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Normalisation of immune reactivity in old age – from basic mechanisms to clinical application (TOLERAGE)
Date du début: 1 avr. 2008, Date de fin: 30 sept. 2012,
"When restoration of the immune response in older age is the target of basic and clinical research, boosting innate and adaptive immunity, e.g. by more efficient vaccination strategies, is the general approach. However, TOLERAGE has a fundamentally different focus, i.e. restoring the age-dependent decline of auto-tolerance that underlies the development of the paradigmatic age-associated diseases ...
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