7 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Molecular Reclassification to Find Clinically Useful Biomarkers for Systemic Autoimmune Diseases (PRECISESADS)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,
We concur to the IMI on “Reclassification of SLE, connective tissue diseases and RA” call by presenting a proposal aimed at using the power of OMICs, and bioinformatics to identify new classifications for diseases known to share common pathophysiological mechanisms. Such knowledge has not been applied to individual patients, depriving them from potential benefits in terms of the use of new therape ...
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30
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TERMINÉ
A Novel Non-Invasive Prenatal Diagnosis for Genetic Disorders (NIPD)
Date du début: 1 mai 2013, Date de fin: 30 avr. 2018,
Non-Invasive Prenatal Diagnosis (NIPD) has been one of the most fascinating research fields during the last decade. The identification of small amounts of fetal DNA in maternal circulation has opened new possibilities for NIPD. Up until today, two methods have achieved accurate and validated NIPD methods for trisomy 21. The first NIPD for trisomy 21 was based on next generation sequencing and the ...
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2
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TERMINÉ
A New GEnetic LABoratory for non-invasive prenatal diagnosis (ANGELab)
Date du début: 1 oct. 2012, Date de fin: 31 mars 2017,
This project will develop a family of In-Vitro Diagnostic Systems that will transfer for the first time novel Non Invasive Prenatal Diagnostic (NIPD) methods in tube to a LabonaChip format. This family will consist of three research systems chosen to cover all prenatal diagnosis models:- ANGELAB1. This system will use a LabonaChip to extract fetal DNA from the mother´s plasma based on differences ...
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16
Participants partenaires
TERMINÉ
THALAssaemia MOdular Stratification System for personalized therapy of beta-thalassemia (THALAMOSS)
Date du début: 1 nov. 2012, Date de fin: 31 oct. 2016,
THALAMOSS is aimed at development of universal sets of markers and techniques for stratification of β-thalassaemia patients into treatment subgroups for (a) onset and frequency of blood transfusions, (b) choice of iron chelation, (c) induction of fetal hemoglobin, (d) prospective efficacy of gene-therapy. At present, no framework exists to guide therapeutic decisions and personalised treatment of ...
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14
Participants partenaires
TERMINÉ
A NEXT-GENERATION, SECURE LINKED DATA MEDICAL INFORMATION SPACE FOR SEMANTICALLY-INTERCONNECTING ELECTRONIC HEALTH RECORDS AND CLINICAL TRIALS SYSTEMS ADVANCING PATIENTS SAFETY IN CLINICAL RESEARCH (Linked2Safety)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2014,
The vision of the proposed Linked2Safety project is to advance clinical practice and accelerate medical research, to improve the quality of healthcare, benefiting public health, and to enhance patients' safety; by providing pharmaceutical companies, healthcare professionals and patients with an innovative semantic interoperability framework, a sustainable business model, and a scalable technical i ...
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13
Participants partenaires
TERMINÉ
"Improving Diagnoses of Mental Retardation in Children in Central Eastern Europe and Central Asia through Genetic Characterisation and Bioinformatics/-Statistics," (CHERISH)
Date du début: 1 févr. 2009, Date de fin: 31 juil. 2012,
"Mental retardation (MR) is a highly heterogeneous disorder and is of genetic origin in about 50% of the cases. Despite recent progress in research the causes and the pathophysiology of MR remains obscure. It is essential to investigate this in order to develop future diagnostic and therapeutic strategies. The overall goal of this proposal is to establish an interdisciplinary Eastern Europe and Ce ...
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11
Participants partenaires
TERMINÉ
Point-Of-Care MONitoring and DIagnostics for Autoimmune Diseases (POCEMON)
Date du début: 1 janv. 2008, Date de fin: 31 août 2011,
The POCEMON project aims to the hardware and software development of a multi-purpose autoimmune diseases diagnostic platform by combining Lab-on-Chip (LOC) technologies, genomic microarrays of HLA (human leukocyte antigens) typing, microelectronics, mobile devices, intelligent algorithms and wireless communications. The multi-purpose platform will be provided as a portable integrated platform with ...
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