3 projets européens trouvés
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TERMINÉ
Metagenomics in Cardiometabolic Diseases (METACARDIS)
Date du début: 1 nov. 2012, Date de fin: 31 oct. 2018,
METACARDIS applies a systems medicine multilevel approach to identify biological relationships between gut microbiota, assessed by metagenomics, and host genome expression regulation, which will improve understanding and innovative care of cardiometabolic diseases (CMD) and their comorbidities. CMD comprise metabolic (obesity, diabetes) and heart diseases characterized by a chronic evolution in ag ...
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18
Participants partenaires
TERMINÉ
Biological Foundation for the Safety Classification of Engineered Nanomaterials (ENM): Systems Biology Approaches to Understand Interactions of ENM with Living Organisms and the Environment (NANOSOLUTIONS)
Date du début: 1 avr. 2013, Date de fin: 31 mars 2017,
The main objective of this research proposal is to identify and elaborate those characteristics of ENM that determine their biological hazard potential. This potential includes the ability of ENM to induce damage at the cellular, tissue, or organism levels by interacting with cellular structures leading to impairment of key cellular functions. These adverse effects may be mediated by ENM-induced a ...
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40
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TERMINÉ
Systems biology of liver cancer: an integrative genomic-epigenomic approach (MODHEP)
Date du début: 1 janv. 2011, Date de fin: 30 juin 2016,
"Cancer is a complex disease involving multiple genetic and epigenetic events occurring, and influencing each other, over a long period of time. Understanding cancer, and ultimately developing effective targeted therapies, will therefore require that mutations and epigenetic alterations be systematically investigated during the multiple stages of disease development, from identifiable pre-neoplast ...
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