7 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Multiple manifestations of genetic and non-genetic factors in Multiple Sclerosis disentangled with a multi-omics approach to accelerate personalised medicine (MultipleMS)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,
The complex interactions between genetic and non-genetic factors produce heterogeneities in patients as reflected in the diversity of pathophysiology, clinical manifestations, response to therapies, disease development and progression. Yet, the full potential of personalized medicine entails biomarker-guided delivery of efficient therapies in stratified patient populations.MultipleMS will therefor ...
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25
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TERMINÉ
Directed Protein Evolution for Synthetic Biology and Biocatalysis (ES-Cat)
Date du début: 1 mars 2017, Date de fin: 28 févr. 2021,
ES-Cat will use directed evolution as a tool to reproduce Nature's remarkable ability to generate molecular machines - in particular enzymes – that perform at levels near perfection. Instead of seeing rational and combinatorial approaches as alternatives, we combine them in this network to achieve a ‘smarter’ and more efficient exploration of protein sequence space. By harnessing the forces of Dar ...
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11
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TERMINÉ
Molecular Tools for Nucleic Acid Manipulation for Biological Intervention (MMBio)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
MMbio will bridge the classically separate disciplines of Chemistry and Biology by assembling leading experts from academia and non-academic partners (industry, technology transfer & science communication) to bring about systems designed to interfere therapeutically with gene expression in living cells. Expertise in nucleic acid synthesis, its molecular recognition and chemical reactivity is combi ...
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13
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TERMINÉ
Protein-excipient Interactions and Protein-Protein Interactions in formulation (PIPPI)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,
The revolution of biotechnology has led to the creation of various types of therapeutic biologics with the potential to provide treatment for new chronic and malignant diseases. Though the potential advantages of biologics lay in their high specificity and potency combined with few side effects, their formulation still remains a large challenge to pharmaceutical scientists. This is in part due to ...
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8
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TERMINÉ
Cancer Associated Fibroblasts (CAF) Function in Tumor Expansion and Invasion (CAFFEIN)
Date du début: 1 oct. 2012, Date de fin: 30 sept. 2016,
...equired for pharmaceutical industry, and knowledge in setting up biomedical start-up companies. To this end, the network comprises two full industrial partners: the established pharmaceutical company Medimmune, a global leader in immunopharmaceuticals, and the small biotech company Gimmune, which used breakthrough results in nanotechnology to establish a new enterprise.The research focus of CAFFEI ...
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11
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TERMINÉ
Stromal Cell- Immune Cell Interactions in Health and Disease (STROMA)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,
STROMA is an Initial Training Network promoting the study of stromal cell – immune system interactions during stroma development and function in health and disease. In STROMA we have bought together world leading experts from academia and industry in Europe to address the key scientific questions in this emerging field. STROMA will promote the training of three Experienced Researchers (ER) and s ...
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12
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TERMINÉ
European Network on Directed Evolution of Functional Proteins (ENEFP)
Date du début: 15 oct. 2008, Date de fin: 14 oct. 2012,
"This project intends to use directed evolution as tool to reproduce Nature's remarkable ability to generate molecular machines - in particular enzymes – that perform at levels near perfection. By harnessing the forces of Darwinian evolution in the laboratory we want to (i) screen large and diverse genome libraries for protein with new and useful functions, (ii) optimize existing proteins for appl ...
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