2 projets européens trouvés
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TERMINÉ
MicroRNAs in the Pathogenesis, Treatment and Prevention of Epilepsy (EPIMIRNA)
Date du début: 1 sept. 2013, Date de fin: 31 août 2018,
Epilepsy is a major burden for patients and health systems worldwide. It is a common chronic neurological disorder affecting people of all ages, and the shortfall in existing treatments means that 30% of patients continue to suffer uncontrolled seizures. MicroRNAs (miRNA) are a recently-discovered, network-level layer of gene expression regulation that controls protein levels of entire signaling p ...
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TERMINÉ
Novel tumor-selective lethal miRNAs for the treatment of head and neck cancer (MIRACLE)
Date du début: 1 oct. 2013, Date de fin: 31 oct. 2016,
...y combining two innovative technologies, i.e. therapeutic miRNA and head and neck tumor specific targeted drug delivery. Such a project requires (1) expertise in the therapeutic application of miRNA (InteRNA) and knowledge on the synthesis of biochemical active miRNA (Biospring), (2) knowledge of drug formulations to deliver the therapeutic miRNA into humans (IC) and understanding the synthesis of ...
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