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 TERMINÉ 
We propose here an exhaustive analysis of the genome, exome, methylome and transcriptome of primary tumours and metastases from patients with colon carcinoma, based on a combination of deep sequencing and chip based techniques. Dependent on their availability, we shall also perform analyses of tumor stem cells, circulating tumor cells, free tumor DNA in serum and xenografts derived from the same p ...
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 22

 TERMINÉ 
"Dysregulation of lipid homeostasis is related to multiple major global healthcare problems today, including aging, diabetes and cardiovascular disease. It has already been shown that nutritional modulation of lipid homeostasis via direct supplementation, e.g., n-3 fatty acids, or via indirect mechanisms, e.g., dietary polyphenols, has beneficial effects on human health. There is growing evidence ...
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 11

 TERMINÉ 
Lipids are central to the regulation and control of cellular processes by acting as basic building units for biomembranes, the platforms for the vast majority of cellular functions. Recent developments in lipid mass spectrometry have set the scene for a completely new way to understand the composition of membranes, cells and tissues in space and time by allowing the precise identification and quan ...
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 27

 TERMINÉ 

Virtual multidisciplinary EnviroNments USing Cloud infrastructures (VENUS-C)

Date du début: 1 juin 2010, Date de fin: 31 mai 2012,

Several research communities in Europe exploit e-Infrastructures, sharing data and computing resources with Grid and Supercomputing technology. However the inherent complexity of these technologies has limited their wider adoption and their long term sustainability: designing, developing and operating a computing infrastructure for an e-Science community remains challenging and costly.VENUS-C will ...
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 16

 TERMINÉ 
The research program is a multidisciplinary functional genomics approach to study fundamental biological processes relevant to human health and to develop bioinformatics tools in systems biology. It will decipher the complex regulatory networks that control basic cellular processes in the context of intracellular pathogen infection as a paradigm of host/pathogen genomes conflict.This project will ...
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 9