Plus de 40 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Clinical proof of concept through a randomised phase II study: a combination of immunotherapy and stereotactic ablative radiotherapy as a curative treatment for limited metastatic lung cancer (IMMUNOSABR)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2022,
IMMUNOSABR is geared towards opening up a new paradigm in treating metastatic cancer by obtaining clinical proof of concept for a novel bi-modal curative treatment strategy. High precision stereotactic ablative radiotherapy (SABR) is combined with immunotherapy to form a powerful synergistic anti-tumour strategy. The approach relies on the direct cytotoxic effect of SABR, the abscopal effect of ra ...
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17
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TERMINÉ
Paraplegia Prevention in Aortic Aneurysm Repair by Thoracoabdominal Staging with ‘Minimally-Invasive Segmental Artery Coil-Embolization’: A Randomized Controlled Multicentre Trial (PAPA-ARTIS)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,
Chronic aortic aneurysms are permanent and localized dilations of the aorta that remain asymptomatic for long periods of time but continue to increase in diameter before they eventually rupture. Left untreated, the patients’ prognosis is dismal, since the internal bleeding of the rupture brings about sudden death. Although successful treatment cures the disease, the risky procedures can result in ...
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26
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TERMINÉ
Mobility trajectories of young lives: Life chances of transnational youths in Global South and North (MO-TRAYL)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,
The objective of MO-TRAYL is to develop a better understanding of the relationship between migration and young people’s life-chances by studying youth’s mobility trajectories. How the life chances of youths, defined as their educational performance, psychological well-being and transitions into adulthood, are impacted by migration are of relevance for European cities that are faced with a growing ...
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1
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TERMINÉ
An Integrated European ‘Flagship’ Program Driving Mechanism-based Toxicity Testing and Risk Assessment for the 21st Century (EU-ToxRisk)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2021,
The vision of EU-ToxRisk is to drive a paradigm shift in toxicology towards an animal-free, mechanism-based integrated approach to chemical safety assessment. The project will unite all relevant disciplines and stakeholders to establish: i) pragmatic, solid read-across procedures incorporating mechanistic and toxicokinetic knowledge; and ii) ab initio hazard and risk assessment strategies of chemi ...
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43
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TERMINÉ
Tackling the Achilles Heel of Immunotherapy: Validating imaging biomarkers and targeting the immunological niche of tumour hypoxia (HYPOXIMMUNO)
Date du début: 1 déc. 2016, Date de fin: 30 nov. 2021,
Lung cancer is the most common cause of death from cancer worldwide with 1.59 million deaths annually and it places the highest economic burden of all cancers on the EU at €18.8billion. These figures call for a major transformation of the therapeutic management of lung cancer. The recent developments in immunotherapy give new hope. At present a significant minority of patients benefit from immune ...
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1
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TERMINÉ
EuroPubHealth Plus
Date du début: 1 sept. 2016, Date de fin: 31 août 2021,
... health functions or disciplines: • Health Promotion (University of Granada/Andalusian School of Public Health, taught in Spanish), Spain;• Leadership in European Public Health (University of Maastricht, English), The Netherlands;• Governance of Health Systems in transition (Jagiellonian University Medical College of Krakow, English), Poland;• Environmental and Occupational Health Sciences (EHESP ...
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6
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TERMINÉ
Migrant Life Course and Legal Status Transition (MiLifeStatus)
Date du début: 1 août 2016, Date de fin: 31 juil. 2021,
When does citizenship provide a boost to migrant integration? A fast-track to citizenship can maximise the potential for settlement success, though too short a pathway can disincentivise integration. Not all migrants have an equal interest in naturalising and some are discouraged by restrictive policies. Yet little is known about why, how and for whom legal status transition matters and, especiall ...
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1
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TERMINÉ
European Intellectual Property Institutes Network - Innovation Society (EIPIN IS)
Date du début: 1 mars 2017, Date de fin: 28 févr. 2021,
EIPIN IS is a comprehensive project at the forefront of multidisciplinary research, examining the role of intellectual property (IP) as a complex adaptive system in innovation. The focus will be on the European regulatory framework for fostering innovation with the aim of enhancing Europe’s capacity for innovation-based sustainable economic growth. The longstanding European Intellectual Property I ...
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5
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TERMINÉ
The birth of the digital doctor? A comparative anthropology of medical techno-perception (DigitalDoctors)
Date du début: 1 mars 2016, Date de fin: 28 févr. 2021,
Digital technologies are reconfiguring medical practices in ways we still don’t understand. This research project seeks to examine the impact of the digital in medicine by studying the role of pedagogical technologies in how doctors learn the skills of their profession. It focuses on the centuries-old skill of physical examination; a sensing of the body, through the body. Increasingly medical stud ...
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1
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TERMINÉ
Molecule-to-man pain network (PAIN-Net)
Date du début: 1 févr. 2017, Date de fin: 31 janv. 2021,
Neuropathic pain affects 5% of the general population and 40% of patients with neurological diseases, and has a key role in the pathophysiology of cancer pain that affects up to 50% of patients in the early disease stage and 30% of survivors, causing an enormous social burden. Treatments are inadequate with less than 50% of patients achieving 50% of pain relief at best, while up to 30% of cancer p ...
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13
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TERMINÉ
Small vessel diseases in a mechanistic perspective: Targets for InterventionAffected pathways and mechanistic exploitation for prevention of stroke and dementia (SVDs-at-target)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,
Stroke and dementia rank among the most pressing health issues in Europe. Cerebral small vessel diseases (SVDs) have emerged as a central link between these two major co-morbidities. SVDs account for more than 30% of strokes and at least 40% of dementia cases. They encounter multiple distinct diseases that can be separated based on their underlying genetic defects, risk factors, and clinical prese ...
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14
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TERMINÉ
Empowering Patients by Professional Stress Avoidance and Recovery Services (STARS)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
Patient EmpowermentIndividualized tackling of unnecessary stress, in particular when related to healthcare procedures, promises to enhance the autonomy and quality of life of many people and yield a significant contribution to self-empowerment, thus relieving careers and related persons from personal assistance. Not at least, also a considerable economic relief (see Impact).This is the topic the S ...
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13
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TERMINÉ
Building complex life through self-organization: from organ to organism (ORCHESTRATE)
Date du début: 1 oct. 2016, Date de fin: 30 sept. 2020,
A major challenge in regenerative medicine is to create phenotypic functioning tissues by controlling cell behaviour. We particularly lack the ability to form complex tissues composed of multiple cell types and with three-dimensional architecture, which are defining features of most tissues. We know that cells are conferred with the ability to choreograph their own development through self-organiz ...
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1
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TERMINÉ
Imaging Brain Circuits to Decode Brain Computations: Multimodal Multiscale Imaging of Cortical Microcircuits to Model Predictive Coding in Human Vision (MULTICONNECT)
Date du début: 1 juin 2015, Date de fin: 31 mai 2020,
The human brain is one of the largest and most complex biological networks known to exist. The architecture of its circuits, and therefore the computational basis of human cognition, remains largely unknown. The central aim of this proposal is to image human cortical connectivity at multiple spatial scales in order to understand human cortical computations. Whereas canonical cortical microcircuits ...
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1
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TERMINÉ
3D Scaffolds as a Stem Cell Delivery System for Musculoskeletal Regenerative Medicine (CELL HYBRIDGE)
Date du début: 1 mai 2015, Date de fin: 30 avr. 2020,
Aging worldwide population demands new solutions to permanently restore damaged tissues, thus reducing healthcare costs. Regenerative medicine offers alternative therapies for tissue repair. Although first clinical trials revealed excellent initial response after implantation of these engineered tissues, long-term follow-ups demonstrated that degeneration and lack of integration with the surroundi ...
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1
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TERMINÉ
European Vascular Interventions and Therapeutic Innovation Network (EVOluTION)
Date du début: 1 avr. 2016, Date de fin: 31 mars 2020,
EVOluTION, a pioneering network within EU in view of its focus on endogenous protective mechanisms, is formed to provide training for 11 young researchers in innovative therapeutic strategies, integrating early detection and prevention, to yield novel approaches to the management of chronic vascular and metabolic diseases that affect the increasing ageing population of Western societies. Fully ali ...
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6
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TERMINÉ
MOtivating end-users Behavioral change by combined ICT based tools and modular Information services on energy use, indoor environment, health and lifestyle (MOBISTYLE)
Date du début: 1 oct. 2016, Date de fin: 31 mars 2020,
The overall aim of MOBISTYLE is to raise consumer awareness and awareness of ownership, thus empowering consumers and providing confidence of choosing the right thing, by providing attractive tailor-made combined knowledge services on energy use, indoor environment, health and lifestyle, by ICT-based solutions. This awareness will support and motivate end-users to well informed pro-active behavi ...
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10
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TERMINÉ
Interdisciplinary Network for Dementia Utilising Current Technology (INDUCT) (INDUCT)
Date du début: 1 mars 2016, Date de fin: 29 févr. 2020,
Dementia raises complex challenges for people with dementia, their families, and society. The European Parliament has called for investment in high quality, innovative technology research to improve dementia care but so far there has been little benefit because research has generally been limited, small scale and methodologically flawed. In particular: the poor understanding between research and b ...
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9
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TERMINÉ
Engineering in vitro microenvironments for translation of cell-based therapies for tendon repair (Tendon Therapy Train)
Date du début: 1 févr. 2016, Date de fin: 31 janv. 2020,
Tendon Therapy Train is a research, training and innovation programme for human and equine tendon repair and regeneration that will exploit recent advancements in tissue engineering by self-assembly (TESA) technologies which have led to the clinical translation and commercialisation of advanced therapy medicinal products (ATMPs). Although TESA therapies have the potential to revolutionise healthc ...
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9
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TERMINÉ
Translating neuroimaging findings from research into clinical practice (PSYSCAN)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2020,
Abstract 9Neuroimaging (NI) has enormous potential to improve the clinical care of patients with psychiatric disorders, but has yet to deliver. The PSYSCAN project will address this issue directly by developing a NI-based tool that will help clinicians resolve key clinical issues in the management of patients with psychotic disorders. Clinicians will use the tool to assess patients with a standard ...
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24
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TERMINÉ
Role of European Mobility and its Impacts in Narratives, Debates and EU Reforms (REMINDER)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2019,
The overarching goal of the project is to understand the economic, social, institutional and policy factors that have shaped the impacts of free movement and public debates about it. It aims to help European policymakers develop policy responses that inspire public trust, ensure the fairness and sustainability of free movement, and maintain inclusive policies that reduce inequalities across the co ...
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14
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TERMINÉ
Image-Guided Surgery (IGS) and Personalised Postoperative Immunotherapy To Improving Cancer Outcome (ISPIC)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,
The basic concept of our proposal is to develop nanoparticle-based encapsulated libraries of different immunotherapeutic biomolecules for treatment after surgery as part of a novel cancer management strategy. The current state-of-art for the management of cancer starts with surgery, after identification of an accessible tumour mass. Surgery remains an effective treatment option for many types of c ...
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14
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TERMINÉ
Conflict, Competition, Cooperation and Complexity: Using Evolutionary Game Theory to model realistic populations (FourCmodelling)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,
"Real animals and human populations are complex, involving structural relationships depending upon space and time and varied interactions between potentially many individuals. Human societies feature family units, communities, companies and nations. Some animal also have complex societies, such as primate groups and social insect colonies. Single organisms themselves can be thought of as complex e ...
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5
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TERMINÉ
Energy for Smart Objects (EnSO)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,
The goal of EnSO is to develop and consolidate a unique European ecosystem in the field of autonomous micro energy sources (AMES) supporting Electronic European industry to develop innovative products, in particular in IoT markets. In summary, EnSO multi-KET objectives are:• Objective 1: demonstrate the competitiveness of EnSO energy solutions of the targeted Smart Society, Smart Health, and Smart ...
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36
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TERMINÉ
OpenRiskNet: Open e-Infrastructure to Support Data Sharing, Knowledge Integration and in silico Analysis and Modelling in Risk Assessment (OpenRiskNet)
Date du début: 1 déc. 2016, Date de fin: 30 nov. 2019,
Toxicology and risk assessment are undergoing a paradigm shift, from a phenomenological to a mechanistic discipline based on in vitro and in silico approaches that represent an important alternative to classical animal testing applied to the evaluation of chronic and systemic toxicity risks. Large databases and highly sophisticated methods, algorithms and tools are available for different tasks su ...
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14
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TERMINÉ
European Network for Research, Good Practice and Innovation for Sustainable Energy (ENERGISE)
Date du début: 1 déc. 2016, Date de fin: 30 nov. 2019,
Considerable challenges remain today regarding Europe´s transition towards a decarbonised energy system that meets the economic and social needs of its citizens. Rebound effects, that is, a full or partial cancelling-out of efficiency gains over time through increased overall energy use, highlight the centrality of consumption in multi-scalar decarbonisation efforts, urgently requiring attention f ...
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10
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TERMINÉ
Functionally graded Additive Manufacturing scaffolds by hybrid manufacturing (FAST)
Date du début: 1 déc. 2015, Date de fin: 30 nov. 2019,
Additive Manufacturing (AM) market has grown with trends higher than 20% every year in the last 10 years. Their fast uptake is due to different innovative factors such as no shape limits in manufacturing process, full customisation on the single artefact, localised production and no waste material. In particular the ability to print any shape allows to design the products not following the constri ...
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9
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TERMINÉ
ELEVATING THE INTERNATIONALISATION OF HIGHER EDUCATION IN MOLDOVA
Date du début: 15 oct. 2016, Date de fin: 14 oct. 2019,
The ELEVATE project addresses the process of internationalisation of Moldovan higher education as the one that requires immediate national and institutional response and joint action. Enabling national HE bodies and HEIs to strategically manage comprehensive internationalisation in the provision of education, research, mobility and services are regarded to be the project’s overall objective and th ...
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13
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TERMINÉ
Homo'poly
Date du début: 1 sept. 2016, Date de fin: 31 août 2019,
Homo'poly seeks to promote understanding and acceptance of diversity, especially homosexuality.Because sustained gender specific inequalities in education and upbringing have been exposed in numerous studies, national and international organizations are looking for approaches to complement their co-educational infrastructure for the specific needs of both genders, to fight discrimination and to pr ...
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14
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TERMINÉ
Chinese Heritage Tours and Adoptive Origin Stories: Towards a Transnational Adoptive Field (OriginStories)
Date du début: 1 sept. 2016, Date de fin: 31 août 2019,
China became the largest source of adopted children worldwide since its Transnational Adoption Program in 1992.As adoptees are coming of age, some are interested in exploring their roots. Concurrently, as international adoptions come under the scrutiny of critical groups in sending and receiving countries, heritage tours have become a popular way to satisfy the needs of different actors involved: ...
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1
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TERMINÉ
EU Training Network on Novel Targets and Methods in Atrial Fibrillation (AFib-TrainNet)
Date du début: 1 sept. 2015, Date de fin: 31 août 2019,
The AFib-TrainNet consortium will enable promising young scientists to become excellent research leaders of the future, capable of fighting the challenges that Atrial Fibrillation (AF) presents to the European population. AF is the most common sustained cardiac arrhythmia, occurring in between 1-2% of the general population. More than 6 million Europeans suffer from this arrhythmia and its prevale ...
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7
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TERMINÉ
European Network of Research Ethics and Research Integrity (ENERI) (ENERI)
Date du début: 1 sept. 2016, Date de fin: 31 août 2019,
The “European Network of Research Ethics and Research Integrity” (ENERI) establishes an operable platform of actors in the fields of research ethics and research integrity.The reliability and credibility of research and science do not depend only on its excellence and productivity but also on the players’ awareness of highest standards of ethics in research and commitment to a responsible conduct ...
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11
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TERMINÉ
Sarcopenia and Physical fRailty IN older people: multi-componenT Treatment strategies (SPRINTT)
Date du début: 1 juil. 2014, Date de fin: 30 juin 2019,
The current healthcare systems are built around the traditional paradigm of patients suffering from a single acute illness. They are therefore largely unprepared to face the increasing demands for health services arising from the expansion of an older population with specific medical needs related to multiple chronic disorders. As a consequence, the medical conditions of a large and growing seg ...
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27
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TERMINÉ
Biobased self-functionalised self-reinforced composite materials based on high performance nanofibrillar PLA fibres (BIO4SELF)
Date du début: 1 mars 2016, Date de fin: 30 juin 2019,
BIO4SELF aims at fully biobased self-reinforced polymer composites (SRPC). To produce the SRPCs two polylactic acid (PLA) grades are required: a low melting temperature (Tm) one to form the matrix and an ultra high stiffness and high Tm one to form the reinforcing fibres. To reach unprecedented stiffness in the reinforcing PLA fibres, we will combine PLA with bio-LCP (liquid crystalline polymer) f ...
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16
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TERMINÉ
THALEA II - Telemonitoring and Telemedicine for Hospitals Assisted by ICT for Life saving co-morbid patients in Europe As part of a Patient personalised care program of the EU (THALEA II)
Date du début: 1 juin 2016, Date de fin: 31 mai 2019,
Public procurement of innovative solutions (PPI) shortens the route to market, sets free the potential of early adopters to implement an innovation and enables public procurers to efficiently answer market demands of innovative products.THALEA II is the first follow-up PPI in healthcare for Intensive Care Units (ICU). It will bring an innovative product to the European healthcare market aiming to ...
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6
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TERMINÉ
New Approaches in the Conservation of Contemporary Art (NACCA)
Date du début: 1 juin 2015, Date de fin: 31 mai 2019,
The importance of European cultural heritage has been generally acknowledged. A significant part of this heritage, however, modern and contemporary art, runs a great risk of getting lost for future generations, because it is particularly difficult to preserve. Proper care requires resolving fundamental questions concerning the identity and authenticity of modern and contemporary artworks and the c ...
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10
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TERMINÉ
Disabling Radiotherapy resistance in Cancer Treatment (DIRECT)
Date du début: 1 mai 2014, Date de fin: 30 avr. 2019,
"Cancer is a devastating disease affecting 1 in 3 people in their lifetime. The incidence is rising because of our aging population and causes a huge economic impact on our society because of hospitalization and lost productivity. Radiotherapy alone or in combination with surgery and/or chemotherapy is used in ~50% of all patients and uses ionizing radiation to induce DNA breaks that are lethal to ...
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2
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TERMINÉ
Characterizing Atrial fibrillation by Translating its Causes into Health Modifiers in the Elderly (CATCH ME)
Date du début: 1 mai 2015, Date de fin: 30 avr. 2019,
Atrial fibrillation (AF) is the most common cardiac arrhythmia, with a prevalence of 1.5-2% in European populations. By being a major cause of stroke, dementia, heart failure, and premature death, AF is a major threat to healthy ageing. Despite increasing knowledge on the diverse mechanisms that cause the AF substrate in individual patients, current strategies for prevention and therapy of AF rema ...
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9
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TERMINÉ
Big Data and models for personalized Head and Neck Cancer Decision support (BD2Decide)
Date du début: 1 janv. 2016, Date de fin: 30 avr. 2019,
"Cancers of the Head and Neck Region (HNC) are the 6th more deadly cancers worldwide: in Europe ~150.000 new cases are detected and ~70.000 patients die every year. The main reasons for high mortality are the fact that the majority of cases are diagnosed in advanced Stage and the intrinsic heterogeneity of such tumors. At present the only adopted treatment decision method is based on TNM (Tumor-ly ...
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13
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TERMINÉ
Expanding the industrial use of Robust Oxidative Biocatalysts for the conversion and production of alcohols (ROBOX) (ROBOX)
Date du début: 1 avr. 2015, Date de fin: 31 mars 2019,
Oxygen functionalities are key functional groups in many of today’s chemicals and materials. The efficient introduction of oxygen-functionalities into raw materials are key chemical transformations in bulk and fine chemicals. Innovative bio-catalytic oxidation routes using molecular oxygen (from air) under benign and mild (pH) conditions such as ambient temperature and pressure can greatly improve ...
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