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Epigenetic control and impact of mammalian retrotransposons in pluripotent genomes (EPIPLURIRETRO)
Date du début: 1 juil. 2013, Date de fin: 30 juin 2018,
Almost half of the human genome is made of Transposable Elements (TEs), whose ongoing activity continually impacts our genome. However, little is known about how the host regulates TEs and their genomic and epigenomic impacts. EpiPluriRetro will advance research in a new groundbreaking concept: that TEs are active in our pluripotent genome, and that epigenetic regulation is employed therein to reg ...
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