3 projets européens trouvés
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TERMINÉ
Elucidating the role of the entorhinal cortex through precise optogenetic and pharmacogenetic manipulations (ENTORHINAL SILENCING)
Date du début: 1 mars 2012, Date de fin: 28 févr. 2014,
The hippocampal-entorhinal circuit is critical for the formation of new episodic memories, or memories of events that happen in a specific place and time. The discovery of cells in this circuit that respond to the animal's location in the environment suggests that these cells create a spatial context for such memories. Within this broad neural circuit, five key cell types have been described: plac ...
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1
Participant partenaire
TERMINÉ
Space coding in hippocampo-entorhinal neuronal assemblies (SPACEBRAIN)
Date du début: 1 févr. 2008, Date de fin: 31 juil. 2011,
"Despite impressive advances in almost every field of neuroscience, our insights into brain function remain largely confined to its building blocks at the microscopic level, and to phenomenological descriptions at the macroscopic level. Understanding how complex mental functions originate from electrical and chemical processes in brain cells requires a comprehensive and integrated multi-level anal ...
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7
Participants partenaires
TERMINÉ
Spatial representation in the entorhinal neural circuit (Entorhinal Circuits)
Date du début: 1 mars 2009, Date de fin: 28 févr. 2011,
Behavioral unit recordings of rats exploring an open field have shown that medial entorhinal cortex (mEC) neurons have spatially specific firing fields that repeat at regular intervals. Called ‘grid cells’, the field size and spacing of firing activity changes along the dorsal-ventral axis of mEC. In vitro recordings of the same cell population has shown dorsal-ventral changes in the intrinsic pro ...
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