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 TERMINÉ 

Clonidine for Sedation of Paediatric Patients in the Intensive Care Unit (CloSed)

Date du début: 1 déc. 2013, Date de fin: 30 nov. 2018,

The majority of critically ill children admitted to Paediatric Intensive Care Units (PICU) will require sedation and analgesia which is commonly achieved with a combination of an benzodiazepine and an opioid. However, these agents have a significant side-effect profile, including tolerance, withdrawal and respiratory/circulatory depression. Clonidine is commonly used for sedation in PICU and recom ...
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 10

 TERMINÉ 

Labeling of Enalapril from Neonates up to Adolescents (LENA)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2018,

Children are often treated as small adults—not as the special patients they are. Regulations exist to encourage the development of drugs and formulation for children. However, off-patent drugs are often administered to children without appropriate formulations or systematic investigations. Therefore, the paediatric use marketing authorisation (PUMA) has been designed.The EMA Paediatric Working Par ...
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 14

 TERMINÉ 

Process Line Implementation for Applied Surface Nanotechnologies (PLIANT)

Date du début: 1 févr. 2013, Date de fin: 31 janv. 2017,

...t had insufficient information or could benefit from “upgrading” or justification. Our response and actions against each point raised has been summarized and send to the project officer, Dr. Rene Martins, in a separate document.
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 24

 TERMINÉ 
Quality assurance plays a key role in the food industry. Current control of safety and quality characteristics of the various products is carried out mainly by random sampling of the initial, intermediate and/or final products. However, this methodology does not allow immediate adjustments to the production process in case any negative quality features are detected and consequently large batches o ...
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 8

 TERMINÉ 
Traditional preclinical discovery methods, particularly for target validation, poorly predict drug efficacy, causing a high attrition rate in costly late-stage clinical trials. The PREDECT consortium will focus on complex but transferable, next generation in vitro and in vivo models for breast, prostate and lung cancers. Models will be investigated for their improved potential to validate novel th ...
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 23

 TERMINÉ 
NANOSIL Network of Excellence aims to integrate at the European level the excellent European research laboratories and capabilities in order to strengthen scientific and technological excellence in the field of nanoelectronic materials and devices for terascale integrated circuits (ICs) and disseminate the results in a wide scientific and industrial community.NANOSIL will explore and assess the sc ...
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