6 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Diagnostic Imaging Strategies for Patients with Stable Chest Pain and Intermediate Risk of Coronary Artery Disease: Comparative Effectiveness Research of Existing Technologies (DISCHARGE)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,
Coronary artery disease (CAD) is the leading cause of death in high-income countries. Invasive coronary angiography (ICA) is the reference standard for the diagnosis of CAD and allows immediate therapy. However, only 40% of patients undergoing ICA actually have obstructive CAD and ICA has relatively rare but considerable risks. Coronary computed tomography (CT) is the most accurate diagnostic test ...
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38
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TERMINÉ
Phase I/II Gene Therapy Trial of Fanconi anemia patients with a new Orphan Drug consisting of a lentiviral vector carrying the FANCA gene: A Coordinated International Action (EUROFANCOLEN)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,
Fanconi anemia (FA) is a rare inherited syndrome characterized by the early development of bone marrow failure and increasing predisposition to cancer with age. Allogeneic hematopoietic cell transplantation (alloHCT) is the only curative therapy for hematopoietic manifestations of FA, although associated with complications arising from myeloablation, graft versus host disease and increased inciden ...
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13
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TERMINÉ
Benznidazol and Triazol REsearch group for Nanomedicine and Innovation on Chagas diseasE (BERENICE)
Date du début: 1 sept. 2012, Date de fin: 31 août 2017,
The BERENICE consortium is aiming at providing a new and cost-effective solution to a better treatment for Chagas chronic patients. Please see its objectives below :Main objective• Obtain a more effective, better tolerated and cheaper formulation of a drug with trypanocidal activity to cure Chagas diseaseSpecific Objectives• Obtain results of pharmacokinetics of new formulations• Assess trypanocid ...
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10
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TERMINÉ
Development of a universal influenza vaccine based on tandem core technology (FLUTCORE)
Date du début: 1 sept. 2013, Date de fin: 31 mars 2017,
"FLUTCORE will develop a novel universal influenza A virus (IAV) vaccine based on the tandem core vaccine platform. Recent influenza pandemics have emphasized the urgent need for better vaccines that are reactive with multiple IAV subtypes and that are no longer dependent on intimate knowledge of the prevalent virus. We propose to replace the existing seasonal IAV vaccine with a virus like particl ...
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7
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TERMINÉ
Glioma Actively Personalized Vaccine Consortium (GAPVAC)
Date du début: 1 nov. 2012, Date de fin: 31 janv. 2017,
"Glioblastoma (GBM) is a rare (2-3 incidences in 100,000) and fatal disease. Each year, approximately 13,000 new cases of GBM are diagnosed in Europe. The 5-year survival rate of this highly aggressive tumor entity under conventional therapy is less than 6%. Currently available therapeutic options neglect the individuality of each patients’ disease and only temporarily influence tumor progression ...
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13
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TERMINÉ
Best EScalation Treatment in Multiple Sclerosis (MS) (BEST MS)
Date du début: 1 nov. 2012, Date de fin: 31 oct. 2016,
"Multiple Sclerosis (MS) is a devastating disease of the central nervous system affecting 2.5 million worldwide. MS is a field of constant therapeutic innovation, a fact which brings hope to young adults since MS is one of the most frequent causes of severe handicap. A major unmet need is to rationalize treatment decisions. To date, there is no way of predicting which patients will best respond to ...
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