2 projets européens trouvés
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TERMINÉ
Multiple manifestations of genetic and non-genetic factors in Multiple Sclerosis disentangled with a multi-omics approach to accelerate personalised medicine (MultipleMS)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,
The complex interactions between genetic and non-genetic factors produce heterogeneities in patients as reflected in the diversity of pathophysiology, clinical manifestations, response to therapies, disease development and progression. Yet, the full potential of personalized medicine entails biomarker-guided delivery of efficient therapies in stratified patient populations.MultipleMS will therefor ...
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TERMINÉ
Adipokines as Drug Targets to Combat Adverse Effects of Excess Adipose Tissue (ADAPT)
Date du début: 1 févr. 2008, Date de fin: 31 janv. 2012,
"Obesity represents the major risk factor for the cardiometabolic syndrome, which is an epidemic disease that generates a severe global socio-economic burden for the public health systems. Enhanced production of proinflammatory adipocytokines by expanded adipose tissue is now considered as a key event in the pathogenesis of this syndrome. This process involves i) the systemic release of adipokines ...
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