4 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Novel Approaches to Bacterial Target Identification, Validation and Inhibition (NABATIVI)
Date du début: 1 févr. 2009, Date de fin: 31 juil. 2013,
Despite the advent of the antibiotic era, infectious diseases retain their pre-eminent position as major worldwide causes of morbidity and mortality. This problem has been worsen by the emergence of multi-antibiotic resistant bacteria and the failure of Pharmaceutical company drug discovery programmes to design antibiotics with truly novel modes of action. NABATIVI has put together a unique consor ...
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10
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TERMINÉ
NOTCH SIGNALING IN DEVELOPMENT AND PATHOLOGY (NotchIT)
Date du début: 1 janv. 2009, Date de fin: 31 déc. 2012,
Eight partners from six different EU countries will converge in NotchIT, a multi-site ITN aimed to increase the knowledge of cellular and molecular mechanisms by which Notch signaling regulates the development and pathology of different tissues. Notch signaling plays a key role in cell-fate determination and differentiation of various cell types and aberrant Notch signaling is associated with path ...
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11
Participants partenaires
TERMINÉ
Molecular mechanisms of neuronal restoration: novel approaches for Parkinson's Disease (MOLPARK)
Date du début: 1 avr. 2009, Date de fin: 30 sept. 2012,
"MOLPARK aims to define the basic cellular and molecular mechanisms underlying the generation, differentiation, survival and connectivity of nigrostriatal dopaminergic neurons and translate this knowledge into radically new therapeutic strategies for Parkinson's disease (PD). MOLPARK brings together two industrial partners and 6 world-renowned academic groups with a uniquely advantageous knowledge ...
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7
Participants partenaires
TERMINÉ
Understanding and fighting metastasis via dissection of the Core Invasive Machinery (MetaFight)
Date du début: 1 janv. 2008, Date de fin: 31 déc. 2010,
The co-operative Metafight project will perform functional studies to understand the dissemination and outgrowth of metastasis through systematic analysis of the Core Invasive Machinery contained within integrin-mediated ECM attachment structure. It includes a large and discretely localised intracellular signalling network which drives migration and invasion. Our strategy is based on the hypothesi ...
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