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 TERMINÉ 
Although vaccination is the cornerstone of prophylaxis, current vaccines provide only moderate protection. Most employ inactivated or protein-based, including multimeric antigen, vaccines requiring annual updating. Their limited antigen loads provide limited capacity for inducing robust immune defences, without assurance that both humoral and cell mediated (CMI) responses, as well as durable immun ...
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 11

 TERMINÉ 

European Clearing House for Open Robotics Development Plus Plus (ECHORD Plus Plus)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2018,

Description ECHORD++ will create new opportunities for European robotics researchers to work directly with SME/start-ups and new users/customers to create innovative products. ECHORD++ will continue ECHORD’s two pillars, “experiments” and “structured dialogue”, taking advantage of experience and investment in the infrastructure. In addition, ...
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 68

 TERMINÉ 
Rapidly developing markets such as green construction, energy harvesting and storage, advanced materials for aerospace, electronics, medical implants and environmental remediation are potential key application targets for nanomaterials. There, nanotechnology has the potential to make qualitative improvements or indeed even to enable the technology. Impacts range from increased efficiency of energy ...
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 26

 TERMINÉ 

European Lead Factory (EUC²LID)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,

The European Lead Factory concept proposed by the EUC2LID Consortium relates to the discovery of novel small molecule candidates to serve as starting points for subsequent optimization to either drug candidates or high-quality pharmacological tools for the experimental validation of targets. The concept intends to bridge academic and applied research interests. The European Lead Factory will provi ...
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 34

 TERMINÉ 

Kinetics for Drug Discovery (K4DD) (K4DD)

Date du début: 1 nov. 2012, Date de fin: 31 oct. 2017,

There is mounting evidence that the often ignored kinetic aspects of the interaction between a drug and its target are highly relevant for clinical success. This ignorance may be one of the reasons for the high attrition rates in drug discovery, as it has been analyzed that many recently marketed drugs had indeed improved kinetic profiles. This hindsight knowledge needs to be converted into data-d ...
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 21

 TERMINÉ 
Currently the aerobic bio-catalytic oxidation reaction is the one that would have the biggest impact on the future uptake of industrial biotechnology in Europe. Chemical oxidation is both hazardous and has high environment impacts. Many oxidative bio-catalytic reactions and transformations have been identified in academic laboratories but only a very small number have been applied by industry to o ...
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 12

 TERMINÉ 

Resilience-Increasing Strategies for Coasts - toolKIT (RISC-KIT)

Date du début: 1 nov. 2013, Date de fin: 30 avr. 2017,

"Resilience-Increasing Strategies for Coasts – toolKIT (RISC-KIT) will deliver ready-to-use methods, tools and management approaches to reduce risk and increase resilience to low-frequency, high-impact hydro-meteorological events. The open-source and free-ware RISC-KIT tool kit will consist of ● a Coastal Risk Assessment Framework (CRAF) which - at the regional scale (100’s km) - can quickly asses ...
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 18

 TERMINÉ 

VPH Dementia Research Enabled by IT (VPH-DARE@IT)

Date du début: 1 avr. 2013, Date de fin: 31 mars 2017,

The DementiA Research Enabled by IT project responds to the European Parliament's 2011 resolution for a European Initiative on Alzheimer's disease and other dementias, and the EU Year of the Brain 2014 Initiative. It delivers the first patient-specific predictive models for early differential diagnosis of dementias and their evolution. Its mechanistic/phenomenological models of the ageing brain ac ...
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 22

 TERMINÉ 

European Patients' Academy on Therapeutic Innovation (EUPATI)

Date du début: 1 févr. 2012, Date de fin: 31 janv. 2017,

"The proposed project ""European Patients' Academy on Therapeutic Innovation"" (EUPATI) contributes to IMI’s goal of raising patients’ awareness and participation in pharmaceutical R&D. This patient-led academy will provide scientifically reliable, objective, comprehensive information to patients on pharmaceutical R&D. It will increase the capacity of well-informed patients to be effective advocat ...
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 33

 TERMINÉ 

Collaborating Smart Solar-powered Micro-grids (CoSSMic)

Date du début: 1 oct. 2013, Date de fin: 31 déc. 2016,

When considering renewable energy sources, like solar electricity, people often do not directly see the benefit of their investment. While the sun is shining and might be producing electricity in their homes, they are at their work and cannot use that energy directly, while when they need the energy at night (for laundry, lighting, computers) the solar panel is no longer producing. Indeed, researc ...
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 9

 TERMINÉ 
Prospective global supply and demand for gallium, indium and other key metals show an increasing discrepancy, amongst others due to the explosive growth of green technologies such as photovoltaics (PV) and solid-state lighting (SSL). While their primary production is highly controlled by a few countries, recycling systems to reclaim these materials from discarded products are not yet in place. Thi ...
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 12

 TERMINÉ 

European Medicines Research Training Network (EMTRAIN)

Date du début: 1 oct. 2009, Date de fin: 30 sept. 2016,

EMTRAIN is an essential element for the success of the IMI Education & Training (E&T) Call Topics in Europe (current and future). It will establish a pan-European platform of excellence for education and training covering the whole life-cycle of medicines from basic research through clinical development to pharmaco-vigilance. It will underpin the successful delivery of the current and future IMI-f ...
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 32

 TERMINÉ 

Drug Disease Model Resources (DDMORE)

Date du début: 1 mars 2011, Date de fin: 31 août 2016,

Model based-drug development (MBDD) is accepted as a vital approach in understanding patient risk/benefit and attrition. At the core of MBDD lies Modelling and Simulation (M&S), a technology providing the basis for informed, quantitative decision-making.M&S facilitates the continuous integration of available information related to a drug or disease into constantly-evolving mathematical models capa ...
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 28

 TERMINÉ 
The All-Electric Aircraft is a major target for the next generation of aircraft to lower consumption of non-propulsive power and thus fuel burn. To eliminate hydraulic circuits, pumps and reservoirs, Electro Mechanical Actuators (EMA) are mandatory but now need to meet cost, reliability and weight requirements from the airframers.ACTUATION2015 aims to develop and validate a common set of standard ...
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 56

 TERMINÉ 

EUROPEAN NETWORK for CANCER research in CHILDREN and ADOLESCENTS (ENCCA)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2015,

"ENCCA aims to establish a durable, European Virtual Institute clinical and translational research in childhood and adolescent cancers that will define and implement an integrated research strategy and will facilitate the necessary investigator-driven clinical trials to introduce the new generation of biologically targeted drugs into standard of care for children and adolescents with cancer. This ...
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 34

 TERMINÉ 
The growing share of electricity generation from intermittent renewable energy sources as well as increasing market-based cross border flows and related physical flows are leading to rising uncertainties in transmission network operation. In the mainland central Europe synchronous area due to large installations of renewable energy generation such as wind and photovoltaic, the difference between a ...
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 16

 TERMINÉ 

TRANSLATIONAL RESEARCH AND PATIENT SAFETY IN EUROPE (TRANSFoRm)

Date du début: 1 mars 2010, Date de fin: 30 nov. 2015,

TRANSFoRm will develop rigorous, generic methods for the integration of Primary Care clinical and research activities, to support patient safety and clinical research via:1.\tRich capture of clinical data, including symptoms and signs rather than just a single diagnosis. A generic, dynamic interface, integrated with electronic health records (EHR), will facilitate both diagnostic decision support ...
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 25

 TERMINÉ 
The installation of sprinklers can result in substantial reductions in insurance premiums and so insurance companies are becoming increasingly interested in their proper installation and function. For example, the British Automatic Fire Sprinkler Association has abundant evidence about the effectiveness of their members’ technology in reducing loss of life and property in office, residential, reta ...
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 10

 TERMINÉ 
READY4SmartCities operates in a European context where other initiatives are currently running in order to create a common approach on Smart Cities, Such initiatives, even if of fundamental importance for the EU, have some relevant gaps not allowing them to fully cover fundamental aspects for Smart Cities, i.e. to define a common data framework allowing full interoperability among different city s ...
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 11

 TERMINÉ 

Unbiased Biomarkers for the Prediction of Respiratory Disease Outcomes (U-BIOPRED)

Date du début: 1 oct. 2009, Date de fin: 30 sept. 2015,

RationaleThe inability of pre-clinical studies to predict clinical efficacy is a major bottleneck in drug development. In severe asthma this bottleneck results from: a lack of useful and validated biomarkers, underperforming pre-clinical models, inadequate and incomplete sub-phenotyping, and insufficient disease understanding.HypothesisThe use of biomarker profiles comprised of various types of hi ...
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 42

 TERMINÉ 

Smart Intelligent Aircraft Structures (SARISTU)

Date du début: 1 sept. 2011, Date de fin: 31 août 2015,

The project proposal concerns the challenges posed by the physical integration of smart intelligentstructural concepts. It addresses aircraft weight and operational cost reductions as well as animprovement in the flight profile specific aerodynamic performance.This concerns material concepts enabling a conformal, controlled distortion of aerodynamicallyimportant surfaces, material concepts enablin ...
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 68

 TERMINÉ 
Worm infections are receiving increased attention due to: the wide geographic overlap in occurrence between worms and HIV, TB and malaria; the large proportion of individuals (minimal estimates around 25%) co-infected with worms and HIV/TB/ malaria; the potential risk of increasing disease burden; the very limited understanding of the impact by worm infections on HIV-, TB- and malaria-specific imm ...
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 23

 TERMINÉ 
MARCAR aims to establish reliable early markers and molecular classification of tumors in non genotoxic carcinogenesis, applying a mechanism-based approach. Benefits are improved drug safety, more efficient drug development, and progress with 3 R issues. MARCAR focuses on rodent liver, the major target organ of non-genotoxic carcinogens (NGC). However, this approach will facilitate predictions for ...
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 12

 TERMINÉ 

Semantic Interoperability for Health Network (SemanticHealthNet)

Date du début: 1 déc. 2011, Date de fin: 31 mai 2015,

SemanticHealthNet will develop a scalable and sustainable pan-European organisational and governance process for the semantic interoperability of clinical and biomedical knowledge, to help ensure that EHR systems are optimised for patient care, public health and clinical research across healthcare systems and institutions.Through a clinically-driven workplan, exemplified in cardiovascular medicine ...
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 18

 TERMINÉ 
In 2020, mobile and wireless traffic volume is expected to increase thousand-fold over 2010 figures. Moreover, an increase in the number of wirelessly-connected devices to counts in the tens of billions will have a profound impact on society. Massive machine communication, forming the basis for the Internet of Things, will make our everyday life more efficient, comfortable and safer, through a wid ...
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 24

 TERMINÉ 
In all industrial sectors, Non Destructive Evaluation techniques play a critical role for ensuring structures reliability, plant safety and increasingly also for ensuring quality and efficiency of products and processes. The emerging use of numerical simulation is a major trend in the field with tremendous potential benefits in terms of costs reduction, enhanced diagnosis reliability and consequen ...
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 20

 TERMINÉ 

Alliance Permanent Access to the Records of Science in Europe Network (APARSEN)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2014,

Description Digital preservation offers the economic and social benefits associated with the long-term preservation of information, knowledge and know-how for re-use by later generations. However, digital preservation has a great problem, namely that preservation support structures are built on projects which are short lived and is fragmente ...
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 33

 TERMINÉ 

GEOSS interoperability for Weather, Ocean and Water (GEOWOW)

Date du début: 1 sept. 2011, Date de fin: 31 août 2014,

GEOWOW (GEOSS Interoperability for Weather, Ocean and Water) is the responds to call ENV.2011.4.1.3-1 Inter-operable integration of shared Earth Observations in the Global Context.The objectives of GEOWOW are to:• Propose and validate a distributed architectural model federating Earth observation and other Earth Science data holdings, including specific communities’ infrastructures, and put this m ...
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 15

 TERMINÉ 
Scope and background of projectIn the 4th call of the European FCH JU (AIP 2011) a project has been called to map out the relevance of hydrogen underground storage. The focus being on seasonal energy storage at large scale, the potential, application profile, impact of and schedule to implement this concept may differ across Europe. In recent studies a clear profile for various large-scale storage ...
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 12

 TERMINÉ 

Printable, organic and large-area realisation of integrated circuits (POLARIC)

Date du début: 1 janv. 2010, Date de fin: 30 juin 2014,

The objective of the project is to realise high-performance organic electronic devices and circuits using large-area processing compatible fabrication methods. The high performance of the organic circuits referred to here means high speed (kHz-MHz range), low parasitic capacitance, low operating voltage, and low power consumption. The related organic thin film transistor (OTFT) fabrication develop ...
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 15

 TERMINÉ 

PREPARED “ENABLING CHANGE” (PREPARED)

Date du début: 1 févr. 2010, Date de fin: 31 janv. 2014,

IPCC climate change scenarios have a global perspective and need to be scaled down to the local level, where decision makers have to balance risks and investment costs. Very high investments might be a waste of money and too little investment could result in unacceptable risk for the local community. PREPARED is industry driven, 12 city utilities are involved in the project and the RDT carried out ...
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 36

 TERMINÉ 

Threedimensional Adaptive Camera with Object Detection and Foveation (TACO)

Date du début: 1 févr. 2010, Date de fin: 31 juil. 2013,

Description Giving robots faster, more human-like vision through foveationTACO develops a 3D sensing system with 3D foveation properties endowing service robots with a higher level of motion and affordance perception and interaction capabilities with respect to everyday objects and environments in a more natural and human-like manner. The ...
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 7

 TERMINÉ 
"SUNJET is a European Project within the Framework Programme 7 (Research / Aeronautics and Air Transport) aiming at establishing an initial framework, data base and network, in order to facilitate and enhance the cooperation in R&T activities between Japan and Europe. Through the participation of all the relevant Stakeholders, it will introduce a more structured dialogue to identify the similariti ...
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 7

 TERMINÉ 
"The electric ship concept offers many benefits; among other aspects if offers flexibility of control and effectiveness of power transmission. But predominantly it enables higher energy conversion efficiency by ensuring that prime movers are effectively loaded at all times and across all operating conditions. This dominating advantage cannot be matched by mechanical transmission systems because ge ...
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 34

 TERMINÉ 
Prosys-Laser is dedicated to develop highly innovative “passive” and “active” laser protective clothing for the use with hand-held laser processing devices (HLD), which are not available on the market today. Major project objectives are: a) Open new markets for high performance PPE and its testing, especially enforcing participating SME to widen their product range and directly benefit from projec ...
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 15

 TERMINÉ 

Ultrasmall MEMS FTIR Spectrometer (MEMFIS)

Date du début: 1 sept. 2008, Date de fin: 29 févr. 2012,

MEMFIS plans to show the feasibility of a miniature spectroscopic chemical sensor system based on a micro-FT-IR spectrometer. Based on mid-infrared spectroscopy offering analyte selectivity unrivalled by any other method and paired with the inherent sensitivity of a FT-IR spectrometer, such devices could be used in a wide range of applications, from air monitoring over in-line real-time process co ...
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 10

 TERMINÉ 
"Distributors and promoters of organic food claim their products are superior in taste compared to conventional alternatives. This argument, however, is still the subject of heated debate and thus deserves greater scientific examination. Since repurchase intentions are dependent on the overall liking of a product, and sensory experiences may have an important impact on this, knowledge about these ...
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 23

 TERMINÉ 
The call 4.2.2-1 “organic materials for electronics and photonics” is based on the observation that the limited availability of high-performance multi-functional materials is a roadblock to further industrial progress. To address the wide scope of the call, we have identified specific materials bottlenecks to the fields of electronics and photonics. They constitute the focal points of our project. ...
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 31

 TERMINÉ 
"The disease threats to the livestock industry have increased steadily over the past decades as a result of globalisation, evolving pathogens and climate change. Responding to animal disease threats relies heavily on science; research makes a significant contribution to the development of disease control policy and the translation of policy, and other drivers for improving animal health, into prac ...
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 29

 TERMINÉ 

E-SCIENCE GRID FACILITY FOR EUROPE AND LATIN AMERICA (EELA-2)

Date du début: 1 avr. 2008, Date de fin: 31 mars 2010,

EELA-2 aims to build, on the current EELA e-Infrastructure, a high capacity, production-quality, scalable Grid Facility providing round-the-clock, worldwide access to distributed computing, storage and network resources for a wide spectrum of applications from European and Latin American scientific communities. The project will provide an empowered Grid Facility with versatile services fulfilling ...
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 56