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 1

 TERMINÉ 

TreatPolyQ – Industrial Academic Initial Training Network towards treatment of Polyglutamine Diseases (TREATPOLYQ)

Date du début: 1 mars 2011, Date de fin: 28 févr. 2015,

Protein aggregation is a hallmark of many late onset neurodegenerative disorders including Parkinson’s Disease (PD), Alzheimer’s Disease (AD), amyotrophic lateral sclerosis (ALS), prion diseases as well as the group of polyglutamine diseases (polyQ). The aim of this proposal is to create a network of European partners bridging important basic mechanisms involved in proteinopathies, research of mod ...
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 17

 TERMINÉ 

Graphene-based Electrodes for Application in Supercapacitors (ElectroGraph)

Date du début: 1 juin 2011, Date de fin: 31 mai 2014,

For vehicle applications, it is desirable to have devices with high energy density, high power density, long cycle and shelf life, and low cost. Supercapacitors are considered one of the newest innovations in the field of electrical energy storage. In hybrid electric vehicle, supercapacitors can be coupled with fuel cells or batteries to deliver the high power needed during acceleration as well as ...
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 10

 TERMINÉ 

Staff Exchanges to estimate vegetation structure and biochemistry from remote sensing in connection to carbon and water fluxes (SENSORVEG)

Date du début: 1 mai 2010, Date de fin: 30 avr. 2014,

Remote sensing can provide systematic global estimations of vegetation structure and biochemistry imparting data such as leaf area index (LAI), water content or fractional light interception by green vegetation (fPAR). However a global network of standardize validation sites is required to reduce the uncertainty of these products. As part of that effort, SpecNet (Spectral Network), an independent ...
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 5

 TERMINÉ 

From Mathematical Logic To Applications (MALOA)

Date du début: 1 oct. 2009, Date de fin: 30 sept. 2013,

"Mathematical logic is a rapidly-developing subject with sophisticated techniques and many applications in algebra, geometry, number theory, analysis, and computer science. Even though the branches of logic share vital concepts and techniques, in recent years increased specialism has meant that most researchers are trained in just one branch of logic, and there is a need in Europe for researchers ...
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 8

 TERMINÉ 

Therapeutic challenge in Leukodystrophies: Translational and ethical research towards clinical trials (LEUKOTREAT)

Date du début: 1 mars 2010, Date de fin: 31 août 2013,

Leukodystrophies (LDs) are inherited rare neurodegenerative diseases of the white matter and its main component, the myelin, that are affecting predominantly children. Severity of the disease is related to the axonal dysfunction due to myelin deficiency or destruction. Despite the achievement of remarkable advances made in the past decade, there is no current curative therapy. The development of t ...
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 25

 TERMINÉ 

RISK ASSESSMENT OF ENGINEERED NANOPARTICLES (ENPRA)

Date du début: 1 mai 2009, Date de fin: 31 oct. 2012,

Engineered Nanoparticles (ENP) are increasingly produced for use in a wide range of industrial and consumer products. Yet it is known that exposure to some types of particles can cause severe health effects. Therefore it is essential to ascertain whether exposure to ENP can lead to possible health risks for workers and consumers. We have formed a consortium of well-known scientists from European U ...
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 18

 TERMINÉ 

Development of methodology for alternative testing strategies for the assessment of the toxicological profile of nanoparticles used in medical diagnostics (NanoTEST)

Date du début: 1 avr. 2008, Date de fin: 31 mars 2012,

Nanoparticles (NP) have unique, potentially beneficial properties, but their possible impact on human health has not been adequately assessed. The main goal of this proposal is to develop alternative high-throughput testing strategies using in vitro and in silico methods to assess the toxicological profile of NP used in medical diagnostics. Our specific aims are to: 1. Define NP properties and ful ...
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 12

 TERMINÉ 

Structural Analysis of Mathematical Proofs (STRUCTPROOFS)

Date du début: 1 nov. 2009, Date de fin: 31 oct. 2011,

"Proof Theory is the branch of mathematical logic that investigates formal proof systems modelling mathematical reasoning. There are different types of proof systems, each having its own advantages and disadvantages. A certain class of proof systems (Gentzen-type systems) has the interesting property of exhibiting a geometric structure in proofs. Logical and proof-theoretic problems that are formu ...
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 1

 TERMINÉ 

Study of magnetic responsive biopolymer based materials (MAGBIOMAT)

Date du début: 1 oct. 2009, Date de fin: 30 sept. 2011,

"The aim of the proposed project is to synthesize and characterize new nanostructured magneto-responsive biopolymer-based materials by the introduction of functionalized magnetic nanoparticles in biogel and foam to gain a deeper understanding of two fundamental aspects: - The understanding of the formation mechanisms of such structures: magneto-responsive networks. - The correlation between the be ...
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 1

 TERMINÉ 

High-energy cosmic neutrinos astronomy using a Mediterranean undersea telescope (NEUTEL-APC)

Date du début: 1 juin 2008, Date de fin: 31 mai 2011,

"The observation of high-energy cosmic neutrinos, produced in distant astrophysical accelerators (and possibly by means of more exotic processes as well), has turned into one of the major challenges of today’s astroparticle physics, motivated by the possibility to open a new observational window on the distant Universe. The present project is a contribution to the experimental effort being carried ...
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 1

 TERMINÉ 

Synthesis of innovative organic semiconductors based on functionalized tetracenes and derivatives of rubrene (TETRA-FUN)

Date du début: 1 juin 2009, Date de fin: 31 mai 2011,

"Organic semiconductors represent a real alternative to inorganic semiconductors for many applications, since they present some evident advantages: are lighter, cheaper, compatible with large area, flexible devices. One of the most promising molecular organic semiconductor is rubrene (5,6,11,12-tetra-phenyl-tetracene); single crystals of rubrene showed hole mobility comparable with that of amorpho ...
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 1

 TERMINÉ 

NoE PolyNET - Network of Excellence for the exploitation of organic and large area electronics (PolyNet)

Date du début: 1 janv. 2008, Date de fin: 31 déc. 2010,

Description Network of Excellence for the exploitation of organic and large-area electronicsThe Network of Excellence (NoE) PolyNet aims to establish Europe in the area of organic and large area electronics as the world leader in science, technology development and subsequent commercial exploitation of printing and large area technologies ...
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 18

 TERMINÉ 

ANALYSIS OF PML/RARA ONCOGENIC COMPLEX IN ACUTE PROMYELOCYTIC LEUKEMIA (APL)

Date de fin: 1 nov. 2010,

"Acute promyelocytic leukemia (APL) appears to be primarily a monogenic disease characterised by a specific t(15 ;17) translocation that fuses the PML and the RARA gene to generate a PML/RAR fusion protein. PML/RARA is a transcriptional repressor, and RARA homo-dimerisation through the coiled coil of PML was believed to be the basis for repression via enhanced binding of co-repressors. Clinically ...
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 2

 TERMINÉ 

The epistemology of biopolitics (Biopolitics)

Date du début: 1 oct. 2008, Date de fin: 31 mars 2010,

The epistemology of biopolitics: rediscovering Georges Canguilhem This research project will cast new light on the works of the philosopher of life and medical sciences, Georges Canguilhem. In the second half of the Twentieth Century a new and pressing issue emerged in international intellectual discourse: the ability of scientific rationality to intervene in the evolution of the human species. I ...
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 1