14 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Combatting Bacterial Resistance in Europe - Carbapenem Resistance (COMBACTE-CARE)
Date du début: 1 mars 2015, Date de fin: 28 févr. 2020,
Multi-drug resistant Gram-negative bacteria (MDR-GNB): the ultimate challenge!Antibiotic resistance is a global public health concern recently elevated to the top three threats identified by the WHO, and subject of numerous national and international government activities. Although focused strategies have beneficially influenced infection rates due to methicillin resistant Staphylococcus aureus (M ...
Voir le projet
23
Participants partenaires
TERMINÉ
European Gram Negative Antibacterial Engine (ENABLE)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2020,
The intensive use and misuse of antibiotics has resulted in some level of antibiotic resistance in essentially all human bacterial pathogens. There is a growing concern that the loss of therapeutic options will present us with a post-antibiotic era where present and future medical advances are negated. Resistant bacteria dramatically reduce the possibilities of treating infections effectively, a ...
Voir le projet
42
Participants partenaires
TERMINÉ
European Prevention of Alzheimer’s Dementia Consortium (EPAD)
Date du début: 1 janv. 2015, Date de fin: 31 déc. 2019,
Background:The secondary prevention of Alzheimer’s dementia (AD) is achievable if we can identify individuals at risk of disease progression defined by biomarker evidence of AD pathology and no or only minimal clinical symptoms and engage them in a standing adaptive clinical trial, of the highest quality, testing multiple interventions. To achieve this, EPAD will also provide the analytical infras ...
Voir le projet
40
Participants partenaires
TERMINÉ
Platform foR European Preparedness Against (Re-)emerging Epidemics (PREPARE)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,
Far from receding, the threats posed by infections with epidemic potential grow ever greater. Although Europe has amongst the best healthcare systems in the world, and also the world’s supreme researchers in this field, we lack co-ordination and linkage between networks that is required to respond fast to new threats. This consortium of consortia will streamline our response, using primary and sec ...
Voir le projet
27
Participants partenaires
TERMINÉ
Development and application of global lipidomic arrays to inflammatory vascular disease (LIPIDArray)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,
How lipids are regulated on a global scale during vascular inflammation is not known. Thus, a major challenge exists to describe and catalog the total lipidome, in particular enabling the identification of new biologically active lipids, and description of changes. This is analogous to ‘omics’ of DNA, RNA and protein, but instead describing diversity of lipids in tissue samples. Importantly, thi ...
Voir le projet
2
Participants partenaires
TERMINÉ
Low-carbon Lifestyles and Behavioural Spillover (CASPI)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,
"Responding to climate change has profound implications for behaviour; yet policies to achieve this change have met with limited success. A key challenge for environmental social scientists is the need to move forward in understanding how to bring about change in consumption, community and political behaviours, which is commensurate to the scale of the climate change challenge. One promising area ...
Voir le projet
1
Participant partenaire
TERMINÉ
The Coevolution of Life and Arsenic in Precambrian Oceans (CLAPO)
Date du début: 1 sept. 2013, Date de fin: 31 août 2018,
The ubiquity of arsenic resistant genes across all of life’s variety suggests a close intimacy between arsenic biogeochemistry and evolution, over geological time scales. However, the behaviour of arsenic in past environments where life originated and its impact on our evolution is essentially unknown. Arsenic is of particular importance because of its toxic properties, prevalence in tight associa ...
Voir le projet
2
Participants partenaires
TERMINÉ
Investigation of Novel biomarkers and Definition of the role of the microbiome In Graves’ Orbitopathy (INDIGO) (INDIGO)
Date du début: 1 mai 2014, Date de fin: 30 avr. 2018,
"Graves' orbitopathy (GO), also known as thyroid eye disease, affects approximately 3 million people in Europe with an estimated socioeconomic burden of 6.4 billion euros per annum. GO is a complication of Graves' disease which is an autoimmune disease and the commonest cause of an overactive thyroid gland. The treatment of GO remains unsatisfactory and the majority of patients report long-term im ...
Voir le projet
5
Participants partenaires
TERMINÉ
Neurobiology and Treatment of Adolescent Female Conduct Disorder: The Central Role of Emotion Processing (FEMNAT-CD)
Date du début: 1 sept. 2013, Date de fin: 28 févr. 2018,
Conduct Disorder (CD) and Oppositional Defiant Disorder with symptoms of Conduct Disorder (which is included among the abbreviation “CD” throughout the proposal) has a highly negative impact for the affected individual as well as for families and society. Although the number of females exhibiting serious aggressive behaviours is growing, the majority of studies on aetiology and treatment of CD hav ...
Voir le projet
19
Participants partenaires
TERMINÉ
Managing Aquatic ecosystems and water Resources under multiple Stress (MARS)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,
"MARS will support managers and policy makers in the practical implementation of the WFD, of related legislation and of the Blueprint to Safeguard Europe’s Water Resources by conducting new research and synthesising existing knowledge concerning effects and management of multiple stressors in surface water and groundwater bodies; by advising the 3rd RMBP cycle and the revision of the WFD; and by d ...
Voir le projet
25
Participants partenaires
TERMINÉ
Taking imaging into the therapeutic domain: Self-regulation of brain systems for mental disorders (BRAINTRAIN)
Date du début: 1 nov. 2013, Date de fin: 31 oct. 2017,
Our proposal is based on the idea that real-time functional neuroimaging can be used to train patients to regulate their own brain activity via neurofeedback training and thus modulate the brain networks of mental disorder, restore function, improve symptoms and promote resilience. We have brought together the core groups that have been instrumental in the development of methods for real-time func ...
Voir le projet
12
Participants partenaires
TERMINÉ
Female Investigators in Nonlinear Optical Nanoscopy - FINON (FINON)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,
The aim of this ITN is to take the category of Nonlinear Optical Microscopy (NOM) techniques into the nano-dimension, allowing for label-free three-dimensional (3D), dynamic imaging of macromolecular arrangements and nanostructures by probing inherent higher-order electronic and molecular vibrations with novel detection concepts. Specific S&T objectives are to (A) explore the use of nano-sized sca ...
Voir le projet
6
Participants partenaires
TERMINÉ
Human pluripotent stem cell differentiation, safety and preparation for therapeutic transplantation in Huntington’s disease (Repair-HD)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,
This project will tackle the huge complexity of taking stem cell therapies to clinical application for neurodegenerative disease by focusing on selective differentiation of a single neuronal phenotype (medium spiny striatal neuron: MSN) for a single well-defined disease (Huntington’s: HD). Our consortium contains expertise in all elements required to drive this technology to the point of clinical ...
Voir le projet
10
Participants partenaires
TERMINÉ
Retrofitable Automated Microtome System incorporating contactless sample transportation for Histology process (MICROLEAN)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2016,
Histology is the microscopic examination of cell tissue samples and is routinely performed in research labs and, more widely, in hospitals for the early detection of diseases (histopathology). Histology is a complex process requiring several steps for the tissue sample preparation. The most demanding and time-consuming step is the microtomy, where the tissue sample, now dehydrated and placed insid ...
Voir le projet