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Control of mouse metabolism by circadian clock-coordinated mRNA translation (CIRCATRANS)
Date du début: 1 mars 2011, Date de fin: 29 févr. 2016,
The mammalian circadian clock plays a fundamental role in the liver by regulating fatty acid, glucose and xenobiotic metabolism. Impairment of this rhythm has been show to lead to diverse pathologies including metabolic syndrome. At present, it is supposed that the circadian clock regulates metabolism mostly by regulating the expression of liver enzymes at the transcriptional level. We have now co ...
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