4 projets européens trouvés
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TERMINÉ
European Urban Health Indicators Part Two: Using indicators to inform policy (EURO-URHIS 2)
Date du début: 1 janv. 2009, Date de fin: 30 juin 2013,
"Urban health is important due urbanisation and requires specific information not captured by national datasets. The EURO-URHIS (www.urhis.eu) project funded by DG SANCO, identified urban health indicators and their availability. EURO-URHIS 2 aims to develop methodology and validated tools useful to policy makers at all levels to make health gains via evidence based policy decisions for urban popu ...
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19
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TERMINÉ
A pharmacogenomic approach to coumarin anticoagulant therapy (EU-PACT)
Date du début: 1 oct. 2008, Date de fin: 31 mars 2013,
"The effectiveness of treatment with oral anticoagulants in the prevention of thrombotic disorders is well established, but these drugs are potentially dangerous because of their narrow therapeutic index. In Europe three coumarins are used: warfarin, acenocoumarol, and phenprocoumon. Genetic factors that have been recently demonstrated to change the pharmacokinetics and pharmacodynamics of coumari ...
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12
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TERMINÉ
EUropean Research initiative to develop Imaging Probes for early In-vivo Diagnosis and Evaluation of response to therapeutic Substances (EURIPIDES)
Date du début: 1 févr. 2008, Date de fin: 31 juil. 2012,
"We aim develop in-vivo imaging biomarker of multidrug transporter function as a generic tool for the prediction, diagnosis, monitoring and prognosis of major CNS diseases, as well as to provide support and guidance for therapeutic interventions. Multidrug transporters actively transport substrates (including multiple CNS drugs) against concentration gradients across the blood-brain barrier (BBB). ...
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14
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TERMINÉ
INTEGRATION OF THE SYSTEM MODELS OF INSULIN SIGNALLING AND OF MITOCHONDRIAL FUNCTION AND ITS APPLICATION IN THE STUDY OF COMPLEX DISEASES (MITIN)
Date du début: 1 nov. 2008, Date de fin: 31 oct. 2011,
"A common trait to disorders such as type 2 diabetes or obesity is the development of insulin resistance. There is evidence indicating the existence of a bidirectional cross-talk between insulin signalling and mitochondrial function that may be relevant for the pathogenesis of those disorders. Based on this, MITIN main goal is to identify novel mitochondrial-dependent mechanisms responsible for th ...
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