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TERMINÉ
ROLE OF CYCLOPHILIN A IN BONE MARROW VASCULAR PROGENITOR CELL MOBILIZATION AND RECRUITMENT IN THE ANGIOGENIC RESPONSE TO ISCHEMIA (CAPI)
Date du début: 1 janv. 2012, Date de fin: 3 juin 2016,
"Critical limb ischemia (CLI) is a major health problem; it affects approximately three million people in Western Europe, its prevalence is increasing, adequate medical treatment is not available, and patients with advanced disease are usually unsuitable for revascularization procedures. Since CLI is characterized by inadequate tissue vascularization, much effort has been focused on strategies aim ...
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TERMINÉ
NUCLEOLAR-DEPENDENT SECRETION OF MICRORNA IN A MODEL OF DOXORUBICIN AND TRASTUZUMAB CARDIOMYOPATHY (NUMIRDT)
Date du début: 1 sept. 2011, Date de fin: 31 août 2015,
"Combination of Doxorubicin (Dox) and the monoclonal antibody trastuzumab (Trz) is being effectively used against breast cancer, but associated with high incidence of cardiotoxicity. The mechanisms of Dox+Trz induced synergic cardiotoxicity are still unclear. Recently the activation of the microRNA 146a has been shown to have a role in the synergistic effect of Dox and Trz cardiotoxicity. MicroRNA ...
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