4 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Exploring the combined role of genetic and non-genetic factors for developing Age-Related Macular Degeneration: A systems level analysis of disease subgroups, risk factors, and pathways (EYE-RISK)
Date du début: 1 mai 2015, Date de fin: 30 avr. 2019,
Age-related macular degeneration (AMD) is the world’s most important age-related blinding disorder. The current proposal utilises epidemiological data describing clinical phenotype, molecular genetics, lifestyle, nutrition, and in-depth retinal imaging derived from existing longitudinal European epidemiological cohorts and biobanks to provide three major insights needed for long-lasting prevention ...
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13
Participants partenaires
TERMINÉ
European Consortium for the Study of a Topical Treatment of iCRVO to prevent Neovascular Glaucoma (STRONG)
Date du début: 1 oct. 2012, Date de fin: 31 mars 2018,
Neovascular glaucoma (NVG) is a very aggressive and rare type of glaucoma: yet, it contributes disproportionately to blindness from all eye diseases. NVG is also the second most common cause for the removal of the eye-ball across all eye diseases, usually because of intractable pain. The major cause of NVG is Ischaemic Central Retinal Vein Occlusion (CRVO) leading to neovascularisation, obstructio ...
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9
Participants partenaires
TERMINÉ
Orphan Drug for Acanthamoeba Keratitis (ODAK)
Date du début: 1 déc. 2012, Date de fin: 30 nov. 2017,
This project will undertake preclinical and clinical research of the Orphan Drug Polihexanide (PHMB). The main objective is to provide a safe and effective drug for the treatment of the rare ocular disease Acanthamoeba keratitis (AK) tested according to international regulatory standards. This debilitating infectious disease is caused by a free living protozoan which, in the absence of treatment ...
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6
Participants partenaires
TERMINÉ
European Consortium for the Early Treatment of Diabetic Retinopathy (EUROCONDOR)
Date du début: 1 mars 2012, Date de fin: 30 juin 2016,
Diabetic retinopathy (DR), the leading cause of blindness among working-age individuals in developed countries has been classically considered to be a microcirculatory disease of the retina. However, there is growing evidence to suggest that retinal neurodegeneration is an early event in the pathogenesis of DR. For this reason, it is reasonable to hypothesize that therapeutic strategies based on n ...
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