9 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Novel nanotechnology-enabled system for endovascular in vivo near-infrared fluorescence molecular imaging and endovascular near-infrared targeted photodynamic therapy of atherosclerotic heart disease (CosmoPHOS-nano)
Date du début: 1 mars 2013, Date de fin: 28 févr. 2018,
CosmoPHOS-nano is a multidisciplinary, translational and business-oriented project, aiming to accomplish the following objectives:1) develop the CosmoPHOS system, which is a novel theranostic (diagnostic & therapeutic) nanotechnology-enabled portable combination system enabling endovascular in vivo near-infrared fluorescence molecular imaging, endovascular near-infrared targeted photodynamic thera ...
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20
Participants partenaires
TERMINÉ
Nanotherapeutics for antibiotic resistant emerging bacterial pathogens (NAREB)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,
Increase in antibiotic resistance is a global concern worldwide. The project NAREB's main objective is the optimization of several nanoformulations of antibacterial therapeutics in order to improve the therapy of multi-drug resistant (MDR) tuberculosis (TB) and MRSA infections in European MDR patients.NAREB will address the problem of drug bioavailability inside the infected macrophages, transport ...
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16
Participants partenaires
TERMINÉ
Nanotherapeutics to Treat Antibiotic Resistant Gram-Negative Pneumonia Infections (PNEUMONP)
Date du début: 1 janv. 2014, Date de fin: 31 déc. 2017,
The main objective of PneumoNP is the development of a theragnostic system for the treatment of lung Gram-negative bacterial infections. As a proof of concept PneumoNP will focus the attention on Klebsiella pneumoniae caused infections. A diagnostic kit will be developed to enable a rapid and precise identification of the bacteria strain causing the infection and avoid the use of wide spectrum a ...
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11
Participants partenaires
TERMINÉ
Bioactivated hierarchical hydrogels as zonal implants for articular cartilage regeneration (HYDROZONES)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,
Degeneration of cartilage is a major cause of chronic pain, lost mobility and reduced quality of life for millions of European citizens. From a clinical point of view treatment to achieve cartilage regeneration (hyaline) and not only repair (fibrous) remains a great challenge. No clinical therapy is available that leads to healing of cartilage defects.Current cartilage implants cannot establish th ...
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18
Participants partenaires
TERMINÉ
Collaboration on the Optimisation of Macromolecular Pharmaceutical Access to Cellular Targets (COMPACT)
Date du début: 1 nov. 2012, Date de fin: 31 oct. 2017,
Most biopharmaceuticals (BP) currently on the market are recombinant proteins which are parenterally administered. These would benefit from more patient-friendly routes of administration. Moreover, new classes of BP (e.g. siRNA, miRNA, DARPins) with specificity for intracellular targets hold promise but await the advent of efficient delivery systems before their potential can be realised into ther ...
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22
Participants partenaires
TERMINÉ
Novel drug delivery system produced by centrifugal technologies – composed to minimize adverse immune reactions and designed for optimised therapeutic effects (decent AID)
Date du début: 1 avr. 2013, Date de fin: 31 mars 2017,
Drug delivery systems are a matter of intensive scientific investigation and technological developments. They are necessary since many active pharmaceutical ingredients to be employed in therapy, diagnostics or vaccination cause serious side effects when distributed non-specifically. Without a drug delivery system, the active pharmaceutical ingredients may accumulate in healthy and sensitive tissu ...
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4
Participants partenaires
TERMINÉ
Engineered nanomaterial mechanisms of interactions with living systems and the environment: a universal framework for safe nanotechnology (NANOMILE)
Date du début: 1 mars 2013, Date de fin: 28 févr. 2017,
The NanoMILE project is conceived and led by an international elite of scientists from the EU and US with the aim to establish a fundamental understanding of the mechanisms of nanomaterial interactions with living systems and the environment, and uniquely to do so across the entire life cycle of nanomaterials and in a wide range of target species. Identification of critical properties (physico-che ...
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30
Participants partenaires
TERMINÉ
Development & Evaluation of a Viable Stent Device for the Treatment of BronchoTracheal Cancer (PULMOSTENT)
Date du début: 1 avr. 2012, Date de fin: 31 mars 2015,
Lung cancer is the most common cancer in terms of both incidence and mortality, worldwide. With a median age at diagnosis of 71, lung cancer is mainly affecting the aging population. Airway stenosis is a key problem with significant morbidity and premature death. Endobronchial stenting is a proven therapy to keep the airways open. Nevertheless the currently used clinical stents have major disadvan ...
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8
Participants partenaires
TERMINÉ
Smart nanosystems for advanced cancer therapy (NanoSmart)
Date du début: 1 mars 2012, Date de fin: 28 févr. 2014,
Advances in the preparation of nanotechnology-based materials in medical science pose new challenges in the design of smart nanodevices capable of meeting clinical needs. These systems are called to solve the issues associated to a non-specific delivery of drugs, which lead to the failure of a large number of treatments for oncological diseases.A selective and safe carrier for drug delivery should ...
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