4 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Treatment of reperfusion injury using a mitochondrial targeted approach: towards a better understanding of the disease (MITOCARE)
Date du début: 1 janv. 2011, Date de fin: 31 déc. 2013,
"Current interventional treatment of acute myocardial infarction (AMI) focused on re-establishing cardiac reperfusion has significantly improved clinical outcome by reducing infarct size and mortality due to cardiac ischemia.It is now recognized that events triggered at reperfusion also result in cell death and may account for as much as 50% of the infarct volume, this being termed ischemia-reperf ...
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18
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TERMINÉ
European Project on Mendelian Forms of Parkinson’s Disease (MEFOPA)
Date du début: 1 avr. 2010, Date de fin: 30 sept. 2013,
"The Collaborative Project on Mendelian Forms of Parkinson’s Disease (MEFOPA) will bring together the major groups in Europe with a track-record in basic and clinical research on rare Mendelian forms of Parkinson’s disease (PD) in order to identify and validate relevant disease-related molecular pathways, drug-targets and biomarkers for disease susceptibility and progression.. Over the last years ...
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27
Participants partenaires
TERMINÉ
Therapeutic challenge in Leukodystrophies: Translational and ethical research towards clinical trials (LEUKOTREAT)
Date du début: 1 mars 2010, Date de fin: 31 août 2013,
Leukodystrophies (LDs) are inherited rare neurodegenerative diseases of the white matter and its main component, the myelin, that are affecting predominantly children. Severity of the disease is related to the axonal dysfunction due to myelin deficiency or destruction. Despite the achievement of remarkable advances made in the past decade, there is no current curative therapy. The development of t ...
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25
Participants partenaires
TERMINÉ
Mitochondrial dysfunction in neurodegenerative diseases: towards new therapeutics (Mitotarget)
Date du début: 1 févr. 2009, Date de fin: 31 mars 2012,
Mitochondrial dysfunction is a major hallmark of various neurodegenerative disorders including Alzheimer’s disease, Parkinson’s disease, Huntington’s diseases or Amyotrophic Lateral Sclerosis (ALS). However linking mitochondrial dysfunction to the pathogenesis of some of these diseases still needs to be elucidated. Furthermore, in pathologies where this link is already established, the question re ...
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