5 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
BeTheCuRE (BTCURE)
Date du début: 1 avr. 2011, Date de fin: 31 mars 2017,
BTCure is based on the recognition that RA is a heterogeneous disease where a major subset involves adaptive immunity, and that animal models have to develop the line with the different subsets of the human diseases in order to be optimally used for drug discovery and drug evaluation. Our aim is to develop an understanding of the early process in human arthritis subsets and the animal models that ...
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41
Participants partenaires
TERMINÉ
Vitamin D And LIfestyle Intervention for Gestational Diabetes Mellitus (GDM) Prevention (DALI)
Date du début: 1 mars 2010, Date de fin: 31 déc. 2015,
Europe is facing a rapidly growing threat from Type 2 diabetes mellitus (T2D), which is undoubtedly associated with an unhealthy diet and a more sedentary lifestyle. Evidence is accumulating that gestational diabetes mellitus (GDM) may be playing a role in this process. Thus it provides a significant opportunity for preventing future T2D. Not only is GDM prevalence on the rise, but intrauterine ex ...
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18
Participants partenaires
TERMINÉ
Mechanisms to Attack Steering Effectors of Rheumatoid Syndromes with Innovated Therapy Choices (Masterswitch)
Date du début: 1 déc. 2008, Date de fin: 30 nov. 2013,
Objective: To delineate the biological and molecular pathways that initiate and drive chronic inflammatory disease and to transform the knowledge obtained into the development of novel anti-inflammatory interventions. Focus will be given to Rheumatoid Arthritis (RA) since longitudinal data indicate that intensive treatment can prevent persistency and chronicity. State of the Art and beyond: The ...
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20
Participants partenaires
TERMINÉ
Fatty liver: Inhibition of Progression (FLIP)
Date du début: 1 janv. 2010, Date de fin: 30 juin 2013,
"Non-alcoholic fatty liver disease (NAFLD) has become one of the top concerns for the practising hepatogastroenterologist due to the obesity epidemic and its potential to progress to advanced liver disease which significantly impacts on overall and liver-related mortality. The aim of the FLIP (Fatty Liver: Inhibition of Progression) project is to understand and prevent the progression of liver dis ...
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17
Participants partenaires
TERMINÉ
Targeting OBesity-driven Inflammation (TOBI)
Date du début: 1 janv. 2008, Date de fin: 30 juin 2011,
"The TOBI project aims to analyse mechanisms provoking adipokine-mediated crosstalk and an inflammatory drift in obese patients. It will be the remit of this project to develop novel strategies to reduce or reverse major adipokine-mediated adverse interactions in peripheral tissues and by periorganic adipose tissue, namely insulin resistance and vascular dysfunction, respectively. Special attentio ...
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