9 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
From Omics to Patient: Improving Diagnostics of Pathogenic Yeasts (OPATHY)
Date du début: 1 sept. 2015, Date de fin: 31 août 2019,
OPATHY is an innovative translational research training network that will explore the potential of omics technologies, including genomics, transcriptomics and proteomics, to study the interactions of yeasts that cause disease to humans (e.g. Candida and Cryptococcus sp.) with their host, and to develop new diagnostic tools to monitor yeast infections in the clinic. Today, these infections are poor ...
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10
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TERMINÉ
Imaging Mass Spectrometry of Fungal – Bacterial Interplay (FUNBIT)
Date du début: 1 mars 2016, Date de fin: 28 févr. 2018,
FUNBIT aims to enhance the discovery rate of natural products applying a multidisciplinary workflow guided by Imaging MS.Microbial genetics predict that the natural products we have discovered so far are only the tip of the iceberg, thus we may be missing the antibiotics and biopesticides of the future. In fact, many natural compounds remain invisible under standard laboratory conditions, but thei ...
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1
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TERMINÉ
European Consortium for High-Throughput Research in Rare Kidney Diseases (EURENOMICS)
Date du début: 1 oct. 2012, Date de fin: 30 sept. 2017,
EURenOmics will integrate several established consortia devoted to rare kidney diseases with eminent need and potential for diagnostic and therapeutic progress (i.e. steroid resistant nephrotic syndrome, membranous nephropathy, tubulopathies, complement disorders such a haemolytic uraemic syndrome, and congenital kidney malformations). The Consortium has access to the largest clinical cohorts asse ...
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29
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TERMINÉ
Quantitative Biology for Fungal Secondary Metabolite Producers (QuantFung)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,
QuantFung represents the first European training platform for the production of novel bioactive compounds based on fungal synthetic biology. The ITN will train 11 early-stage (ESR) and 4 experienced researchers (ER) as new problem-solving, creative European scientists in interdisciplinary and intersectorial biotechnological research ranging from modelling, network analysis, systems biology (genomi ...
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9
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TERMINÉ
KRAB zinc finger gene biology in evolution and disease (KRAB-ZNF)
Date du début: 1 juil. 2011, Date de fin: 30 juin 2015,
The „KRAB-ZNF“ initiative is driven by recent observations that KRAB-ZNF genes, an evolutionarily conserved gene family of more than 350 transcriptional repressors encoded in the human genome, are predominantly expressed in testis and fetal brain. To elucidate functions of KRAB ZNF genes in evolution and diseases, experts in KRAB ZNF gene biology (B1/P1), proteomics (B1/P2), systems biology and ag ...
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4
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TERMINÉ
Signaling circuitry controlling fungal virulence: identification and characterization of conserved and specific fungal virulence genes as common antifungal targets (ARIADNE)
Date du début: 1 janv. 2010, Date de fin: 31 mai 2014,
"Fungi are heterotrophic microorganisms with devastating impact on agriculture and human health. Agricultural production worth billions of € is destroyed annually by fungal diseases. Human fungal infections have severe consequences on the growing number of immuno-compromised patients, with high mortality rates associated with Aspergillus and Candida infections. There is a critical need to further ...
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10
Participants partenaires
TERMINÉ
Identification of new molecules able to bypass the cell wall compensatory pathways in the pathogenic fungus Aspergillus fumigatus (CellWallPath)
Date du début: 1 mars 2010, Date de fin: 28 févr. 2013,
Aspergillus fumigatus is the most important air-borne fungal pathogen, causing severe infections with invasive growth in immunocompromised patients. For growth in all habitats, the fungus needs to be able to sense environmental stimuli and to transduce signals via specific signalling cascades. Calmodulin/calcineurin, Ras/cAMP, mTOR and general Mitogen-activated protein kinase (MAPK) signalling pat ...
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1
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TERMINÉ
Pathogenomics and Systems Biology of Fungal Infections – An Integrative Approach (FINSysB)
Date du début: 1 oct. 2008, Date de fin: 30 sept. 2012,
The vision of the FINSysB Network is to generate bright, ambitious and well-trained young researchers capable of contributing significantly to the knowledge-base and economy of the European Union. We will achieve this goal by providing a strong, multidisciplinary training for early stage and experienced researchers in the pathobiology, genomics, molecular biology, bioinformatics and systems biolo ...
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13
Participants partenaires
TERMINÉ
Unravelling the infectome of Candida albicans (CaInfectome)
Date du début: 1 juin 2008, Date de fin: 31 mai 2010,
The opportunistic human fungal pathogen, Candida albicans causes a wide range of serious disease manifestations, especially in individuals with an impaired immune system. The ability of C. albicans to successfully infect almost every anatomical niche of the human host is both a serious medical problem and an interesting biological property. It is known from in vitro transcriptional profiling that ...
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