12 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Neuropathic pain: biomarkers and druggable targets within the endogenous analgesia system (NEUROPAIN)
Date du début: 1 janv. 2014, Date de fin: 31 déc. 2018,
Neuropathic pain has a high incidence in Europe and often affects the patient’s emotional balance and quality of life. Recent meta-analyses have shown that conventional analgesic drugs are not sufficiently effective in these patients and are limited by serious side effects. The search for new analgesics is extremely difficult despite identification of several new potential targets and enormous inv ...
Voir le projet
12
Participants partenaires
TERMINÉ
Aggression subtyping for improved insight and treatment innovation in psychiatric disorders (AGGRESSOTYPE)
Date du début: 1 nov. 2013, Date de fin: 31 oct. 2018,
Aggression is a basic physiological trait with important roles throughout evolution, both in defence and predation. When expressed in humans in the wrong context, aggression leads to maladjustment, social impairment and crime. Despite this, knowledge about aggression aetiology is limited and current treatment strategies are insufficient. Contingent to a subdivision into impulsive and instrumental ...
Voir le projet
27
Participants partenaires
TERMINÉ
Integrated European –omics research project for diagnosis and therapy in rare neuromuscular and neurodegenerative diseases (Neuromics)
Date du début: 1 oct. 2012, Date de fin: 30 sept. 2017,
Neurodegenerative (ND) and neuromuscular (NM) disease is one of the most frequent classes of rare diseases, affecting life and mobility of 500,000 patients in Europe and millions of their caregivers, family members and employers. This NEUROMICS project brings together the leading research groups in Europe, five highly innovative SMEs and relevant oversea experts using the most sophisticated Omics ...
Voir le projet
20
Participants partenaires
TERMINÉ
IMAging GEnetics for MENtal Disorders (IMAGEMEND)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,
"Mental disorders are leading causes of disability, absence from work and premature retirement in Europe. While magnetic resonance imaging (MRI) facilities are broadly available and a vast research literature exists, few neuroimaging applications have reached clinical practice in psychiatry. A major problem is that mental illnesses are currently diagnosed as discrete entities defined clinically. I ...
Voir le projet
15
Participants partenaires
TERMINÉ
BBMRI - Large Prospective Cohorts (BBMRI-LPC)
Date du début: 1 févr. 2013, Date de fin: 31 janv. 2017,
In recent years, biomedical research has crossed international borders in large, collaborative studies showing the value of multidisciplinarity and scale advantage. This has yielded valuable insights and some led to new and better medicines and treatments for diseases. However, disease-focused studies provide less insight in the real disease onset, the relative disease burden in the population, an ...
Voir le projet
36
Participants partenaires
TERMINÉ
Biomarkers For Enhanced Vaccine Safety (BIOVACSAFE)
Date du début: 1 mars 2012, Date de fin: 31 déc. 2016,
BioVacSafe is a concise consortium of selected academic, public, and SME participants used to co-working in industry-led projects, organised into focused Activity Cores to generate knowledge and tools to benchmark licensed vaccine reactogenicity, and create practical and generalizable guidelines and techniques to enhance immunosafety of novel vaccines from pre-development to post-marketing surveil ...
Voir le projet
24
Participants partenaires
TERMINÉ
Genetic studies of pre-eclampsia in Central Asian and European populations (INTERPREGGEN)
Date du début: 1 nov. 2011, Date de fin: 31 oct. 2016,
Pre-eclampsia, one of the most dangerous cardiometabolic complications of pregnancy, claims the lives of 50,000 mothers and almost one million babies annually. Pre-eclampsia and other hypertensive disorders of pregnancy remain the second most common cause of maternal death. The incidence of pre-eclampsia in Central Asian countries is over twice as high as in western Europe. Inter-population differ ...
Voir le projet
13
Participants partenaires
TERMINÉ
Towards Early diagnosis and biomarker validation in Arthritis Management (EURO-TEAM)
Date du début: 1 nov. 2012, Date de fin: 31 oct. 2016,
An ideal intervention in a chronic inflammatory disease such as Rheumatoid Arthritis (RA) would be a preventive one. In order to develop preventive strategies and therapies two key developments need to occur: (1) Biomarkers need to be identified that can be used to predict an individual’s risk of developing RA. (2) Modifiable disease mechanisms need to be identified and characterized in the early ...
Voir le projet
17
Participants partenaires
TERMINÉ
Interdisciplinary training network for Tourette Syndrome; structuring European Training capacities for neurodevelopmental disorders (TS-EUROTRAIN)
Date du début: 1 oct. 2012, Date de fin: 30 sept. 2016,
There is a striking lack in structured and standardized training infrastructure for neurodevelopmental disorders across Europe. Such training will be fundamental to promoting standards of care across Europe and will ultimately lead to strategies for the promotion of childhood mental health in Europe. The focus of this Initial Training Network (ITN) is Gilles de la Tourette Syndrome (TS), an inheri ...
Voir le projet
12
Participants partenaires
TERMINÉ
Psychiatric Diagnostic and Prevention Consortium (PSYCHDPC)
Date du début: 1 janv. 2012, Date de fin: 31 juil. 2016,
PsychDPC contains leading European centres in genetics and psychiatry, richly endowed with expertise in both clinical and basic research. The partners bring together state-of-the-art technical facilities, high academic standards as well as established training activities, which will be utilized in concert to maximise the outcome of the project. The primary aim of PsychDPC is to translate data emer ...
Voir le projet
6
Participants partenaires
TERMINÉ
Novel Methods leading to New Medications in Depression and Schizophrenia (NEWMEDS)
Date du début: 1 sept. 2009, Date de fin: 28 févr. 2015,
Despite dramatic advances in molecular and imaging technologies and nearly 1 5,000 articles on schizophrenia and depression (S&D) there are few novel treatments. We think this is because of three major “bottle-necks”: a lack of etiologically-driven or pathophysiologically-accurate animal models; a lack of tests that provide indication of efficacy in healthy volunteers; and the reliance of clinical ...
Voir le projet
20
Participants partenaires
TERMINÉ
Genetic prostate cancer variants as biomarkers of disease progression (PROMARK)
Date du début: 1 janv. 2008, Date de fin: 31 déc. 2012,
Prostate cancer is the most common cancer in males in Europe, causing over 87,000 deaths in 2006. Early diagnosis and treatment are key factors in determining survival but screening methods based on the commonly-used PSA blood test have low specificity and result in excessive treatment of localized lesions that might never progress to symptomatic cancer. Biomarkers that help determine which of the ...
Voir le projet