6 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Disabling Radiotherapy resistance in Cancer Treatment (DIRECT)
Date du début: 1 mai 2014, Date de fin: 30 avr. 2019,
"Cancer is a devastating disease affecting 1 in 3 people in their lifetime. The incidence is rising because of our aging population and causes a huge economic impact on our society because of hospitalization and lost productivity. Radiotherapy alone or in combination with surgery and/or chemotherapy is used in ~50% of all patients and uses ionizing radiation to induce DNA breaks that are lethal to ...
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2
Participants partenaires
TERMINÉ
BBMRI - Large Prospective Cohorts (BBMRI-LPC)
Date du début: 1 févr. 2013, Date de fin: 31 janv. 2017,
In recent years, biomedical research has crossed international borders in large, collaborative studies showing the value of multidisciplinarity and scale advantage. This has yielded valuable insights and some led to new and better medicines and treatments for diseases. However, disease-focused studies provide less insight in the real disease onset, the relative disease burden in the population, an ...
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36
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TERMINÉ
Platform for sharing best practices for management of rare diseases (RARE-BESTPRACTICES)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,
RARE-Bestpractices will develop a sustainable networking platform, supporting the collection of standardized and validated data and efficient exchange of knowledge and reliable information on rare diseases (RD).RD are characterized by low prevalence (EU – 5:10000 persons). There are more than 5000, overall affecting about 30 million citizens of all ages in the EU. RD are often life-threatening and ...
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16
Participants partenaires
TERMINÉ
Spatio-Temporal Modeling for Enhanced Automated Detection and Classification of Non-Mass Lesions in Breast MRI (MAMMA)
Date du début: 1 avr. 2014, Date de fin: 31 mars 2016,
The emphasis of this project lies in the development and evaluation of an intelligent and robust computer-assisted system for detecting and diagnosing breast lesions that present a non-mass-like enhancement and thus lead to a substantial improvement of the quality of breast MRI postprocessing, reduce the number of missed or misinterpreted cases leading to false-negative diagnosis, and avoid unnece ...
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1
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TERMINÉ
Capitalising Notch Biomarkers in the Drug Development Market (CAPNOTCH)
Date du début: 1 sept. 2013, Date de fin: 31 août 2014,
"CapNotch is the translation from discovery of multimodal cancer biomarkers of the Notch pathway to a strong market proposition. Biomarker products for validating specificity, efficacy and toxicity of preclinical compounds that target this pathway are highly wanted by academia and industry and could fuel progress in this area. One step further lays the opportunity to exploit such biomarkers for pa ...
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1
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TERMINÉ
Targeting the Notch Protease Interface (NOTCH PROTEOLYSIS)
Date du début: 1 sept. 2008, Date de fin: 28 févr. 2014,
NOTCH signaling is a highly conserved short-range signaling pathway involved in virtually every aspect of embryonic development and controls homeostatic self-renewal in many adult tissues. Germ line mutations in the NOTCH pathway cause several hereditary diseases, and somatic mutations are found in cancer. NOTCH pathway activity is governed by ligand induced proteolytic cleavage of the receptor in ...
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