4 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Elucidation of MicroRNAs as Regulators of Metabolism and Targets for Therapeutic Intervention (METABOLOMIRS)
Date du début: 1 juil. 2010, Date de fin: 30 juin 2015,
Small RNA-mediated regulation of gene expression is a recent addition to fundamental gene regulatory mechanisms that directly or indirectly affect possibly every gene of a eukaryotic genome. The predominant sources of small RNA in somatic tissues are microRNA genes that encode short dsRNA hairpins of evolutionary conserved sequence. Disorders of metabolism, such as obesity and type 2 diabetes are ...
Voir le projet
1
Participant partenaire
TERMINÉ
Functional analysis of transcription factors in L-cell biology (TRAFALOGY)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2014,
"L-cells in the intestinal epithelium are specialized enteroendocrine cells which secrete several peptide hormones after a meal, including glucagon-like peptide 1 (GLP1), oxyntomodulin (OXM) and peptide tyrosine tyrosine (PYY). These hormones are key regulators of glucose metabolism and body weight, by stimulating insulin release by pancreatic beta cells, slowing down gastric emptying and by actin ...
Voir le projet
1
Participant partenaire
TERMINÉ
Collaborative European effort to Develop Diabetes Diagnostics (CEED3)
Date du début: 1 déc. 2008, Date de fin: 30 nov. 2012,
"CEED3 (Collaborative European Effort to Develop Diabetes Diagnostics) has as its central objective, the development of diagnostic tools to differentiate specific subgroups of diabetic patients to allow individualisation of patient care. CEED3 will achieve this by integrating basic science findings from animal models, cell studies, and large scale genetic studies with clinical observations and tes ...
Voir le projet
12
Participants partenaires
TERMINÉ
HighNoon: adaptation to changing water resources availability in northern India with Himalayan glacier retreat and changing monsoon pattern (HighNoon)
Date du début: 1 mai 2009, Date de fin: 30 avr. 2012,
The hydrological system of Northern India is based on two main phenomena, the monsoon precipitation in summer and the growth and melt of the snow and ice cover in the Himalaya, also called the “Water Tower of Asia”. However, climate change is expected to change these phenomena and it will have a profound impact on snow cover, glaciers and its related hydrology, water resources and the agricultural ...
Voir le projet