14 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Towards enduring mouse resources and services advancing research into human health and disease (INFRAFRONTIER2020)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
The INFRAFRONTIER RI integrates European Mouse Clinics and the European Mouse Mutant Archive with the common goal to ensure access to mouse models for basic research of human health and disease, and to translate this knowledge into therapeutic approaches for the benefit of the European society. The expanded INFRAFRONTIER2020 network, coordinated by the INFRAFRONTIER GmbH, includes 3 SMEs and is st ...
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33
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TERMINÉ
HARMONIzation and integrative analysis of regional, national and international Cohorts on primary Sjögren’s Syndrome (pSS) towards improved stratification, treatment and health policy making (HarmonicSS)
Date du début: 1 janv. 2017, Date de fin: 30 juin 2020,
HarmonicSS vision is to create an International Network and Alliance of partners and cohorts, entrusted with the mission of addressing the unmet needs in primary Sjogren Syndrome; working together to create and maintain a platform with open standards and tools, designed to enable secure storage, governance, analytics, access control and controlled sharing of information at multiple levels along wi ...
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39
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TERMINÉ
Dobutamine for NEOnatal CIRCulatory failure defined by novel biomarkers (NEO-CIRC)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2018,
Dobutamine and adrenaline are widely used as second line therapy for systemic hypotension in infants. Dopamine is currently the most widely used first line drug. In neonates, sustained hypotension may, and impaired organ perfusion will, cause brain injury and poor neurodevelopmental outcomes. All three catecholamines are currently used off-label and have different modes of action which may result ...
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20
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TERMINÉ
Stem cells for Biological Assays of Novel drugs and prediCtive toxiCology (StemBANCC) (STEMBANCC)
Date du début: 1 oct. 2012, Date de fin: 30 sept. 2017,
StemBANCC, comprising internationally renowned investigators, is ideally positioned to deliver a unique European biorepository and drug discovery pipeline based upon human induced pluripotent stem cells (hiPSC). This unrivalled opportunity will address the pressing therapeutic need in neurodegeneration, neurodysfunction and diabetes. We have immediate access to richly phenotyped subjects with a we ...
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38
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TERMINÉ
International study for treatment of childhood relapsed ALL 2010 with standard therapy, systematic integration of new agents, and establishment of standardized diagnostic and research (INTREALL)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2016,
Though survival of children with acute lymphoblastic leukaemia (ALL) has improved, relapse remains a leading cause of mortality in childhood cancer. Given the rarity of the disease, only a large international cooperative group can recruit sufficient patients for prospective studies with specific questions in biologic subgroups. Under the umbrella of the I-BFM SG all relevant mainly European study ...
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29
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TERMINÉ
Development of novel treatment strategies based on knowledge of cellular dysfunction in diabetes (BetaBat)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2015,
A reduction in functional pancreatic beta cell mass is the key feature of type 1 and type 2 diabetes. Beta cell failure is exacerbated in the context of obesity and insulin resistance. Brown adipose tissue (BAT) is a highly metabolic organ, mediating energy dissipation and glucose disposal, thus contributing to maintain energy balance. BAT dysfunction contributes to obesity and impaired glucose me ...
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12
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TERMINÉ
Minimizing Defects in Micro-Manufacturing Applications (MIDEMMA)
Date du début: 1 nov. 2011, Date de fin: 31 oct. 2014,
Micro-manufacturing requires 'Zero-Defect' oriented approaches, both in large scale and in short-run production. Current quality control approaches, coming from macro-manufactring, are mainly based on post-process geometric control, which produces a large time lag between the defect generation and its detection, usually leading to large amount of defect parts (large scale) or wasted high value pro ...
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18
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TERMINÉ
A NEXT-GENERATION, SECURE LINKED DATA MEDICAL INFORMATION SPACE FOR SEMANTICALLY-INTERCONNECTING ELECTRONIC HEALTH RECORDS AND CLINICAL TRIALS SYSTEMS ADVANCING PATIENTS SAFETY IN CLINICAL RESEARCH (Linked2Safety)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2014,
The vision of the proposed Linked2Safety project is to advance clinical practice and accelerate medical research, to improve the quality of healthcare, benefiting public health, and to enhance patients' safety; by providing pharmaceutical companies, healthcare professionals and patients with an innovative semantic interoperability framework, a sustainable business model, and a scalable technical i ...
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13
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TERMINÉ
International Research on Quality in Healthcare (InterQuality)
Date du début: 1 déc. 2010, Date de fin: 30 avr. 2014,
International Research Project on Financing Quality in Healthcare InterQuality gathers the interest for financing systems' effect on quality of healthcare of researchers from seven EU countries and US. The study, based on administrative and survey data, is designed for 36 months. It will take into account needs of four different patient groups (sectors), affected by: hospital, outpatient, pharmace ...
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10
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TERMINÉ
Studies Investigating Co-morbidities Aggravating Heart Failure (SICA-HF)
Date du début: 1 oct. 2009, Date de fin: 31 mars 2014,
"Chronic heart failure (CHF) is a massive clinical, social and economic problem. Diabetes and obesity increase the risk of developing CHF. Cachexia is also an ominous sign. In 13 clinical and preclinical research projects, SICA-HF aims to investigate the impact of these co-morbidities in CHF patients at the clinical, vascular, cellular and molecular levels. SICA-HF will enrol >1600 patients wit ...
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13
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TERMINÉ
Embryonic Stem cell-based Novel Alternative Testing Strategies (ESNATS)
Date du début: 1 avr. 2008, Date de fin: 30 sept. 2013,
"ESNATS aims at developing a novel toxicity test platform based on embryonic stem cells (ESC), especially human ESC (hESC), to accelerate drug development, reduce R&D costs and propose a powerful alternative to animal tests (3 Rs). ESNATS will address current drug-testing shortcomings: - testing takes place late in the development cycle - animal test systems bear the risk of non-prediction due to ...
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34
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TERMINÉ
... the lymphatic vessels have a high incidence but are poorly understood, as they are the subject of little research. The lymphatic system and its diseases are seldom mentioned during the undergraduate medical curriculum. There is also a lack of postgraduate training in lymphology for medical doctors. However, diseases of the lymphatics have a high incidence. In developed countries around 20-50% of ...
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8
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TERMINÉ
The global impact of serious environmental problems is increasingly conscious for companies and employees. But despite all regulations and economic incentives, the main issue is a lack of coherent ideology surrounding organisational and corporate responses. Particularly environmental ethics could bring a significant contribution, to create the necessary awareness about the increasing responsibilit ...
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7
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TERMINÉ
The aim of the project was to align EU countries to provide standardised, accredited training for HCPs, and create transferable learning outcomes and credit points. The objective was to identify barriers and facilitators for the creation of the curriculum; to develop an EU accredited Certified Diabetes Educator Course (EU-CDEC) and establish an accreditation process aligned to ECVET principles. Th ...
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