3 projets européens trouvés
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TERMINÉ
Understanding and fighting metastasis by modulating the tumour microenvironment through interference with the protease network (MICROENVIMET)
Date du début: 1 mars 2008, Date de fin: 29 févr. 2012,
"The MICROENVIMET project proposes innovative approaches for building a comprehensive understanding of the interplay between cancer cells and their microenvironment both at primary and secondary sites. The objectives are to identify molecular pathways involved in the regulation of metastatic dissemination to lung, liver, lymph node and bone. To achieve these objectives, the original experimental a ...
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9
Participants partenaires
TERMINÉ
Identification and functional characterization of genetic cancer risk variants (CancerGene)
Date du début: 1 mars 2008, Date de fin: 29 févr. 2012,
This Industry-Academia Partnership and Pathways (IAPP) joins three groups which have hitherto focused on different aspects of cancer genetics. deCODE genetics (deCODE) has recently identified several genetic risk variants that are associated with increased risk of cancer, including two distinct genetic prostate cancer risk variants on chromosome 8q24. The University of Torino (UNITO) group has id ...
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3
Participants partenaires
TERMINÉ
HGF/SF and MET in metastasis (SFMET)
Date du début: 1 avr. 2008, Date de fin: 30 sept. 2011,
"The growth and motility factor HGF/SF and its receptor MET define a paracrine signalling system which controls the migration of several cell lineages in embryogenesis and tissue repair. In a large number of human tumours, cancer cells hijack HGF/SF and MET signalling in order to invade adjacent tissue and initiate metastasis. The evidence for this is strong, broad and consistent and highlights ...
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