3 projets européens trouvés
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TERMINÉ
BeTheCuRE (BTCURE)
Date du début: 1 avr. 2011, Date de fin: 31 mars 2017,
BTCure is based on the recognition that RA is a heterogeneous disease where a major subset involves adaptive immunity, and that animal models have to develop the line with the different subsets of the human diseases in order to be optimally used for drug discovery and drug evaluation. Our aim is to develop an understanding of the early process in human arthritis subsets and the animal models that ...
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41
Participants partenaires
TERMINÉ
Towards Early diagnosis and biomarker validation in Arthritis Management (EURO-TEAM)
Date du début: 1 nov. 2012, Date de fin: 31 oct. 2016,
An ideal intervention in a chronic inflammatory disease such as Rheumatoid Arthritis (RA) would be a preventive one. In order to develop preventive strategies and therapies two key developments need to occur: (1) Biomarkers need to be identified that can be used to predict an individual’s risk of developing RA. (2) Modifiable disease mechanisms need to be identified and characterized in the early ...
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17
Participants partenaires
TERMINÉ
Mechanisms to Attack Steering Effectors of Rheumatoid Syndromes with Innovated Therapy Choices (Masterswitch)
Date du début: 1 déc. 2008, Date de fin: 30 nov. 2013,
Objective: To delineate the biological and molecular pathways that initiate and drive chronic inflammatory disease and to transform the knowledge obtained into the development of novel anti-inflammatory interventions. Focus will be given to Rheumatoid Arthritis (RA) since longitudinal data indicate that intensive treatment can prevent persistency and chronicity. State of the Art and beyond: The ...
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