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Epigenetics and DNA repair. Is a chromatin remodeling process involved in the higher UV sensitivity of nucleotide excision repair defective cells? (EPINER2007)
Date du début: 1 juin 2010, Date de fin: 31 mai 2011,
"The knowledge on regulatory roles of epigenetic mechanisms (heritable changes in the genome function without a change in the DNA sequence) has grown very fast during the last decade since they can be the target for treating several pathologies related to cancer and neurodegeneration. In the base of these diseases deficiencies in DNA repair mechanisms have also been found. In this respect, two hum ...
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