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 TERMINÉ 

Vaccination against Shigella and ETEC: novel antigens, novel approaches (STOPENTERICS)

Date du début: 1 nov. 2010, Date de fin: 30 avr. 2017,

To contribute to the development of vaccines against Shigella and ETEC for children of the developing world, STOPENTERICS will provide novel solutions by imposing a two-fold paradigm switch: (i) to break the dogma of serotype-specificity by inducing a cross-protective immunity (ii) to improve the immunogenicity of Shigella glycoconjugates by using synthetic oligosacharides mimicking the lipopolysa ...
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 20

 TERMINÉ 

Regenerating Bone defects using New biomedical Engineering approaches (REBORNE)

Date du début: 1 janv. 2010, Date de fin: 30 juin 2015,

Bone is among the most frequently transplanted tissue with about 1 million procedures annually in Europe. The worldwide market of bone replacement materials is currently estimated at 5 billion € with a 10% annual growth. Despite their considerable disadvantages, including the risk of disease transfer and immunologic rejection, limited supply of bone, costs and complications, allografts and autogra ...
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 24

 TERMINÉ 

Sub-seabed CO2 Storage: Impact on Marine Ecosystems (ECO2) (ECO2)

Date du début: 1 mai 2011, Date de fin: 30 avr. 2015,

The ECO2 project sets out to assess the risks associated with the storage of CO2 below the seabed. Carbon Capture and Storage (CCS) is regarded as a key technology for the reduction of CO2 emissions from power plants and other sources at the European and international level. The EU will hence support a selected portfolio of demonstration projects to promote, at industrial scale, the implementation ...
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 29

 TERMINÉ 

Construction kit for tailor-made vascularized boneimplants (VascuBone)

Date du début: 1 janv. 2010, Date de fin: 31 mars 2015,

The goal of VascuBone is to develop a “tool box” for bone regeneration, which on one hand fulfils basic requirements and on the other hand is freely combinable with what is needed in the respective patient’s situation. The tool box will include a variation of biocompatible biomaterials and cell types, FDA approved growth factors, material modification technologies, simulation and analytical tools ...
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 18

 TERMINÉ 

Changes in carbon uptake and emissions by oceans in a changing climate (CARBOCHANGE)

Date du début: 1 mars 2011, Date de fin: 28 févr. 2015,

CARBOCHANGE will provide the best possible process-based quantification of net ocean carbon uptake under changing climate conditions using past and present ocean carbon cycle changes for a better prediction of future ocean carbon uptake. We will improve the quantitative understanding of key biogeochemical and physical processes through a combination of observations and models. We will upscale new ...
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 30

 TERMINÉ 

Multi-disciplinary University Traditional Health Initiative (MUTHI): Building Sustainable Research Capacity on Plants for Better Public Health in Africa (MUTHI)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2014,

It is recognised that research must be a basis for better health throughout Africa (e.g. Global Ministerium Forum on Research for Health, Bamako 2008, Beijing declaration 2008). As a consequence It is a priority to build research capacities in the African continent that will set good standards for development of improved health security and systems in the future. In several African countries west ...
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 9

 TERMINÉ 

European Plate Observing System (EPOS)

Date du début: 1 nov. 2010, Date de fin: 31 oct. 2014,

To understand the complex Earth System requires an integrated observational strategy and infrastructure to record key diagnostic features of its dynamics. Accordingly, this infrastructure must include geographically distributed and multidisciplinary monitoring instruments and observations. The European Plate Observing System (EPOS) will meet this challenge. The proposed RI (EPOS) will create a sin ...
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 23

 TERMINÉ 

Svalbard Integrated Arctic Earth Observing System - Preparatory Phase (SIOS-PP)

Date du début: 1 oct. 2010, Date de fin: 30 sept. 2014,

"Environmental change and climate change in particular, are expected to be most pronounced in the polar regions. For this reason, a multi-disciplinary research infrastructure covering all important elements of the coupled Earth System in the Arctic is a very valuable tool to quantify the ongoing global change and to verify the capability of Earth System models to predict future changes. The propos ...
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 26

 TERMINÉ 

Interruption of protein-protein interaction and network to cancer biomarkers and therapeutic targets (PPI-MARKER)

Date du début: 1 août 2010, Date de fin: 31 juil. 2014,

Protein-protein interactions are keys to executing important cellular functions. We hypothesize that gain or loss of protein-protein interactions plays important roles in carcinogenesis. We propose a network-based approach to biomarker discovery that uses protein-protein interactions and regulatory transcriptional networks. We will use prostate cancer and gliomas as models. Prostate cancer is the ...
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 3

 TERMINÉ 

"Promoting sexual- and reproductive health among adolescents in southern and eastern Africa – mobilising parents, schools, and communities" (PREPARE)

Date du début: 1 févr. 2010, Date de fin: 31 juil. 2014,

"The purpose of this project is to develop research-based, culture- and gender-sensitive, sustainable, community-based interventions to promote sexual- and reproductive health among adolescents aged 12-14 years in southern and East Africa, with schools as the gateway for delivery. In two sites (Cape Town and Dar es Salaam), comprehensive, 'best practice', effectiveness studies will be implemented. ...
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 9

 TERMINÉ 

Common Language Resources and their Applications (CLARA)

Date du début: 1 déc. 2009, Date de fin: 31 mars 2014,

"CLARA will train a new generation of linguistic experts who will be able to cooperate across national boundaries on the establishment of a common language resources infrastructure and its exploitation for the construction of the next generation of language models with wide theoretical and applied significance. The scientific objectives of the CLARA research context are twofold: 1. to develop the ...
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 11

 TERMINÉ 

Treatment of reperfusion injury using a mitochondrial targeted approach: towards a better understanding of the disease (MITOCARE)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2013,

"Current interventional treatment of acute myocardial infarction (AMI) focused on re-establishing cardiac reperfusion has significantly improved clinical outcome by reducing infarct size and mortality due to cardiac ischemia.It is now recognized that events triggered at reperfusion also result in cell death and may account for as much as 50% of the infarct volume, this being termed ischemia-reperf ...
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 18

 TERMINÉ 

Comprehensive Modelling of the Earth system for better climate prediction and projection (COMBINE)

Date du début: 1 mai 2009, Date de fin: 31 oct. 2013,

"The European integrating project COMBINE brings together research groups to advance Earth system models (ESMs) for more accurate climate projections and for reduced uncertainty in the prediction of climate and climate change in the next decades. COMBINE will contribute to better assessments of changes in the physical climate system and of their impacts in the societal and economic system. The pro ...
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 24

 TERMINÉ 

Nucleosome Structure & Function across Biological Scales and Biological Function (NUCLEOSOME4D)

Date du début: 1 nov. 2009, Date de fin: 31 oct. 2013,

Chromatin packages a few meters of DNA into a nucleus measuring a few microns. This tight folding occurs by assembling DNA with histones into so-called nucleosomes, thus ensuring the mechanical stability of our genome. On the flipside, this makes nucleosomes a formidable obstacle to the machines that read, copy or repair its DNA message. One of the fundamental questions in biology is to understand ...
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 17

 TERMINÉ 

European Collaborative Project on Inflamation and Vascular Wall Remodelling in Atherosclerosis (ATHEROREMO)

Date du début: 1 mai 2008, Date de fin: 31 oct. 2013,

"The health of the EC population has never been better. However, serious public health problems remain, which cannot be ignored including high levels of premature death due to cardiovascular diseases. Thus, new preventive, diagnostic and therapeutic strategies against atherosclerotic cardiovascular diseases are needed. The atherosclerotic changes of the vascular wall are central in the developmen ...
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 19

 TERMINÉ 

Promoting Adolescent health through an intervention aimed at improving the quality of their participation in Physical Activity (PAPA)

Date du début: 1 avr. 2009, Date de fin: 30 sept. 2013,

The background of this project is related to the role of sport in two recent White Papers from the Commission on an integrated EU approach to reducing ill health and enhancing public health, the White Paper on A Strategy for Europe on Nutrition, Overweight and Obesity related health issues and the White Paper on Sport. The project centres on the development and validation of a new method in healt ...
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 8

 TERMINÉ 

Microbial and viral ecology of hot spring environments with emphasis on 454 pyrosequencing and microbial and viral interactions (MicVirEcolHotSprings)

Date du début: 15 août 2010, Date de fin: 14 août 2013,

Lithotrophic organisms use inorganic substrate for biosynthesis. These “rock eating” microorganisms living in subsurface environments comprise great proportion of the biomass found on and inside our earth and hot springs represent accessible windows to sample the deep biosphere. Microorganisms isolated from hot springs are known to use hydrogen as an energy source. In this project we will add hydr ...
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 1

 TERMINÉ 

Building a biological knowledge-base on fish lifecycles for competitive, sustainable European aquaculture (LIFECYCLE)

Date du début: 1 févr. 2009, Date de fin: 31 juil. 2013,

LIFECYCLE (14 partners, 9 countries) will deliver a knowledge-base to improve competitiveness and sustainability of European aquaculture, through a combination of question-problem driven approaches. The focus will be on early developmental events, growth and environmental adaptation throughout the lifecyle, and on the physiology and immunology of key life-stage transitions, such as metamorphosis, ...
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 14

 TERMINÉ 

Knowledge-based Sustainable Management for Europe's Seas (KnowSeas)

Date du début: 1 avr. 2009, Date de fin: 30 juin 2013,

Europe’s four regional seas (Baltic, Black, Mediterranean and NE Atlantic) have suffered severe environmental degradation due to human pressure. Existing measures to manage pressures have proven inadequate and the EC has responded by proposing a new policy (Maritime Strategy Blue Book) and environmental legislation (Marine Strategy Directive), both currently close to adoption. These instruments re ...
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 34

 TERMINÉ 

Monitoring and Assessing Regional Climate change in High latitudes and the Arctic (MONARCH-A)

Date du début: 1 mars 2010, Date de fin: 31 mai 2013,

"By adopting an Earth system approach the ultimate goal of MONARCH-A is to generate a dedicated information package tailored to a subset of multidisciplinary Essential Climate Variables and their mutual forcing and feedback mechanisms associated with changes in terrestrial carbon and water fluxes, sea level and ocean circulation and the marine carbon cycle in the high latitude and Arctic regions. ...
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 8

 TERMINÉ 

Marine Ecosystem Evolution in a Changing Environment (MEECE)

Date du début: 1 sept. 2008, Date de fin: 28 févr. 2013,

MEECE is a scientific research project which aims to use a combination of data synthesis, numerical simulation and targeted experimentation to further our knowledge of how marine ecosystems will respond to combinations of multiple climate change and anthropogenic drivers. With an emphasis on the European Marine Strategy (EMS), MEECE will improve the decision support tools to provide a structured l ...
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 22

 TERMINÉ 

Alcohol Measures for Public Health Research Alliance (AMPHORA) (AMPHORA)

Date du début: 1 janv. 2009, Date de fin: 31 déc. 2012,

"AMPHORA is a Europe wide project involving researches and research institutions from 14 European countries, and counterparts and organizations from all 27 Member States, that will provide new scientific evidence for the best public health measures to reduce the harm done by alcohol through addressing social and cultural determinants, marketing and advertising, taxes and pricing, availability and ...
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 33

 TERMINÉ 

Gene- Environment Interactions in Heart Development (CHeartED)

Date du début: 1 janv. 2009, Date de fin: 31 déc. 2012,

Cardiovascular malformation (CVM) is the commonest cause of childhood death in developed countries. In the EU there are 51,000 new cases each year and two million affected individuals. Yet, despite intensive research, the cause of 80% of CVM remains elusive. The mission of CHeartED is to identify genetic and environmental pathways that can be modified with the goal of reducing preventable CVM inci ...
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 11

 TERMINÉ 

Thermohaline Overturning - at Risk? (THOR)

Date du début: 1 déc. 2008, Date de fin: 30 nov. 2012,

"THOR will establish an operational system that will monitor and forecast the development of the North Atlantic THC on decadal time scales and access its stability and the risk of a breakdown in a changing climate. Together with pre-existing data sets, ongoing observations within the project will allow precise quantitative monitoring of the Atlantic THC and its sources. This will, for the first ti ...
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 21

 TERMINÉ 

Genomic Regulatory Systems of Human X-linked neurological diseases (NeuroXsys)

Date du début: 1 juin 2009, Date de fin: 30 nov. 2012,

NeuroXsys will generate regulatory maps and models of the human X chromosome based on evolutionary conservation, with special attention to genes and regions implicated in X-linked neurological diseases. Vertebrate chromosomes are subdivided into domains of genomic regulatory blocks (GRBs) and NeuroXsys aims to map all GRBs on the X chromosome through bioinformatic approaches, extract gene regulato ...
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 9

 TERMINÉ 

Calcification by Marine Organisms (CalMarO)

Date du début: 1 oct. 2008, Date de fin: 30 sept. 2012,

CalMarO aims at the comprehensive training of twelve young researchers in the field of calcification by marine organisms based on a Network of thirteen research institutions and four SMEs. The Network participants are acknowledged experts with complementary research or commercial approaches in this field. Calcification is a fundamental physiological process of marine organisms that is largely det ...
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 9

 TERMINÉ 

Quantifying Arctic responses to past climate change (QUARCTIC)

Date du début: 1 août 2010, Date de fin: 31 juil. 2012,

"The ability to anticipate the projected consequences of anthropogenic greenhouse warming in the coming centuries is critical if policy makers are to implement realistic and achievable mitigation measures. The levels of predictive precision currently available through global circulation models (GCM’s) is, however, insufficient for this task due to shortcomings in their ability to realistically sim ...
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 1

 TERMINÉ 

"Public Perception of Genetically modified Animals - Science, Utility and Society" (PEGASUS)

Date du début: 1 août 2009, Date de fin: 31 juil. 2012,

"PEGASUS aims to provide policy support regarding the development, implementation and commercialisation of GM animals, and derivative foods. The results will contribute to the FP7 KBBE by integrating existing social, (including existing public perception) environmental and economic knowledge regarding GM animals. The use of GM in farmed animals (aquatic and terrestrial) will be reviewed. A foresig ...
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 12

 TERMINÉ 

4D Space-Time Topology for Semantic Flow Segmentation (SemSeg)

Date du début: 1 juin 2009, Date de fin: 30 juin 2012,

The thorough analysis of flows plays an important role in many different processes, such as airplane and car design, environmental research, and medicine. Scientific visualization and its subfield flow visualization have provided a variety of techniques for the domain experts to visually analyze large and complex flow data sets. Among them, so-called topological methods play an important role. ...
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 4

 TERMINÉ 

European Project on Ocean Acidification (EPOCA)

Date du début: 1 mai 2008, Date de fin: 30 avr. 2012,

"The overall goal of the European Project on Ocean Acidification (EPOCA) is to fill the numerousgaps in our understanding of the effects and implications of ocean acidification.EPOCA aims to document the changes in ocean chemistry and biogeography across space and time.Paleo-reconstruction methods will be used on several archives, including foraminifera and deep-seacorals, to determine past variab ...
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 28

 TERMINÉ 

Nasal Pandemic Influenza Vaccine (NASPANVAC)

Date du début: 1 mai 2008, Date de fin: 30 avr. 2012,

"The project is being undertaken in response to the need to develop an effective, user friendly, heat stable vaccine to control the highly pathogenic form of avian influenza virus (H5 and H7 subtypes) which has the potential to cause another global influenza pandemic. The overall objective of this programme is to develop a nasal avian influenza vaccine using ChiSys® (chitosan), which is a chitosan ...
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 8

 TERMINÉ 

Tackling the Gradient: Applying Public Health Policies to Effectively Reduce Health Inequalities amongst Families and Children (GRADIENT)

Date du début: 1 avr. 2009, Date de fin: 31 mars 2012,

"Health inequalities are currently regarded as one of the most important public health challenges in the EU. There is however not sufficient knowledge of what actions are effective to reduce the gradient in health inequalities. 'Tackling the Gradient' aims to address this, to ensure that political momentum is maintained and that operational strategies can be developed to make progress on this issu ...
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 12

 TERMINÉ 

Pathophysiology and natural course of autoimmune adrenal failure in Europe (Euradrenal)

Date du début: 1 avr. 2008, Date de fin: 31 mars 2012,

Autoimmune Addison’s disease (AAD) is an endocrine disease resulting from the immune system’s destruction of hormone producing cells in the adrenal cortex. Diagnosis is frequently first established after a life-threatening adrenal crisis, often resulting in untimely fatalities. The disease is rare, more common in women than in men, and also affects children. AAD very frequently occurs with other a ...
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 12

 TERMINÉ 

"Towards the mechanism and function of tunneling nanotube (TNT)-dependent, intercellular exchange of cargo" (FP7 TNT FUNCTION)

Date du début: 1 avr. 2010, Date de fin: 31 mars 2012,

"Tunneling nanotubes (TNTs), recently discovered thin membrane channels connecting distant cells, represent the underlying structure of a previously unrecognized type of cell-to-cell communication. To date, a growing number of cell types have been found to use TNTs for the intercellular exchange of diverse cargoes ranging from cytoplasmic signalling molecules such as calcium ions to small vesicles ...
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 1

 TERMINÉ 

Science Created by You (SCY) (SCY)

Date du début: 1 mars 2008, Date de fin: 29 févr. 2012,

Description The SCY system for constructive and productive learning of science and technology will be based on a flexible and adaptive pedagogical approach to learning and on learning objects created by learners.SCY's basic philosophy is that the learning of science is a process of creating knowledge by learners. The overall objective of ...
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 17

 TERMINÉ 

Study of Strongly Interacting Matter (HadronPhysics2)

Date du début: 1 janv. 2009, Date de fin: 31 déc. 2011,

The Project promotes the access to five European Research Infrastructures, and it is structured intop eight Networking Activities, plus the Management of the Consortium, and fourteen Joint Research Activities. The Project represents the continuation of the successful HadronPhysics project in FP6 and originates from the initiative of more than 2.500 European scientists working in the field of hadro ...
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 46

 TERMINÉ 

The Landscape and Isobars of European Values in Relation to Science and New Technology (Value Isobars)

Date du début: 1 juin 2009, Date de fin: 30 nov. 2011,

The goal of this project is to provide the blueprints for a value-based and value-informed new and flexible governance of the science-society relation in Europe. Furthermore, the study shall identify necessary research tasks in order to move from a generic understanding of value-based and value-informed governance to more specific mechanisms of governance that improve current practice. Emerging bi ...
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 6

 TERMINÉ 

a Transdisciplinary approach to the Emerging CHallenges of NOvel technologies: Lifeworld and Imaginaries in Foresight and Ethics (TECHNOLIFE)

Date du début: 1 mars 2009, Date de fin: 30 nov. 2011,

"The TECHNOLIFE project will approach the SiS 5.1.1.2 call by developing new ethical frameworks to address ethical concerns of Europeans in relation to three technological fields: ICTs, Geographical Imaging Systems and converging technologies to enhance the human body. It will supply valuable insights on how issues of ethical concern to groups, publics and citizens can be considered in EC policy i ...
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 9

 TERMINÉ 

Coordination Action Carbon Observation System (COCOS)

Date du début: 1 mai 2008, Date de fin: 31 oct. 2011,

"COCOS will assess the status of harmonization of key carbon cycle variables with international partners. It will improve the interoperability of data sets that are used in global scale carbon cycle studies through joint activities between ecosystem, atmospheric and ocean bottom-up and top down observation communities. COCOS will also perform integrated regional-scale multiple constraint assessmen ...
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 11

 TERMINÉ 

Common Language Resources and Technology Infrastructure (CLARIN)

Date du début: 1 janv. 2008, Date de fin: 30 juin 2011,

The ultimate goal of CLARIN is the construction and operation of a shared distributed infrastructure that aims at making language resources and technology available to the humanities and social sciences research communities at large. The preparatory phase will pave the way for implementation along 4 dimensions: Funding and governance: The aim is to bring together the funding agencies and to work o ...
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 36