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19 projets européens trouvés

Recherche sur 125080 projets européens

 TERMINÉ 

Unrestricted Leveraging of Targets for Research Advancement and Drug Discovery (ULTRA-DD)

Date du début: 1 mars 2015, Date de fin: 29 févr. 2020,

ULTRA-DD (Unrestricted Leveraging of Targets for Research Advancement and Drug Discovery) will be an European-wide, highly collaborative and inclusive consortium, to validate new targets for drug discovery by (1) generating high quality research tools, with an emphasis on chemical probes; (2) generating the chemical probes in the most cost-effective manner, using structure-guided methods and harne ...
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 10

 TERMINÉ 

Cancer treatment and monitoring through identification of circulating tumour cells and tumour related nucleic acids in blood (CANCER-ID)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2019,

Blood-based biomarkers such as Circulating Tumor Cells (CTCs), circulating free tumor DNA (cfDNA) and microRNAs (miRNAs) have the potential to improve the development of personalized medicines for cancer patients. This is of particular importance when biopsies of the primary tumor or metastases are not accessible (e.g. at early disease stages or in minimal residual disease) or possible and the ass ...
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 34

 TERMINÉ 

Molecular Reclassification to Find Clinically Useful Biomarkers for Systemic Autoimmune Diseases (PRECISESADS)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,

We concur to the IMI on “Reclassification of SLE, connective tissue diseases and RA” call by presenting a proposal aimed at using the power of OMICs, and bioinformatics to identify new classifications for diseases known to share common pathophysiological mechanisms. Such knowledge has not been applied to individual patients, depriving them from potential benefits in terms of the use of new therape ...
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 30

 TERMINÉ 

Intelligent Assessment of Pharmaceutical in the Environment (IPIE)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,

Active pharmaceutical ingredients (APIs) can be released to the natural environment during the manufacturing process, following use by patients or when unused medicines are disposed of. As APIs are biologically active compounds concerns have been raised about the potential effects of APIs in the environment on human and environmental health. Over the past 15 years, a substantial amount of work has ...
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 29

 TERMINÉ 

European Lead Factory (EUC²LID)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,

The European Lead Factory concept proposed by the EUC2LID Consortium relates to the discovery of novel small molecule candidates to serve as starting points for subsequent optimization to either drug candidates or high-quality pharmacological tools for the experimental validation of targets. The concept intends to bridge academic and applied research interests. The European Lead Factory will provi ...
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 34

 TERMINÉ 

Sensing and integration of signals governing cell polarity and tropism in fungi (FUNGIBRAIN)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

"Cell polarity and directed growth (tropism) are fundamental biological processes. Most fungi are dependent on these processes because they grow as polarised filaments called hyphae, whose growth and developmentare governed by physical and chemical cues from the environment. Such cues include surface-contact, light, nutrients, mating partners, host organisms, or ‘self’ hyphae from within the fung ...
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 13

 TERMINÉ 

Oral biopharmaceutics tools (ORBITO)

Date du début: 1 oct. 2012, Date de fin: 30 sept. 2017,

The OrBiTo project will deliver novel methods and a framework for rational application of predictive biopharmaceutics tools for oral drug delivery. This will be achieved through novel propsective studies to define new methodlogies which will be validated using historical datasets from EFPIA partners. A combination of high quality in vitro or in silico characterizations of API and formulations will ...
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 28

 TERMINÉ 

Quantitative T cell Immunology (QuanTI)

Date du début: 1 mai 2013, Date de fin: 30 avr. 2017,

The primary objective of this ITN is to train a new generation of European quantitative immunologists, who will be able to address challenges arising in Systems Immunology. This will be achieved with the proposed Network, Quantitative T cell Immunology (QuanTI), that will train 11 ESRs and 4 ERs, bringing together renowned experimental and theoretical scientists from private and academic instituti ...
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 12

 TERMINÉ 

European Patients' Academy on Therapeutic Innovation (EUPATI)

Date du début: 1 févr. 2012, Date de fin: 31 janv. 2017,

"The proposed project ""European Patients' Academy on Therapeutic Innovation"" (EUPATI) contributes to IMI’s goal of raising patients’ awareness and participation in pharmaceutical R&D. This patient-led academy will provide scientifically reliable, objective, comprehensive information to patients on pharmaceutical R&D. It will increase the capacity of well-informed patients to be effective advocat ...
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 33

 TERMINÉ 

European Modular Education and Training Programme in Safety Sciences for Medicines (SAFESCIMET)

Date du début: 1 janv. 2010, Date de fin: 30 nov. 2016,

Background:In current drug safety education and training in Europe, an integrative and translational approach is lacking. This shortfall has been identified by EUFEPS. The IMI (‘Strategic Research Agenda’), the FDA and the EMEA have also characterised this fact as a crucial gap in the education and training of scientists evaluating the safety of drug candidates and new medicines. Scope and objecti ...
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 34

 TERMINÉ 

Chemical Manufacturing Methods for the 21st Century Pharmaceutical Industries (CHEM21)

Date du début: 1 oct. 2012, Date de fin: 30 sept. 2016,

CHEM21 is a project that will develop a broad based portfolio of sustainable technologies for green chemical intermediate manufacture aimed at the pharmaceutical industry. Initially working with the EFPIA members the collaborators of CHEM21 will analyse a number of projects that are in development to decide which the priorities are for technology development. This analysis will also be used to upd ...
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 19

 TERMINÉ 

Low cost flexible integrated composite process (LOWFLIP)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2016,

Fibre-reinforced polymer composite materials are leading candidates as component materials to improve the efficiency and sustainability of many transport modes. The advantages of high performance composites are numerous: they include lighter weight, the ability to tailor lay-ups for optimum strength and stiffness, improved fatigue life, corrosion resistance and, with good design practice, reduced ...
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 11

 TERMINÉ 

New Models for Preclinical Evaluation of Drug Efficacy in Common Solid Tumours (PREDECT)

Date du début: 1 févr. 2011, Date de fin: 30 avr. 2016,

Traditional preclinical discovery methods, particularly for target validation, poorly predict drug efficacy, causing a high attrition rate in costly late-stage clinical trials. The PREDECT consortium will focus on complex but transferable, next generation in vitro and in vivo models for breast, prostate and lung cancers. Models will be investigated for their improved potential to validate novel th ...
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 23

 TERMINÉ 

The Plant Cell Wall Training Consortium (WallTraC)

Date du début: 1 juin 2011, Date de fin: 29 févr. 2016,

"Plant cell walls constitute a highly complex and dynamic entity of extreme importance in plant growth and development. Growing cell walls can be considered as ""fibre composites"", where cellulose microfibrils are embedded in a matrix of complex glycans. It is becoming increasingly apparent (i) that cell wall glycans are diverse in structural terms, (ii) that these structures are developmentally ...
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 11

 TERMINÉ 

simulation based application Decision support in Real-time for Efficient Agile Manufacturing (DREAM)

Date du début: 1 oct. 2012, Date de fin: 30 sept. 2015,

The scale and complexity of the modern manufacturing systems make essential the integration of predictive simulation modelling and optimisation methodologies into routine decision making processes. To address this challenge, DREAM will offer a radically new and extensible approach to simulation application engineering, leveraging state-of-the art research on simulation and simulation based optimiz ...
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 9

 TERMINÉ 

Efficient Energy Integrated Solutions for Manufacturing Industries (EFENIS)

Date du début: 1 août 2012, Date de fin: 31 juil. 2015,

The overall objective of EFENIS is to facilitate and accelerate a move to low carbon manufacturing processes and site management by deployment and demonstration of innovative energy management systems and enabling efficiency technologies, which extend the scope of energy management outside the boundaries of a single plant to total site and then beyond the total site to district heating/cooling sys ...
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 18

 TERMINÉ 

Pharmaceutical Medicine Training Programme (PHARMATRAIN)

Date du début: 1 mai 2009, Date de fin: 30 avr. 2014,

"The proposed Pharmaceutical Medicine Training Programme provides a comprehensive solution for the complex needs of integrated drug development for all professionals involved, incl. physicians, pharmaceutical scientists,biologists, biometricians, health economists, and safety and regulatory scientists from universities, regulatory agencies, large, middle-sized and small pharmaceutical enterprises, ...
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 52

 TERMINÉ 

Multiscale Modeling of Chemical and Biochemical Systems (MULTIMOD)

Date du début: 15 déc. 2009, Date de fin: 14 déc. 2013,

"The MULTIMOD Training Network will have duration of 48 months and will bring together 8 academic research groups with 5 industrial partners from 8 European countries to undertake innovative research and scientific research training in “Multi-Scale Computational Modeling of Chemical and Biochemical Systems”. The network will provide unique cross- and multi-disciplinary training opportunities for 1 ...
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 13

 TERMINÉ 

Integrated synthesis and purification of single enantiomers (INTENANT)

Date du début: 1 juin 2008, Date de fin: 31 mai 2011,

Several industries have an increasing interest in improving their access to pure single enantiomers of biologically active substances. The latter often form the basis for valued added products relevant for, among others, the pharmaceutical, cosmetic, and food industries. Up to now there exist two generally rivalling concepts for producing pure enantiomers. One approach is based on developing and a ...
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 11