5 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Hepatic and Cardiac Toxicity Systems modelling (HECATOS)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2018,
HeCaToS aims at developing integrative in silico tools for predicting human liver and heart toxicity. The objective is to develop an integrated modeling framework, by combining advances in computational chemistry and systems toxicology, for modelling toxic perturbations in liver and heart across multiple scales. This framework will include vertical integrations of representations from drug(metabol ...
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14
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TERMINÉ
OncoTrack - Methods for systematic next generation oncology biomarker development (ONCOTRACK)
Date du début: 1 janv. 2011, Date de fin: 31 déc. 2016,
We propose here an exhaustive analysis of the genome, exome, methylome and transcriptome of primary tumours and metastases from patients with colon carcinoma, based on a combination of deep sequencing and chip based techniques. Dependent on their availability, we shall also perform analyses of tumor stem cells, circulating tumor cells, free tumor DNA in serum and xenografts derived from the same p ...
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22
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TERMINÉ
Pharmacoepidemiolocal Research on Outcomes of Therapeutics by a European ConsorTium (PROTECT)
Date du début: 1 sept. 2009, Date de fin: 30 avr. 2015,
Recent pharmacovigilance (PV) issues have led to questions regarding the ability of the current PV system to meet the global needs. Controversies around the assessment of spontaneous reports and conflicting results from pharmacoepidemiology studies may lead to delay in, or inappropriate, regulatory decisions. The PROTECT consortium, consisting of 20 core partners lead by the European Medicines Age ...
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36
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TERMINÉ
Predicting individual response and resistance to VEGFR/mTOR pathway therapeutic intervention using biomarkers discovered through tumour functional genomics (PREDICT)
Date du début: 1 janv. 2011, Date de fin: 31 déc. 2014,
"The strategic development of accurate biomarkers to predict response to therapy in cancer medicine will enhance clinical outcome and reduce the health economic impact of drug resistant disease. The PREDICT consortium will identify and validate predictive biomarkers for two drugs which have direct anti-tumour cell and anti-angiogenic activity and for which no established predictive biomarkers of t ...
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16
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TERMINÉ
Breakthrough in European Ship and Shipbuilding Technologies (BESST)
Date du début: 1 sept. 2009, Date de fin: 28 févr. 2013,
"Initiated by EUROYARDS, BESST aims to achieve a breakthrough in competitiveness, environmentally friendliness and safety of EU built ships. Focusing on passenger ships, ferries and mega-yachts, the results will to a large extend be applicable also to other ships. A holistic life cycle performance assessment on ship level will guide the technical developments on system level, clustered in System G ...
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