9 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Exploitation of Glycosylation Signatures for Precision Medicine (GlySign)
Date du début: 1 oct. 2016, Date de fin: 30 sept. 2020,
GlySign is a research training network for the translation of glycomic clinical biomarkers for Precision Medicine (PM). Complex, distinctive changes occur in the glycomics profiles or - Glycan Signatures - of human glycoproteins during progression of many chronic diseases including cancer and inflammatory conditions. The three beneficiaries of the GlySign Consortium have been instrumental in contr ...
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3
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TERMINÉ
Exploiting Glycosylation of Colorectal Cancer for the development of improved diagnostics and therapeutics (GlyCoCan)
Date du début: 1 sept. 2015, Date de fin: 31 août 2019,
Colorectal cancer (CRC) is a major worldwide cancer burden with about 1.4 million cases in 2012 and an annual mortality of approximately 700,000. Early detection is crucial as treatment is most efficient in early stages where population based screenings could substantially reduce incidence and mortality.Current screening techniques are invasive or lack sensitivity and specificity. Moreover, the mo ...
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9
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TERMINÉ
Parasite glycobiology and anti-parasitic strategies (GLYCOPAR)
Date du début: 1 déc. 2013, Date de fin: 30 nov. 2017,
"Protozoan parasites and helminths are the cause of some of the most devastating diseases worldwide and a major effort is needed to be able to control or eliminate these diseases. Glycoconjugates are abundant and ubiquitous on the surface of many parasites and they are frequently involved in their survival strategies by forming a protective barrier against host defences. A common feature of the pa ...
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13
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TERMINÉ
Methods for high-throughput (HTP) analysis of protein glycosylation (HighGlycan)
Date du début: 1 nov. 2011, Date de fin: 31 oct. 2016,
Glycosylation is a post-translational modification that enriches protein complexity and function. Dysregulation of glycosylation is associated with a wide range of diseases, including cancer, diabetes, as well as congenital, cardiovascular, immunological and infectious disorders. A number of studies identified potentially important glycan disease biomarkers. With regard to biotechnology, proper gl ...
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9
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TERMINÉ
Diagnostic and prognostic biomarkers for inflammatory bowel disease IBD-BIOM (IBD-BIOM)
Date du début: 1 oct. 2012, Date de fin: 30 sept. 2016,
Inflammatory bowel diseases affect 0.8% of the Europeans, and are associated with high morbidity, definite mortality and an increasing economic burden. Current diagnostic tools and therapeutics for IBD are unsatisfactory. Development of biomarkers allowing insights into pathogenesis, prognosis and targeted therapy is a major unmet need. This programme addresses that need. IBD-BIOM is a multidisci ...
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11
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TERMINÉ
Gaining sage on the Epoetins' saga: assessing long term risks and advancing towards better Epoetin driven treatment modalities (EPOCAN)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2014,
EpoCan aims to develop and implement a comprehensive interdisciplinary strategy to assess the long-term risks of erythropoietin (EPO) and its derivatives (epoetins) on tumour growth progression and thromboembolic events in cancer patients, cardiovascular events, and the development of cancer in chronic kidney disease. Approximately 400,000 patients across Europe receive epoetins treatment each yea ...
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13
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TERMINÉ
Development of a cost effective system for exchanging information and managing risks of chemicals for the construction industry, addressing new challenges related to European chemical legislation (ChemXchange)
Date du début: 1 janv. 2009, Date de fin: 31 oct. 2012,
This proposal addresses the great challenge faced by the SMEs in the construction sector of complying with today’s obligations and regulatory requirements regarding exchange of information on hazardous chemicals between various actors in the sector. The European construction sector, being the largest industrial sector highly dominated by small enterprises, is a major downstream user of chemicals a ...
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15
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TERMINÉ
Development of carbohydrate array technology to systematically explore the functional role of glycans in healthy and diseased states (EuroGlycoArrays)
Date du début: 1 sept. 2008, Date de fin: 31 août 2012,
The development and production of glycoarrays will provide the foreground knowledge necessary to lead to a step change in the diagnosis and treatment of diseases ranging from cancers to autoimmune diseases. Carbohydrates play a pivotal role in the molecular interactions that govern biological events at the centre of health and disease. This has become more evident as the characterisation and ident ...
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17
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TERMINÉ
RACE networkRFID: Raising Awareness and Competitiveness on RFID in Europe (RACE networkRFID)
Date du début: 1 mars 2009, Date de fin: 29 févr. 2012,
The RACE networkRFID initiative has been developed to raise awareness of Radio Frequency Identification across Europe through the establishment of a federating platform for all key European stakeholders in the development and use of RFID technology and applications.The European Union (EU), through the Commission, has made a substantial investment in research, standards and regulatory developments ...
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