23 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
European Medical Information Framework (EMIF)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,
In response to the need to tackle increasingly complex medical research questions, a growing amount of human health data is being collected, either in routine Electronic Healthcare Record (EHR) databases, through research-driven cohort studies, in biobanks or related efforts. However, data sources are typically fragmented and contain information gaps which prevent their full exploitation. EMIF aim ...
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64
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TERMINÉ
Preserving old antibiotics for the future : assessment of clinical efficacy by a pharmacokinetic/pharmacodynamic approach to optimize effectiveness and reduce resistance for off-patent antibiotics (AIDA)
Date du début: 1 déc. 2011, Date de fin: 30 nov. 2017,
The AIDA project aims to answer the question of clinical effectiveness and optimal dosing of 5 off-patent antibiotics for infections caused by multiple drug resistant (MDR) bacteria in three randomized controlled clinical trials. In an era of increasing emergence of drug resistance (EDR) and lack of new antibiotics, old off- patent antibiotics are increasingly being prescribed to patients. However ...
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19
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TERMINÉ
European Consortium for High-Throughput Research in Rare Kidney Diseases (EURENOMICS)
Date du début: 1 oct. 2012, Date de fin: 30 sept. 2017,
EURenOmics will integrate several established consortia devoted to rare kidney diseases with eminent need and potential for diagnostic and therapeutic progress (i.e. steroid resistant nephrotic syndrome, membranous nephropathy, tubulopathies, complement disorders such a haemolytic uraemic syndrome, and congenital kidney malformations). The Consortium has access to the largest clinical cohorts asse ...
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29
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TERMINÉ
VitaminD3-Omega3-Home Exercise- HeALTHy Ageing and Longevity Trial (DO-HEALTH)
Date du début: 1 janv. 2012, Date de fin: 30 juin 2017,
As the European population is ageing rapidly, the growing number of seniors with age-related chronic diseases poses a challenge on European societies and health care systems. Therapeutic interventions that are effective, affordable and well-tolerated in the prevention of chronic disease are urgently needed and will have an outstanding impact on public health as a whole. Among the most promising in ...
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25
Participants partenaires
TERMINÉ
EpiHealthNet
Date du début: 1 mai 2013, Date de fin: 30 avr. 2017,
Scientific evidence clearly indicates that ageing and health in adult life is programmed by genetic and epigenetic mechanisms early in life.Developmental plasticity in response to the environment, including nutrient availability, of mammalian embryos indicates the capacity fornewly emerging embryonic and extraembryonic cell lineages to initiate compensatory responses which may attune nutrient deli ...
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9
Participants partenaires
TERMINÉ
Health Care Reform: the iMpact on practice, oUtcomes and costs of New roles for health pROfeSsionals (MUNROS)
Date du début: 1 oct. 2012, Date de fin: 31 mars 2017,
The proposed research responds to the call for research into the ‘Quality, Efficiency and Solidarity of Health Systems’. European countries are reforming their health systems to improve health care delivery. One of the ways they are doing this is by changing skill mix within teams delivering health services: extending the roles of existing health professions and introducing new ones. This project ...
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9
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TERMINÉ
Transforming Magnetic Resonance Spectroscopy into a Clinical Tool (TRANSACT)
Date du début: 1 mars 2013, Date de fin: 28 févr. 2017,
"In vivo Magnetic Resonance Spectroscopy and Spectroscopic Imaging (MRS(I)) are unique, indispensable techniques for non-invasive metabolic imaging. Important areas where MRS(I) can make a difference are oncology and neurology, where metabolic changes due to, e.g., tumour formation, can be detected earlier and more sensitively than with morphological imaging modalities alone. Despite its huge prov ...
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10
Participants partenaires
TERMINÉ
European Patients' Academy on Therapeutic Innovation (EUPATI)
Date du début: 1 févr. 2012, Date de fin: 31 janv. 2017,
"The proposed project ""European Patients' Academy on Therapeutic Innovation"" (EUPATI) contributes to IMI’s goal of raising patients’ awareness and participation in pharmaceutical R&D. This patient-led academy will provide scientifically reliable, objective, comprehensive information to patients on pharmaceutical R&D. It will increase the capacity of well-informed patients to be effective advocat ...
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33
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TERMINÉ
Towards Early diagnosis and biomarker validation in Arthritis Management (EURO-TEAM)
Date du début: 1 nov. 2012, Date de fin: 31 oct. 2016,
An ideal intervention in a chronic inflammatory disease such as Rheumatoid Arthritis (RA) would be a preventive one. In order to develop preventive strategies and therapies two key developments need to occur: (1) Biomarkers need to be identified that can be used to predict an individual’s risk of developing RA. (2) Modifiable disease mechanisms need to be identified and characterized in the early ...
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17
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TERMINÉ
International study for treatment of childhood relapsed ALL 2010 with standard therapy, systematic integration of new agents, and establishment of standardized diagnostic and research (INTREALL)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2016,
Though survival of children with acute lymphoblastic leukaemia (ALL) has improved, relapse remains a leading cause of mortality in childhood cancer. Given the rarity of the disease, only a large international cooperative group can recruit sufficient patients for prospective studies with specific questions in biologic subgroups. Under the umbrella of the I-BFM SG all relevant mainly European study ...
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29
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TERMINÉ
The Evolutionary Origins of Agriculture (EOA)
Date du début: 1 mai 2011, Date de fin: 31 janv. 2016,
The transition from a mobile hunter-gatherer lifestyle to one of settled agriculture is arguably the most fundamental change in human development since the origin of the human species, and the major question is why hunter-gatherer populations abandoned this way of life in favour of an agricultural existence. A crucial element in this change is the evolution of the crops upon which agriculture is f ...
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2
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TERMINÉ
"Self-care Support for People with Long Term Conditions, Diabetes and Heart Disease: A Whole System Approach" (EU-WISE)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,
"The overall aim of this project is to offer a deeper understanding of the different mechanisms involved in the management of chronic conditions with a specific focus on how initiatives are translated and embedded into the illness management practices in peoples’ everyday life. It is in work, domestic and community settings where these practices are shaped by the emotional, symbolic, ethical, eco ...
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10
Participants partenaires
TERMINÉ
Adapting Breast Cancer Screening Strategy Using Personalised Risk Estimation (ASSURE)
Date du début: 1 déc. 2012, Date de fin: 30 nov. 2015,
"While early detection of breast cancer by screening appears effective, many women derive little or no benefit from screening, due to the way it is currently organized: as a one-size-fits all approach irrespective of personalised risk factors. It is known, however, that some women are at a much higher risk of getting the disease than others, and that mammography is unsuitable for cancer detection ...
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10
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TERMINÉ
Rapid development and distribution of statistical tools for high-throughput sequencing data (RADIANT)
Date du début: 1 déc. 2012, Date de fin: 30 nov. 2015,
"High-throughput sequencing (HTS) is a powerful and rapidly evolving family of technologies with a multitude of applications. They include genetics of rare and common diseases, understanding of disease mechanism and progression through transcriptome and epigenome profiling, cancer stratification, personalised medicine and molecular systems biology of gene regulation. The genome, epigenome, transcr ...
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10
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TERMINÉ
Linking perturbed maternal environment during periconceptional development, due to diabetes, obesity or assisted reproductive technologies, and altered health during ageing (EpiHealth)
Date du début: 1 nov. 2011, Date de fin: 31 oct. 2015,
Scientific evidence clearly indicates that ageing and health in adult life is programmed by genetic and epigenetic mechanisms early in life. Developmental plasticity in response to the environment, including nutrient availability, of mammalian embryos indicates the capacity for newly emerging embryonic and extraembryonic cell lineages to initiate compensatory responses which may attune nutrient de ...
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7
Participants partenaires
TERMINÉ
Bottom-up reconstitution of a biomimetic bioartificial liver (RE-LIVER)
Date du début: 1 juil. 2012, Date de fin: 30 juin 2015,
The liver, by way of its central role in both endogenous and exogenous metabolism, is one of the most well-studied organs in the human body.Hepatic tissue and its derivatives have a wide range of in-vivo and in-vitro applications from whole organ or partial lobe transplant, bioartificial ex-vivo devices, treatment of metabolic disorders to toxicology, drug metabolism and tissue regeneration. On th ...
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5
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TERMINÉ
Semantic Interoperability for Health Network (SemanticHealthNet)
Date du début: 1 déc. 2011, Date de fin: 31 mai 2015,
SemanticHealthNet will develop a scalable and sustainable pan-European organisational and governance process for the semantic interoperability of clinical and biomedical knowledge, to help ensure that EHR systems are optimised for patient care, public health and clinical research across healthcare systems and institutions.Through a clinically-driven workplan, exemplified in cardiovascular medicine ...
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18
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TERMINÉ
FAll Repository for the design of Smart and sElf-adaptive Environments prolonging INdependent livinG (FARSEEING)
Date du début: 1 janv. 2012, Date de fin: 31 mars 2015,
Description
FARSEEING wants to provide an information basis for research and therapy development for fall prediction, prevention and support, by building the world’s largest fall repository. This database will facilitate the collection, analysis and processing of behavioural and physiological data related to falls, daily activity and physiol ...
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12
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TERMINÉ
Epidemiological Studies of Exposed Southern Urals Populations (SOLO)
Date du début: 1 mars 2010, Date de fin: 28 févr. 2015,
This project aims to improve estimates of the risks of long-term health effects associated with protracted external and internal radiation exposures, through further studies of exposed populations in the Southern Urals (Russian Federation). Specific objectives of the project are as follows: 1. To develop improved modules for estimating external doses to exposed cohorts in the Southern Urals. It is ...
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13
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TERMINÉ
"Low cost technologies and traditional ingredients for the production of affordable, nutritionally correct foods improving health in population groups at risk of poverty" (CHANCE)
Date du début: 1 févr. 2011, Date de fin: 31 juil. 2014,
"According to 2007 Eurostat statistics, there is a robust need to better understanding the nutritional existing barriers to healthy nutrition of 79 million EU-27 citizens at-risk-of-poverty. These European subclusters and ethnic populations have in common low purchasing power, limited education and the highest risk of diet-related diseases due to sub-optimal nutrition. CHANCE project will i) defin ...
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19
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TERMINÉ
Swarm Intelligence Simulations as Tools for Molecular Design of Better Medicines (SwarmDesignTools)
Date du début: 5 mars 2012, Date de fin: 4 mars 2014,
A new generation of medicines, diagnostics and materials are needed to fuel new advances in healthcare and technology. Critical to this are predictive quality software tools to guide molecular design. In the School of Pharmacy at the University of Manchester, our constant aim is to improve the accuracy of the software tools we use in drug design. The aim of this proposal is to develop a more effic ...
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1
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TERMINÉ
Linking genotype to phenotype for the rheumatoid arthritis susceptibility locus 6q23: beyond genome wide association studies (GENTOPHEN)
Date du début: 1 mars 2011, Date de fin: 28 févr. 2014,
"Rheumatoid arthritis (RA) is a chronic, disabling, complex autoimmune disease with a strong genetic component. After the well known HLA-DRB1 and PTPN22 genetic loci, the next most strongly associated locus is an intergenic region on 6q23, 180 Kb from the candidate gene TNFAIP3. The causal variants and their functional effects have not been identified yet. The aim of this project is to identify al ...
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1
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TERMINÉ
eHealth Innovation - Scaling up eHealth facilitated personalised health services: Developing a European roadmap for sustained eHealth Innovation (eHealth Innovation)
Date du début: 1 mai 2011, Date de fin: 31 oct. 2013,
eHealth Innovation TN will develop consensus among stakeholders and recommendations to-wards making innovative integrated, and therefore interoperable eHealth services operational and deployed at large scale in Europe.The focus will be to analyse, achieve consensus on and deliver a detailed summary report on how to achieve in the medium-term more patient/person-centred health services for an agein ...
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