2 projets européens trouvés
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TERMINÉ
Generation of a new class of antiretrovirals targeting HIV-cellular cofactors interactions (HIVINNOV)
Date du début: 1 oct. 2012, Date de fin: 30 sept. 2015,
Highly active antiretroviral therapy is effective at controlling HIV-1 replication, however emergence and transmission of drug-resistant viruses is increasing, including viruses resistant to the newly developped integrase catalytic inhibitors. It is essential that new antiretrovirals (ARVs) become available. Most ARVs in development belong to the classes of viral enzyme inhibitors. Since HIV requi ...
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TERMINÉ
Targeting assembly of infectious HIV particles (HIV ACE)
Date du début: 1 mars 2008, Date de fin: 31 août 2011,
"AIDS remains one of the major life threatening infectious diseases in the world today. A constant supply of novel antiretrovirals (ARVs) is needed to respond to the limitations of current drugs. By the end of 2007, the therapeutic arsenal against HIV is expected to comprise ARVs blocking all major steps of HIV replication, except for particle assembly and budding. Members of HIV-ACE were instrume ...
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