6 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Model-based preclinical development of anti-tuberculosis drug combinations (PREDICT-TB)
Date du début: 1 mai 2012, Date de fin: 30 oct. 2017,
Drug development in TB requires new integrated methods to transition the novel combination regimens needed to shorten first-line therapy and combat multi-drug resistance. Although new agents are emerging, the path to registration of such regimens remains uncertain while capacity for pivotal trials is limited. Selection and optimization of drug combinations for development depends on preclinical sy ...
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23
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TERMINÉ
CONFLICT LANDSCAPES & LIFE CYCLES: EXPLORING & PREDICTING AFRICAN POLITICAL VIOLENCE (GEOPV)
Date du début: 1 mai 2012, Date de fin: 30 avr. 2017,
"The central aim of this work is to explain what causes the various types of political violence found within and across African states. In contrast to the widespread view that conflict is confined to a few crisis prone states, new evidence suggests that almost all states are sites of substantial, widespread political insecurity (Raleigh et al. 2010). Civil war accounts for 35% of the conflict acro ...
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2
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TERMINÉ
Network of Excellence in Internet Science (EINS)
Date du début: 1 déc. 2011, Date de fin: 31 mai 2015,
The goal of EINS is coordinating and integrating European research aimed at achieving a deeper multidisciplinary understanding of the development of the Internet as a societal and technological artefact, whose evolution is increasingly interwined with that of human societies. Its main objective is to allow an open and productive dialogue between all the disciplines which study Internet systems und ...
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48
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TERMINÉ
Synaptic mechanisms underlying neural coding in the retina during visual response (Synapse Transmission)
Date du début: 1 mars 2013, Date de fin: 28 févr. 2015,
A formidable challenge for the visual system is to encode the statistical variability in the visual environment. For example, the vital statistics of contrast and luminance vary by several orders of magnitude within an image and during global changes in overall viewing conditions. The range of visual signals far exceeds the dynamic range of neurons in the retina.Traditional views dictate that duri ...
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2
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TERMINÉ
Mechanisms to Attack Steering Effectors of Rheumatoid Syndromes with Innovated Therapy Choices (Masterswitch)
Date du début: 1 déc. 2008, Date de fin: 30 nov. 2013,
Objective: To delineate the biological and molecular pathways that initiate and drive chronic inflammatory disease and to transform the knowledge obtained into the development of novel anti-inflammatory interventions. Focus will be given to Rheumatoid Arthritis (RA) since longitudinal data indicate that intensive treatment can prevent persistency and chronicity. State of the Art and beyond: The ...
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20
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TERMINÉ
MOLECULAR MECHANISMS OF APPETITIVE ASSOCIATIVE MEMORY (AMPA phosphorylation)
Date du début: 1 oct. 2007, Date de fin: 30 sept. 2011,
AMPA receptors mediate the majority of fast excitatory neurotransmission in the vertebrate nervous system and recent evidence has implicated AMPA receptor regulation in long-term potentiation (LTP) and long-term depression (LTD), cellular models of learning and memory. However, experimental evidence connecting synaptic plasticity and learning and memory remains scarce. Such evidence comes from dem ...
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