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27 projets européens trouvés

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 TERMINÉ 

Attention Deficit Hyperactivity Disorder Drugs Use Chronic Effects (ADDUCE)

Date du début: 1 nov. 2010, Date de fin: 30 avr. 2016,

Attention deficit hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders in children, affecting approximately 5% children in Europe. Methylphenidate (MPH) is the most-commonly prescribed medication for ADHD children; it is also increasingly used in ADHD adults. In 2007, the European Commission requested a referral to the Committee for Medicinal Products for Human Use ...
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 17

 TERMINÉ 

Treatment of NEonatal seizures with Medication Off-patent: evaluation of efficacy and safety of bumetanide (NEMO)

Date du début: 1 oct. 2009, Date de fin: 31 mars 2015,

Neonatal hypoxic ischaemic encephalopathy (HIE) occurs in 2-3/1000 live births and is a major cause of both acute mortality and long-term neurodisability. Seizures are the hallmark of HIE. The clinical and electrographic seizure burden in babies with HIE can be considerable and is often not reduced by current antiepileptic drugs. Phenobarbitone remains the first line drug for neonatal seizures des ...
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 15

 TERMINÉ 

Public Engagement with Research and Research Engagement with Society (PERARES)

Date du début: 1 mai 2010, Date de fin: 31 oct. 2014,

PERARES strengthens public engagement in research (PER) by developing multi-annual action plans, involving researchers and Civil Society Organisations (CSOs) in the formulation of research agendas and the research process. It uses debates on science to actively articulate research requests of civil society. These are forwarded to research institutes, and results are used in a next phase of the deb ...
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 28

 TERMINÉ 

Marine Renewable Integrated Application Platform (MARINA Platform)

Date du début: 1 janv. 2010, Date de fin: 30 juin 2014,

MARINA is a European project dedicated to bringing offshore renewable energy applications closer to the market by creating new infrastructures for both offshore wind and ocean energy converters. It addresses the need for creating a cost-efficient technology development basis to kick-start growth of the nascent European marine renewable energy (MRE) industry in the deep offshore – a major future gl ...
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 18

 TERMINÉ 

Valorizing Andean microbial diversity through sustainable intensification of potato-based farming systems (VALORAM)

Date du début: 1 févr. 2009, Date de fin: 31 janv. 2014,

VALORAM aims at exploring and valorizing Andean soil microbial diversity for the development of alternative, efficient technologies and crop management practices to improve the sustainability and productivity of Andean cropping systems benefiting rural farming households. The project will focus on potato because of its global importance for small-scale farmers in the central Andean highlands. The ...
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 8

 TERMINÉ 

Integration of European Simulation Chambers for Investigating Atmospheric Processes - Part 2 (EUROCHAMP-2)

Date du début: 1 mai 2009, Date de fin: 31 déc. 2013,

"The fundamental objective of the project is the further integration of existing European research facilities to a grid of reaction chambers in a continuation of the EUROCHAMP project. These facilities were created to study the impact of atmospheric processes e.g. on regional photochemistry, global change, as well as cultural heritage and human health effects under as realistic conditions as possi ...
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 14

 TERMINÉ 

Investigation of the Regulation of Toll-like Receptor Mediated Transcription (TLR Tolerance)

Date du début: 1 déc. 2009, Date de fin: 30 nov. 2013,

Toll-like receptors (TLRs) are key microbial sensors essential for the development of innate immunity to pathogens[1]. TLR activation induces the expression of inflammatory cytokines, antimicrobial proteins, and regeneration factors. Uncontrolled activation of TLRs leads to the development of fatal inflammatory diseases. TLR activation is tightly controlled to ensure that repeated activation does ...
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 2

 TERMINÉ 

Monitoring and Evaluation of Spatially Managed Areas (MESMA) (MESMA)

Date du début: 1 nov. 2009, Date de fin: 31 oct. 2013,

The increasing pressures upon the marine realm call for a well planned approach of further spatial development of this area. An ecosystem-based approach to fisheries, the increasing demand for sustainable energy, coastal defence systems, building materials and safe transport routes and the need to protect marine habitats and species all compete for the same valuable space. At the same time climate ...
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 22

 TERMINÉ 

Establishing the scientific bases and technical procedures and standards to recover the European flat oyster production through strategies to tackle the main constraint, bonamiosis (OYSTERECOVER)

Date du début: 1 mai 2010, Date de fin: 31 oct. 2013,

The European flat oyster, has been part of the human diet for many centuries. High mortality episodes and overfishing decimated the populations of O.edulis in Europe through the first half of the XXth century. Then, two diseases (due to Marteilia refringens and Bonamia ostreae) spread in the early 1970s and 1980s, drastically reducing the production. Despite new management practices, and intensive ...
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 16

 TERMINÉ 

Investigating Trib2-induced Acute Myeloid Leukaemia (Trib2 in AML)

Date du début: 1 oct. 2009, Date de fin: 30 sept. 2013,

Acute Myeloid Leukemia (AML) is a poorly treatable leukemia in which a limited set of genes are involved. Trib2 is a gene that has not previously been associated with leukemia. My goal is to understand the pathogenesis of Trib2-induced acute myelogenous leukemia (AML). I identified Trib2 as a novel leukomogen that efficiently induces a clonal, transplantable AML in mice. Trib2 inhibits C/EBPalpha ...
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 2

 TERMINÉ 

Knowledge-based Sustainable Management for Europe's Seas (KnowSeas)

Date du début: 1 avr. 2009, Date de fin: 30 juin 2013,

Europe’s four regional seas (Baltic, Black, Mediterranean and NE Atlantic) have suffered severe environmental degradation due to human pressure. Existing measures to manage pressures have proven inadequate and the EC has responded by proposing a new policy (Maritime Strategy Blue Book) and environmental legislation (Marine Strategy Directive), both currently close to adoption. These instruments re ...
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 34

 TERMINÉ 

Interaction in coastal waters: A roadmap to sustainable integration of aquaculture and fisheries (COEXIST)

Date du début: 1 avr. 2010, Date de fin: 30 juin 2013,

"Coastal areas are subject to an increase in competing activities and protection (Natura 2000, Marine Strategy Directive) and are a source of potential conflict for space allocation. COEXIST is a broad, multidisciplinary approach to evaluate these interactions with the ultimate goal to provide a roadmap to better integration, sustainability and synergies among different activities in the coastal z ...
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 14

 TERMINÉ 

Facilitating Implementation of Research Evidence (FIRE)

Date du début: 1 janv. 2009, Date de fin: 30 juin 2013,

Facilitating Implementation of Research Evidence (FIRE) is a proposed four year programme of research to identify and validate key factors determining the successful implementation of research evidence in practice. The study is underpinned by a conceptual framework, the Promoting Action on Research Implementation in Health Services (PARiHS) framework, which proposes that the successful implementat ...
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 8

 TERMINÉ 

Bio-engineered micro Encapsulation of Active agents Delivered to Shellfish (BEADS)

Date du début: 1 mars 2011, Date de fin: 31 mai 2013,

"The project aims to continue with some exciting work following up a development in delivering active agents to bivalve molluscs through micro-encapsulation. The early work showed that bacteria with a potential in vitro to break down some algal toxins could be effectively delivered to the gut of the bivalve. The size and nature of the micro-capsule (bead) was shown to be key. The SMEs and Other in ...
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 12

 TERMINÉ 

Pan-European infrastructure for management of marine and ocean geological and geophysical data (Geo-Seas)

Date du début: 1 mai 2009, Date de fin: 31 janv. 2013,

The overall objective of the Geo-Seas project is to effect a major and significant improvement in the overview and access to marine geological and geophysical data and data-products from national geological surveys and research institutes in Europe by upgrading and interconnecting their present infrastructures.The Geo-Seas partnership has taken a strategic decision to adopt the SeaDataNet interope ...
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 31

 TERMINÉ 

Open service network for marine environmental data (NETMAR)

Date du début: 1 févr. 2010, Date de fin: 31 janv. 2013,

NETMAR aims to develop a pilot European Marine Information System (EMIS) for searching, downloading and integrating satellite, in situ and model data from ocean and coastal areas. It will be a user-configurable system offering service discovery, access and chaining facilities using OGC, OPeNDAP and W3C standards. It will use a semantic framework coupled with ontologies for identifying and accessin ...
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 7

 TERMINÉ 

Tasty and healthy gluten-free bakery products and pasta - improved products for wide consumer acceptance (GlutenFree)

Date du début: 1 oct. 2010, Date de fin: 31 déc. 2012,

Currently two per cent of European consumers are suffering from coeliac disease that demands a strict gluten-free diet. Gluten is part of all common cereals and therefore contained in basic foodstuffs like bakery products and pasta. The market for gluten-free products, which is predominately served by small and medium sized enterprises (SMEs), showed considerable growth in the last years. However, ...
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 11

 TERMINÉ 

Epistemology and Democracy in Complex Societies (EPIDEMICS) (EPIDEMICS)

Date du début: 1 janv. 2010, Date de fin: 31 déc. 2012,

"It is often said that the sciences should be brought into democracy (EC 2000), but conceptual frameworks for making sense of that aspiration are surprisingly underdeveloped. There is a now a wealth of middle-range theoretical and empirical research on new democratic institutional innovations addressing themes such as genetic modification, biosecurity, reproductive technologies and genetic testing ...
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 1

 TERMINÉ 

Flexible Wood Supply Chain (FlexWood)

Date du début: 1 nov. 2009, Date de fin: 31 oct. 2012,

A number of studies indicate that the market demand for wood will lead to strong competition between the different wood industry branches. This is especially true in view of a globalised wood market, in which production is characterised by fast structural changes and concentration processes. Competition between different wood industries and the development towards large production units, as well a ...
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 15

 TERMINÉ 

Hotspot Ecosystem Research and Man's Impact on European seas (HERMIONE)

Date du début: 1 avr. 2009, Date de fin: 30 sept. 2012,

The HERMIONE project is designed to make a major advance in our knowledge of the functioning of deep-sea ecosystems and their contribution to the production of goods and services. This will be achieved through a highly interdisciplinary approach (including biologists, ecologists, microbiologists, biogeochemists, sedimentologists, physical oceanographers, modelers and socio-economists) that will in ...
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 41

 TERMINÉ 

Serotonin and GABA-B receptors in anxiety : from developmental risk factors to treatment (DEVANX)

Date du début: 1 févr. 2008, Date de fin: 31 juil. 2012,

"GABAergic and serotoninergic systems are key players in the control of anxiety states but the precise bases for their action has remained elusive. New findings, brought about by members of this consortium, are radically changing our views on the neurobiological action of these two transmitters and will be the focus of the present proposal. The first original dimension is the discovery of a develo ...
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 8

 TERMINÉ 

A PHArmacogenomic study of Statins in the Elderly at risk for cardiovascular disease (PHASE)

Date du début: 1 janv. 2009, Date de fin: 30 juin 2012,

"Cardiovascular disease is the leading cause of death in industrialized countries. The prevention of cardiovascular disease is critically dependent on lipid lowering therapy, which includes the 3-hydroxymethyl-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins). Although statins are the most prescribed class of drugs worldwide, and therapy is generally associated with a reduction ...
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 4

 TERMINÉ 

Track-etched Single Nanopores: Advanced Characterisation and New Applications (Nano-ChApp)

Date du début: 1 juil. 2009, Date de fin: 30 juin 2012,

This fellowship aims to develop the career of the researcher to the point where he is in a very strong position to start his own research group and secure funding to do so. This will be achieved by complementing his existing scientific knowledge to give him a broad and well rounded-expertise on nanopore fabrication, characterisation and applications, giving him training in complementary skills suc ...
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 2

 TERMINÉ 

European Patient Organizations in Knowledge Society (EPOKS)

Date du début: 1 févr. 2009, Date de fin: 30 avr. 2012,

"The last two decades have witnessed the increasing role of patient, user and civil society organizations (POs and CSOs) in the production of knowledge on diseases and health problems. Rich and detailed studies have shown that this phenomenon entails new forms of activism. It also questions the modes of governance of knowledge, as well as the role of knowledge in the governance of health and medic ...
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 5

 TERMINÉ 

Performance Control in Wireless Sensor Networks (GINSENG)

Date du début: 1 sept. 2008, Date de fin: 29 févr. 2012,

Research on wireless sensor networks (WSNs) is at an early stage and, to date, practical experience with deployment has been very limited. The focus of past research has been on fundamental design issues, especially on optimizing the use of scarce energy resources in battery-powered devices. Published studies show relative comparisons between alternative approaches, but there has been a dearth of ...
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 10

 TERMINÉ 

IBD: proteases offer new targets for drug discovery (IPODD)

Date du début: 1 juin 2008, Date de fin: 31 mai 2011,

"The inflammatory bowel diseases (IBD) which comprise Crohn’s disease and ulcerative colitis are chronic relapsing and remitting inflammatory disorders of the gastrointestinal tract. The frequency of these conditions has increased in recent decades, particularly in countries making the transition from developing to developed nation status. In western Europe, IBD now affects between 1/1000 and 5/10 ...
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 12

 TERMINÉ 

E-SCIENCE GRID FACILITY FOR EUROPE AND LATIN AMERICA (EELA-2)

Date du début: 1 avr. 2008, Date de fin: 31 mars 2010,

EELA-2 aims to build, on the current EELA e-Infrastructure, a high capacity, production-quality, scalable Grid Facility providing round-the-clock, worldwide access to distributed computing, storage and network resources for a wide spectrum of applications from European and Latin American scientific communities. The project will provide an empowered Grid Facility with versatile services fulfilling ...
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 56