10 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Exploring Functional and Developmental Osteoclast Heterogeneity in Health and Disease (EUROCLAST)
Date du début: 1 sept. 2013, Date de fin: 31 août 2017,
Euroclast proposes a research training program on osteoclast biology in the context of osteoclast-driven diseases. Osteoclasts are the complex, multinuclear cells responsible for bone breakdown. Many diseases of osteoclast malfunctioning manifest in bone loss, for example, osteoporosis, cancer-induced bone disease, periodontitis, or rheumatoid arthritis, all conditions set to increase in an ageing ...
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11
Participants partenaires
TERMINÉ
B-cell development and gene regulation in three dimensions (genomic interactions)
Date du début: 1 août 2012, Date de fin: 31 juil. 2016,
A major challenge of modern cell biology is to understand how elaborate transcriptional programs drive developmental processes and maintain cellular identity. In mammals temporal and cell type specific gene regulation depend on regulatory elements in the genome. Genome-wide mapping studies have lead to the identification of myriads of regulatory elements. Strikingly these elements not only exist i ...
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1
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TERMINÉ
European programme in Pharmacovigilance and Pharmacoepidemiology (EU2P)
Date du début: 1 sept. 2009, Date de fin: 30 juin 2016,
The Eu2P training network in Pharmacovigilance and Pharmacoepidemiology will meet the needs of industry,regulatory authorities and academia at the European level. It will give access to a harmonised training programme that gathers complementary specialized and eminent European partners. The Eu2P consortium consists of course providers with aproven record including the University of Bordeaux (Eu2P ...
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24
Participants partenaires
TERMINÉ
Evaluation of antibiotics (ciprofloxacin and fluconazole) for the treatment of infections in preterm and term neonates (TINN)
Date du début: 1 nov. 2008, Date de fin: 31 oct. 2015,
The aim of TINN is to evaluate ciprofloxacin, fluconazole and micafungin in neonates; two anti-infectious drugs included in the EMEA priority list of the therapeutic areas that need specific drug evaluation in preterm and term neonates. These drugs are prescribed off-label to treat neonatal infections that are life threatening situations and associated with long-term complications. In order to val ...
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16
Participants partenaires
TERMINÉ
Switch recombination: a model system for DNA editing and repair in human lymphocytes with relevance for primary immunodeficiency and cancer formation (ImmunoSwitch)
Date du début: 1 déc. 2009, Date de fin: 30 nov. 2014,
The aim of this project is to try to understand the complex molecular mechanisms involved in DNA editing, repair and recombination during immunoglobulin class switch recombination (CSR) and somatic hypermutation (SHM). We have developed a series of PCR-based assays to study in vivo generated CSR junctions and the pattern of mutations introduced in the immunoglobulin variable region genes in human ...
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1
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TERMINÉ
Teaming-up for exploiting e-Infrastructures' potential to boost RTDI in Africa (eI4Africa)
Date du début: 1 nov. 2012, Date de fin: 31 oct. 2014,
The eI4Africa project aims to boost the research, technological development and innovation (RTDI) potential of African e-Infrastructures and to support policy dialogues and Euro-African cooperation in the framework of the Joint Africa-EU Strategic Partnership on 'trade, regional integration and infrastructures' (JAES Partnership #3) as well as the Joint Africa-EU Strategic Partnership on 'science, ...
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8
Participants partenaires
TERMINÉ
The effects of antibiotic administration on the emergence and persistence of antibiotic-resistant bacteria in humans and on the composition of the indigenous microbiotas at various body sites (antiresdev)
Date du début: 1 nov. 2009, Date de fin: 30 avr. 2013,
The objective of the HEALTH-2009-2.3.1-2 call is to study the impact of different antibiotics on the prevalence of resistant bacteria in the human host. In ANTIRESDEV we will achieve this objective using the approaches suggested in the call as follows. We will use culture-based and culture-independent approaches to investigate the impact of four different types of antibiotics (with different modes ...
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12
Participants partenaires
TERMINÉ
Production and delivery of antibody fragments against gastrointestinal pathogens by lactobacilli (LACTOBODY)
Date du début: 1 févr. 2008, Date de fin: 30 avr. 2012,
"Enteric infections remain a major cause of morbidity and mortality globally, accounting for an estimated 2 millions deaths each year. Effective preventive and therapeutic interventions are not yet available for many etiological agents of diarrheal diseases. Furthermore, even where vaccines are available, the lag time needed to induce an immune response can be critical in epidemic situations. We ...
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8
Participants partenaires
TERMINÉ
European Genetic Disease Diagnostics (EURO-GENE-SCAN)
Date du début: 1 janv. 2009, Date de fin: 31 déc. 2011,
"Molecular techniques have become more efficient, increasingly precise and much cheaper, resulting in an unprecedented discovery rate of inherited disease genes. In areas such as primary immunodeficiencies (PID), muscle disorders, growth deficiencies, hearing/vision impairments and metabolic diseases, very large numbers of different genes have been found to carry mutations in diseases with heterog ...
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5
Participants partenaires
TERMINÉ
The Pathophysiology and Natural Course of Patients with Primary Antibody Deficiencies (PAD) (EURO-PADnet)
Date du début: 1 mai 2008, Date de fin: 30 avr. 2011,
This medium-sized collaborative project will document and monitor the natural course and study the pathophysiology of Primary Antibody Deficiencies (PAD). PADs are rare inborn errors of the immune system with an estimated incidence of
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