2 projets européens trouvés
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TERMINÉ
Generation of a new class of antiretrovirals targeting HIV-cellular cofactors interactions (HIVINNOV)
Date du début: 1 oct. 2012, Date de fin: 30 sept. 2015,
Highly active antiretroviral therapy is effective at controlling HIV-1 replication, however emergence and transmission of drug-resistant viruses is increasing, including viruses resistant to the newly developped integrase catalytic inhibitors. It is essential that new antiretrovirals (ARVs) become available. Most ARVs in development belong to the classes of viral enzyme inhibitors. Since HIV requi ...
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TERMINÉ
Host and viral factors in acute hepatitis C (HEPACUTE)
Date du début: 1 nov. 2010, Date de fin: 30 avr. 2014,
Chronic hepatitis C is one of the most common chronic viral infections of humans and a major cause of chronic liver disease, cirrhosis and liver cancer. Still about 4 million new infections occur world-wide each year with 50-85% of patients progressing to chronic hepatitis C. Currently there is no marker to predict spontaneous viral clearance and to guide treatment decisions.The major objectives o ...
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