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Effects of atrial fibrillation on the distribution and frequency of spontaneous calcium release events in human atrial myocytes (AF in Human Myocytes)
Date du début: 2 avr. 2013, Date de fin: 1 avr. 2015,
Atrial fibrillation (AF) is the most common cardiac arrhythmia and currently there are no efficient treatments. The host laboratory has linked AF to abnormal Ca2+ handling by increased spontaneous sarcoplasmic reticulum (SR) Ca2+ release in human atrial myocytes (HAMs), and that an underlying mechanism is an increased expression and activation of A2A receptors. We hypothesize that the spatial dist ...
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